ENSG00000078269

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355585 ENSG00000078269 No_inf pgKDN_inf SYNJ2 protein_coding protein_coding 27.54589 10.71635 37.76378 0.2939766 1.289622 1.816225 8.6701108 2.8786558 12.4330296 0.1304409 0.8454775 2.1068676 0.3043083 0.268500 0.332625 0.064125 8.290051e-01 6.502539e-07 FALSE TRUE
ENST00000367112 ENSG00000078269 No_inf pgKDN_inf SYNJ2 protein_coding protein_coding_CDS_not_defined 27.54589 10.71635 37.76378 0.2939766 1.289622 1.816225 0.6393808 0.8264559 0.6285038 0.3901600 0.2099475 -0.3895942 0.0365250 0.079600 0.016200 -0.063400 4.740534e-01 6.502539e-07 FALSE TRUE
ENST00000367113 ENSG00000078269 No_inf pgKDN_inf SYNJ2 protein_coding protein_coding 27.54589 10.71635 37.76378 0.2939766 1.289622 1.816225 3.6770012 2.4702122 5.3398350 0.4929008 3.0930083 1.1090309 0.1536250 0.229425 0.134675 -0.094750 6.204659e-01 6.502539e-07 FALSE FALSE
ENST00000367122 ENSG00000078269 No_inf pgKDN_inf SYNJ2 protein_coding protein_coding 27.54589 10.71635 37.76378 0.2939766 1.289622 1.816225 5.2588632 3.5901306 6.9624980 0.4814614 1.3700466 0.9536264 0.2227750 0.332425 0.182375 -0.150050 4.297963e-01 6.502539e-07 FALSE TRUE
MSTRG.25583.6 ENSG00000078269 No_inf pgKDN_inf SYNJ2 protein_coding   27.54589 10.71635 37.76378 0.2939766 1.289622 1.816225 8.0376866 0.0000000 11.5231691 0.0000000 2.5456704 10.1715733 0.2256167 0.000000 0.311275 0.311275 6.502539e-07 6.502539e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000078269 E001 3.1140714 0.0046431620 3.253772e-01 0.6178970498 6 157981863 157981953 91 + 0.621 0.474 -0.680
ENSG00000078269 E002 4.8848539 0.0073051164 1.898208e-02 0.1226817957 6 157981954 157982037 84 + 0.809 0.474 -1.458
ENSG00000078269 E003 4.3118978 0.0037434556 2.598029e-01 0.5523577380 6 157982038 157982088 51 + 0.731 0.577 -0.660
ENSG00000078269 E004 0.0000000       6 158017048 158017203 156 +      
ENSG00000078269 E005 7.1976652 0.0019862482 2.934431e-01 0.5870386339 6 158017204 158017290 87 + 0.909 0.789 -0.464
ENSG00000078269 E006 0.0000000       6 158017465 158017795 331 +      
ENSG00000078269 E007 0.2457744 0.0161461940 4.505540e-01   6 158026985 158027075 91 + 0.061 0.145 1.390
ENSG00000078269 E008 1.8957075 0.0069546465 3.052895e-02 0.1644082212 6 158027076 158027165 90 + 0.514 0.145 -2.517
ENSG00000078269 E009 0.7335152 0.0618720035 2.587239e-01 0.5511716420 6 158027367 158028755 1389 + 0.162 0.340 1.390
ENSG00000078269 E010 27.3381792 0.0063723475 9.326229e-05 0.0022445374 6 158028756 158029026 271 + 1.480 1.184 -1.032
ENSG00000078269 E011 1.2037649 0.0113331263 8.683285e-01 0.9548371089 6 158029027 158029406 380 + 0.313 0.340 0.168
ENSG00000078269 E012 24.9132041 0.0086955217 4.246008e-05 0.0011630483 6 158030408 158031000 593 + 1.448 1.110 -1.186
ENSG00000078269 E013 1.8232166 0.0383633752 3.254337e-01 0.6179173960 6 158033455 158033489 35 + 0.373 0.529 0.805
ENSG00000078269 E014 7.3807805 0.0050401437 3.854450e-01 0.6714650205 6 158033490 158033680 191 + 0.857 0.951 0.355
ENSG00000078269 E015 2.9805809 0.0047068383 5.995020e-02 0.2456396127 6 158043316 158043399 84 + 0.636 0.340 -1.484
ENSG00000078269 E016 2.7412310 0.0051763060 9.474728e-02 0.3202243839 6 158054967 158055028 62 + 0.605 0.340 -1.347
ENSG00000078269 E017 3.8424672 0.0067341609 4.642771e-01 0.7338442944 6 158059257 158059353 97 + 0.679 0.577 -0.446
ENSG00000078269 E018 0.3634701 0.0165515808 7.974246e-01   6 158059354 158059537 184 + 0.115 0.145 0.390
ENSG00000078269 E019 4.5828086 0.0031333236 8.555482e-01 0.9491670231 6 158061992 158062054 63 + 0.706 0.729 0.095
ENSG00000078269 E020 5.6401506 0.0025117503 5.147604e-01 0.7711753948 6 158062055 158062164 110 + 0.809 0.729 -0.320
ENSG00000078269 E021 5.2476025 0.0027112142 2.699331e-02 0.1526695705 6 158063791 158063872 82 + 0.829 0.529 -1.273
ENSG00000078269 E022 5.3834240 0.0026124316 1.249436e-01 0.3747683803 6 158064601 158064750 150 + 0.819 0.620 -0.819
ENSG00000078269 E023 8.9201774 0.0016476685 8.837702e-01 0.9609464381 6 158064826 158064991 166 + 0.955 0.970 0.055
ENSG00000078269 E024 11.1633828 0.0179089490 4.543823e-01 0.7270553538 6 158066444 158066635 192 + 1.069 0.988 -0.300
ENSG00000078269 E025 5.0536315 0.0027811175 8.367850e-01 0.9415181996 6 158068647 158068728 82 + 0.755 0.729 -0.105
ENSG00000078269 E026 6.4899150 0.0021096441 5.574020e-01 0.7993790557 6 158069533 158069673 141 + 0.857 0.789 -0.267
ENSG00000078269 E027 0.2442663 0.0162542544 4.507773e-01   6 158070128 158070506 379 + 0.061 0.145 1.390
ENSG00000078269 E028 9.0734827 0.0016423294 1.504648e-02 0.1052961040 6 158071602 158071794 193 + 1.028 0.760 -1.025
ENSG00000078269 E029 10.0058694 0.0226181092 9.721673e-01 0.9947660217 6 158074580 158074738 159 + 1.003 1.005 0.006
ENSG00000078269 E030 7.2189797 0.0530417257 7.152807e-01 0.8852823278 6 158076626 158076782 157 + 0.892 0.842 -0.195
ENSG00000078269 E031 0.9878525 0.3011038789 9.227089e-02 0.3154699473 6 158077680 158078163 484 + 0.162 0.474 2.128
ENSG00000078269 E032 5.0455300 0.0029702376 5.784481e-01 0.8116444338 6 158078164 158078281 118 + 0.766 0.696 -0.288
ENSG00000078269 E033 0.9803956 0.0935041874 2.120942e-01 0.4972652670 6 158078282 158079356 1075 + 0.205 0.412 1.390
ENSG00000078269 E034 11.1840714 0.0013846700 9.378624e-03 0.0771077260 6 158081109 158081327 219 + 0.969 1.195 0.818
ENSG00000078269 E035 6.0219319 0.0336750858 9.376388e-01 0.9820870530 6 158081432 158081510 79 + 0.809 0.816 0.028
ENSG00000078269 E036 12.3571919 0.0228731350 4.344130e-01 0.7117080357 6 158083429 158083597 169 + 1.112 1.022 -0.328
ENSG00000078269 E037 13.3952764 0.0353005136 4.652880e-01 0.7343721952 6 158084001 158084174 174 + 1.096 1.172 0.272
ENSG00000078269 E038 9.5093875 0.0014919500 8.382487e-01 0.9420538276 6 158086855 158086989 135 + 0.990 0.970 -0.075
ENSG00000078269 E039 8.8255973 0.0016993428 3.247218e-01 0.6171695850 6 158088660 158088772 113 + 0.925 1.022 0.361
ENSG00000078269 E040 9.5578753 0.0212196120 3.573454e-01 0.6469859650 6 158089839 158089947 109 + 0.955 1.053 0.363
ENSG00000078269 E041 11.8533130 0.0013754557 2.737312e-01 0.5674482347 6 158092926 158093104 179 + 1.041 1.136 0.346
ENSG00000078269 E042 0.3720293 0.0165902111 1.603916e-01   6 158093888 158094094 207 + 0.061 0.253 2.390
ENSG00000078269 E043 312.7137573 0.0003884292 3.053219e-06 0.0001223576 6 158095618 158099181 3564 + 2.436 2.497 0.202

Help

Please Click HERE to learn more details about the results from DEXseq.