ENSG00000078369

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000378609 ENSG00000078369 No_inf pgKDN_inf GNB1 protein_coding protein_coding 188.8935 142.8182 218.305 2.669436 4.459321 0.612131 81.017715 47.160187 100.354208 4.7260848 7.137730 1.0892976 0.41841667 0.332375 0.459625 0.12725 0.2327320729 0.0003246652 FALSE TRUE
ENST00000615252 ENSG00000078369 No_inf pgKDN_inf GNB1 protein_coding protein_coding 188.8935 142.8182 218.305 2.669436 4.459321 0.612131 5.042399 12.663918 2.105175 6.3654458 2.105175 -2.5830139 0.03290833 0.087075 0.009925 -0.07715 0.3400464006 0.0003246652 FALSE TRUE
ENST00000703700 ENSG00000078369 No_inf pgKDN_inf GNB1 protein_coding protein_coding 188.8935 142.8182 218.305 2.669436 4.459321 0.612131 53.612519 60.501774 49.552458 5.3281955 4.551004 -0.2879681 0.29970000 0.422500 0.227400 -0.19510 0.0018229781 0.0003246652 FALSE TRUE
ENST00000703707 ENSG00000078369 No_inf pgKDN_inf GNB1 protein_coding protein_coding 188.8935 142.8182 218.305 2.669436 4.459321 0.612131 10.444657 0.000000 12.159939 0.0000000 7.100415 10.2491063 0.04881667 0.000000 0.054450 0.05445 0.8003024166 0.0003246652 FALSE TRUE
ENST00000703709 ENSG00000078369 No_inf pgKDN_inf GNB1 protein_coding protein_coding 188.8935 142.8182 218.305 2.669436 4.459321 0.612131 13.942387 2.713529 27.713743 0.7735632 5.941844 3.3475730 0.06834167 0.019250 0.128150 0.10890 0.0003246652 0.0003246652 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000078369 E001 0.0000000       1 1785285 1785285 1 -      
ENSG00000078369 E002 10.3766327 2.493494e-03 7.858155e-01 9.174873e-01 1 1785286 1785309 24 - 1.043 1.066 0.082
ENSG00000078369 E003 10.6217778 5.418085e-03 7.719542e-01 9.121988e-01 1 1785310 1785311 2 - 1.052 1.076 0.089
ENSG00000078369 E004 11.9823268 2.761928e-03 4.708518e-01 7.384392e-01 1 1785312 1785314 3 - 1.084 1.143 0.212
ENSG00000078369 E005 12.2185955 3.242707e-03 5.874345e-01 8.169250e-01 1 1785315 1785316 2 - 1.099 1.143 0.158
ENSG00000078369 E006 20.0808031 1.274651e-02 2.369503e-01 5.259342e-01 1 1785317 1785334 18 - 1.278 1.369 0.318
ENSG00000078369 E007 51.8707109 3.973820e-03 4.818973e-03 4.823851e-02 1 1785335 1785375 41 - 1.654 1.791 0.464
ENSG00000078369 E008 45.6410742 7.923774e-04 7.800617e-04 1.238047e-02 1 1785376 1785385 10 - 1.592 1.743 0.513
ENSG00000078369 E009 77.0111449 5.424676e-04 3.096738e-05 8.874574e-04 1 1785386 1785433 48 - 1.818 1.964 0.490
ENSG00000078369 E010 83.8704686 3.378090e-04 5.052931e-06 1.899127e-04 1 1785434 1785476 43 - 1.852 2.003 0.507
ENSG00000078369 E011 162.7745435 3.698884e-04 4.565226e-07 2.277714e-05 1 1785477 1785636 160 - 2.153 2.275 0.409
ENSG00000078369 E012 144.0918326 1.267547e-04 2.914885e-09 2.301778e-07 1 1785637 1785828 192 - 2.087 2.234 0.495
ENSG00000078369 E013 45.4226104 2.034978e-03 2.356035e-04 4.780677e-03 1 1785829 1785833 5 - 1.577 1.752 0.592
ENSG00000078369 E014 72.6035787 3.638069e-04 1.573128e-05 5.029347e-04 1 1785834 1785881 48 - 1.789 1.942 0.516
ENSG00000078369 E015 123.4782088 2.733059e-04 6.636749e-03 6.074095e-02 1 1785882 1786002 121 - 2.058 2.132 0.246
ENSG00000078369 E016 762.4638869 7.309111e-05 1.157049e-02 8.852357e-02 1 1786003 1786845 843 - 2.869 2.894 0.082
ENSG00000078369 E017 202.3063417 5.875024e-04 4.943094e-01 7.558701e-01 1 1786846 1786965 120 - 2.299 2.314 0.048
ENSG00000078369 E018 188.1591159 1.611640e-04 5.508795e-02 2.338407e-01 1 1786966 1787053 88 - 2.294 2.250 -0.149
ENSG00000078369 E019 7.7693308 4.977346e-02 6.322936e-02 2.529456e-01 1 1787054 1787321 268 - 0.817 1.056 0.898
ENSG00000078369 E020 205.1804386 9.778226e-05 4.382127e-03 4.519901e-02 1 1787322 1787437 116 - 2.339 2.277 -0.207
ENSG00000078369 E021 1.3962687 9.620073e-03 4.544169e-05 1.232203e-03 1 1787987 1788239 253 - 0.000 0.611 15.398
ENSG00000078369 E022 5.1489539 2.705804e-03 2.388755e-01 5.278720e-01 1 1788240 1789052 813 - 0.722 0.855 0.527
ENSG00000078369 E023 91.1091484 2.837719e-03 5.750953e-01 8.097426e-01 1 1789053 1789060 8 - 1.953 1.973 0.067
ENSG00000078369 E024 274.9421764 2.278865e-04 3.240495e-01 6.165515e-01 1 1789061 1789269 209 - 2.448 2.428 -0.067
ENSG00000078369 E025 266.7736218 8.635965e-05 3.870157e-03 4.151124e-02 1 1790395 1790596 202 - 2.450 2.395 -0.184
ENSG00000078369 E026 143.0798179 1.258962e-04 2.103775e-03 2.656016e-02 1 1793245 1793311 67 - 2.191 2.111 -0.269
ENSG00000078369 E027 4.3794449 5.361980e-03 1.273185e-05 4.200662e-04 1 1793312 1794197 886 - 0.397 0.947 2.389
ENSG00000078369 E028 185.8757848 1.204889e-04 8.611710e-05 2.102598e-03 1 1804419 1804525 107 - 2.308 2.218 -0.300
ENSG00000078369 E029 122.2070971 1.831695e-03 2.775591e-03 3.254320e-02 1 1804526 1804581 56 - 2.131 2.031 -0.333
ENSG00000078369 E030 140.8197556 2.273679e-03 4.207214e-03 4.401306e-02 1 1806475 1806538 64 - 2.190 2.095 -0.316
ENSG00000078369 E031 203.0431340 2.829774e-03 4.884443e-03 4.875764e-02 1 1815756 1815862 107 - 2.345 2.257 -0.293
ENSG00000078369 E032 0.1265070 1.236468e-02 4.075350e-01   1 1817687 1817836 150 - 0.000 0.107 11.945
ENSG00000078369 E033 107.1437186 3.161005e-04 1.063698e-02 8.361681e-02 1 1817837 1817875 39 - 2.066 1.987 -0.263
ENSG00000078369 E034 0.6251720 1.493416e-02 9.717206e-02 3.246935e-01 1 1817876 1818386 511 - 0.084 0.326 2.389
ENSG00000078369 E035 2.6053781 5.456074e-03 3.276986e-02 1.716599e-01 1 1824988 1825396 409 - 0.397 0.692 1.389
ENSG00000078369 E036 95.7987434 1.655465e-04 6.679862e-02 2.604428e-01 1 1825397 1825466 70 - 2.009 1.951 -0.197
ENSG00000078369 E037 64.4586969 2.253130e-04 1.273286e-02 9.393405e-02 1 1825467 1825499 33 - 1.855 1.758 -0.326
ENSG00000078369 E038 0.1170040 1.172540e-02 7.060560e-01   1 1825500 1825554 55 - 0.084 0.000 -12.272
ENSG00000078369 E039 0.5060281 7.662457e-01 2.559178e-01 5.480024e-01 1 1832232 1832482 251 - 0.000 0.326 12.538
ENSG00000078369 E040 0.2458395 1.647085e-02 8.322021e-01   1 1833840 1834127 288 - 0.084 0.107 0.389
ENSG00000078369 E041 61.3074253 2.392581e-04 7.123689e-04 1.149982e-02 1 1839190 1839238 49 - 1.848 1.713 -0.455
ENSG00000078369 E042 0.2357071 1.567114e-02 3.508812e-01   1 1839629 1839682 54 - 0.155 0.000 -13.175
ENSG00000078369 E043 1.2124537 1.453594e-02 8.406562e-01 9.428146e-01 1 1847878 1848036 159 - 0.359 0.326 -0.196
ENSG00000078369 E044 0.9787620 1.218163e-02 7.027373e-01 8.790800e-01 1 1848461 1848529 69 - 0.268 0.326 0.389
ENSG00000078369 E045 3.7002284 3.850235e-03 6.863596e-02 2.645285e-01 1 1852570 1852680 111 - 0.552 0.781 0.974
ENSG00000078369 E046 5.5898460 4.423652e-03 6.916312e-04 1.124261e-02 1 1853152 1853297 146 - 0.601 0.986 1.536
ENSG00000078369 E047 0.7344331 3.988002e-01 9.188128e-01 9.743996e-01 1 1853996 1854163 168 - 0.215 0.265 0.391
ENSG00000078369 E048 0.2533610 1.604949e-02 1.622396e-01   1 1858597 1858772 176 - 0.000 0.193 12.866
ENSG00000078369 E049 0.1265070 1.236468e-02 4.075350e-01   1 1876583 1876806 224 - 0.000 0.107 11.945
ENSG00000078369 E050 3.6911998 3.844331e-03 1.445532e-01 4.047729e-01 1 1879787 1879902 116 - 0.578 0.761 0.776
ENSG00000078369 E051 0.4997349 2.807031e-02 2.082929e-01   1 1889964 1890091 128 - 0.084 0.265 1.974
ENSG00000078369 E052 1.0904139 1.389736e-02 5.506355e-01 7.948458e-01 1 1890188 1890363 176 - 0.359 0.265 -0.611
ENSG00000078369 E053 1.6155477 8.315619e-03 6.174002e-02 2.496354e-01 1 1890364 1890493 130 - 0.268 0.547 1.559
ENSG00000078369 E054 69.9564069 3.322572e-03 2.739680e-08 1.792814e-06 1 1890820 1891024 205 - 1.945 1.694 -0.845
ENSG00000078369 E055 1.4527502 1.538465e-01 5.596068e-01 8.006137e-01 1 1891025 1891117 93 - 0.433 0.326 -0.612
ENSG00000078369 E056 0.0000000       1 1891998 1892112 115 -      
ENSG00000078369 E057 0.0000000       1 1892113 1892246 134 -      
ENSG00000078369 E058 0.0000000       1 1892247 1892292 46 -      

Help

Please Click HERE to learn more details about the results from DEXseq.