ENSG00000078618

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000352171 ENSG00000078618 No_inf pgKDN_inf NRDC protein_coding protein_coding 86.99603 80.35112 87.311 0.5695265 2.104635 0.1198311 41.025418 24.85809 48.426961 0.7629885 2.791472 0.9618124 0.46735833 0.309550 0.556975 0.247425 0.0007105715 0.0007105715 FALSE TRUE
ENST00000440943 ENSG00000078618 No_inf pgKDN_inf NRDC protein_coding protein_coding 86.99603 80.35112 87.311 0.5695265 2.104635 0.1198311 6.746781 11.79063 3.362688 1.5749426 3.362688 -1.8068936 0.07856667 0.146875 0.036125 -0.110750 0.0246710848 0.0007105715 FALSE TRUE
ENST00000485608 ENSG00000078618 No_inf pgKDN_inf NRDC protein_coding protein_coding_CDS_not_defined 86.99603 80.35112 87.311 0.5695265 2.104635 0.1198311 16.045083 20.64607 18.085163 1.7993905 2.960039 -0.1909621 0.19062500 0.256925 0.209275 -0.047650 0.8141570488 0.0007105715 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000078618 E001 0.0000000       1 51789191 51789195 5 -      
ENSG00000078618 E002 0.0000000       1 51789196 51789209 14 -      
ENSG00000078618 E003 0.0000000       1 51789210 51789211 2 -      
ENSG00000078618 E004 0.0000000       1 51789212 51789216 5 -      
ENSG00000078618 E005 46.0128738 0.0038752136 7.672578e-04 1.224298e-02 1 51789217 51789327 111 - 1.582 1.751 0.575
ENSG00000078618 E006 63.8087046 0.0002616551 7.753653e-02 2.849063e-01 1 51789328 51789408 81 - 1.779 1.844 0.219
ENSG00000078618 E007 39.7442745 0.0059639428 4.311372e-01 7.087802e-01 1 51789409 51789433 25 - 1.631 1.586 -0.153
ENSG00000078618 E008 1.6331370 0.0083170080 4.623057e-03 4.682440e-02 1 51789539 51789567 29 - 0.163 0.590 2.662
ENSG00000078618 E009 77.2565723 0.0002046170 7.726894e-02 2.844050e-01 1 51789568 51789657 90 - 1.864 1.923 0.198
ENSG00000078618 E010 23.2708269 0.0005828125 4.341323e-07 2.177816e-05 1 51789658 51790532 875 - 1.206 1.519 1.089
ENSG00000078618 E011 88.7861612 0.0001662815 2.759209e-03 3.242946e-02 1 51790533 51790649 117 - 1.905 1.999 0.314
ENSG00000078618 E012 79.2173807 0.0001936721 1.201029e-01 3.664026e-01 1 51790900 51790990 91 - 1.879 1.930 0.171
ENSG00000078618 E013 77.3311351 0.0002435023 9.283424e-01 9.787530e-01 1 51791578 51791661 84 - 1.893 1.895 0.006
ENSG00000078618 E014 50.3262881 0.0002774611 9.427184e-01 9.841203e-01 1 51792046 51792098 53 - 1.709 1.711 0.006
ENSG00000078618 E015 45.2219493 0.0003178892 7.374377e-01 8.958776e-01 1 51792377 51792424 48 - 1.658 1.672 0.046
ENSG00000078618 E016 70.6831324 0.0002106441 5.293159e-02 2.286777e-01 1 51794472 51794610 139 - 1.821 1.889 0.228
ENSG00000078618 E017 13.7661312 0.0010128382 5.177171e-01 7.731567e-01 1 51794823 51794854 32 - 1.193 1.142 -0.183
ENSG00000078618 E018 5.3329653 0.0026686639 6.094285e-03 5.715298e-02 1 51794855 51795139 285 - 0.623 0.935 1.253
ENSG00000078618 E019 1.7385579 0.0078473814 6.145885e-02 2.490212e-01 1 51795140 51795708 569 - 0.282 0.559 1.525
ENSG00000078618 E020 0.0000000       1 51798249 51798411 163 -      
ENSG00000078618 E021 51.9258836 0.0002854356 8.694836e-01 9.551341e-01 1 51800556 51800683 128 - 1.721 1.726 0.019
ENSG00000078618 E022 0.2541163 0.0159916284 1.972835e-01   1 51800857 51801094 238 - 0.000 0.183 11.114
ENSG00000078618 E023 90.6807336 0.0002429173 5.287895e-01 7.802937e-01 1 51803814 51803964 151 - 1.953 1.972 0.062
ENSG00000078618 E024 52.3907048 0.0003679685 9.355481e-01 9.815051e-01 1 51805510 51805561 52 - 1.726 1.728 0.007
ENSG00000078618 E025 84.6333494 0.0001942580 3.291062e-01 6.215426e-01 1 51806794 51806913 120 - 1.917 1.948 0.102
ENSG00000078618 E026 54.6645389 0.0002776524 5.707351e-01 8.070697e-01 1 51809315 51809401 87 - 1.757 1.733 -0.082
ENSG00000078618 E027 28.5879997 0.0005434759 9.624343e-01 9.918462e-01 1 51810281 51810290 10 - 1.470 1.472 0.005
ENSG00000078618 E028 60.6424778 0.0004960143 5.940214e-02 2.445458e-01 1 51810291 51810404 114 - 1.824 1.749 -0.253
ENSG00000078618 E029 59.1244892 0.0003244339 9.185303e-03 7.600493e-02 1 51811994 51812098 105 - 1.826 1.722 -0.350
ENSG00000078618 E030 45.4939518 0.0040527503 4.598161e-01 7.314258e-01 1 51814035 51814089 55 - 1.685 1.647 -0.132
ENSG00000078618 E031 0.6257986 0.0146588282 1.291655e-01 3.813032e-01 1 51814090 51814550 461 - 0.089 0.312 2.203
ENSG00000078618 E032 42.6398300 0.0022683554 2.139423e-01 4.991821e-01 1 51814551 51814609 59 - 1.669 1.606 -0.212
ENSG00000078618 E033 0.1268540 0.0122705350 4.662778e-01   1 51814610 51814625 16 - 0.000 0.101 10.114
ENSG00000078618 E034 55.8329980 0.0013911208 2.624829e-01 5.553282e-01 1 51814693 51814813 121 - 1.777 1.728 -0.165
ENSG00000078618 E035 6.1285006 0.0064358896 6.258299e-01 8.390968e-01 1 51815929 51816311 383 - 0.826 0.879 0.203
ENSG00000078618 E036 40.2466945 0.0005615702 3.150636e-01 6.078998e-01 1 51816312 51816389 78 - 1.638 1.589 -0.167
ENSG00000078618 E037 45.5510162 0.0068378397 2.043991e-01 4.872729e-01 1 51818066 51818135 70 - 1.701 1.628 -0.249
ENSG00000078618 E038 44.8078683 0.0031236196 1.179139e-01 3.627230e-01 1 51819800 51819873 74 - 1.698 1.617 -0.272
ENSG00000078618 E039 31.7571210 0.0004390993 7.927422e-02 2.887504e-01 1 51821498 51821555 58 - 1.558 1.464 -0.323
ENSG00000078618 E040 49.9075954 0.0002734036 6.288370e-01 8.408086e-01 1 51823664 51823786 123 - 1.717 1.695 -0.073
ENSG00000078618 E041 20.5201222 0.0093655171 9.974742e-01 1.000000e+00 1 51825287 51825296 10 - 1.333 1.332 -0.004
ENSG00000078618 E042 38.9141910 0.0031284316 6.135677e-01 8.320466e-01 1 51825297 51825382 86 - 1.614 1.586 -0.097
ENSG00000078618 E043 19.5002439 0.0128257783 5.871966e-01 8.168800e-01 1 51827796 51827798 3 - 1.333 1.287 -0.160
ENSG00000078618 E044 44.1250267 0.0003455330 7.194857e-01 8.868439e-01 1 51827799 51827869 71 - 1.647 1.662 0.051
ENSG00000078618 E045 73.8741790 0.0002073445 1.556585e-01 4.216194e-01 1 51834017 51834170 154 - 1.898 1.847 -0.171
ENSG00000078618 E046 47.9807983 0.0139341024 2.996397e-02 1.628781e-01 1 51836131 51836212 82 - 1.753 1.609 -0.490
ENSG00000078618 E047 0.0000000       1 51836344 51836368 25 -      
ENSG00000078618 E048 8.3109336 0.0016719407 9.172602e-01 9.740212e-01 1 51836369 51836438 70 - 0.964 0.973 0.033
ENSG00000078618 E049 21.1593911 0.0027995725 7.725156e-06 2.735709e-04 1 51836439 51837455 1017 - 1.174 1.475 1.053
ENSG00000078618 E050 1.8690000 0.0072554796 3.668241e-02 1.843728e-01 1 51837456 51837486 31 - 0.282 0.590 1.662
ENSG00000078618 E051 7.2593892 0.0019231466 1.484061e-01 4.102791e-01 1 51837487 51837620 134 - 0.841 0.985 0.546
ENSG00000078618 E052 4.1411539 0.0137830491 1.193669e-05 3.981406e-04 1 51839992 51840225 234 - 0.331 0.922 2.688
ENSG00000078618 E053 95.5326240 0.0001985503 2.159418e-03 2.702856e-02 1 51840226 51840514 289 - 2.028 1.932 -0.321
ENSG00000078618 E054 0.0000000       1 51862114 51862418 305 -      
ENSG00000078618 E055 0.1271363 0.0122900424 4.662756e-01   1 51871557 51871620 64 - 0.000 0.101 10.114
ENSG00000078618 E056 0.6257075 0.0148828597 1.290999e-01 3.812548e-01 1 51877983 51878274 292 - 0.089 0.312 2.202
ENSG00000078618 E057 72.4199831 0.0002133416 2.122936e-04 4.391962e-03 1 51878275 51878805 531 - 1.925 1.792 -0.447

Help

Please Click HERE to learn more details about the results from DEXseq.