ENSG00000078808

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360001 ENSG00000078808 No_inf pgKDN_inf SDF4 protein_coding protein_coding 190.2608 159.5865 193.3221 2.647877 4.362465 0.2766516 175.7391 140.7138 182.0835 3.939907 5.386064 0.3718137 0.9203333 0.8813 0.941425 0.060125 0.001578314 0.001578314 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000078808 E001 3.7532571 3.837545e-03 1.386185e-01 3.959041e-01 1 1216931 1216931 1 - 0.763 0.574 -0.803
ENSG00000078808 E002 3.8718953 3.664041e-03 1.027353e-01 3.350421e-01 1 1216932 1216933 2 - 0.781 0.574 -0.873
ENSG00000078808 E003 610.6127647 5.153232e-05 4.924103e-01 7.545883e-01 1 1216934 1217688 755 - 2.784 2.789 0.017
ENSG00000078808 E004 12.8332454 1.171324e-03 1.763069e-02 1.167047e-01 1 1217689 1217804 116 - 1.035 1.224 0.680
ENSG00000078808 E005 141.5276957 1.042484e-03 4.109097e-01 6.926382e-01 1 1218458 1218522 65 - 2.143 2.163 0.067
ENSG00000078808 E006 207.3811719 1.083806e-04 7.739749e-01 9.131262e-01 1 1218523 1218633 111 - 2.323 2.315 -0.027
ENSG00000078808 E007 2.5884495 5.466750e-03 4.514905e-01 7.245503e-01 1 1218634 1218768 135 - 0.499 0.602 0.475
ENSG00000078808 E008 257.6232164 1.192837e-04 8.219363e-01 9.354072e-01 1 1218769 1218927 159 - 2.412 2.414 0.006
ENSG00000078808 E009 4.0078197 3.589008e-03 1.760815e-04 3.771557e-03 1 1218928 1218943 16 - 0.387 0.875 2.175
ENSG00000078808 E010 4.1164812 3.436092e-03 1.788346e-03 2.342739e-02 1 1218944 1219005 62 - 0.465 0.860 1.704
ENSG00000078808 E011 54.5593857 3.926196e-04 1.843497e-39 1.603664e-36 1 1219006 1221351 2346 - 1.349 1.943 2.023
ENSG00000078808 E012 238.2763940 1.789342e-03 3.717753e-01 6.597784e-01 1 1223244 1223357 114 - 2.391 2.367 -0.078
ENSG00000078808 E013 222.6461918 1.003935e-03 8.850257e-04 1.366532e-02 1 1223832 1223968 137 - 2.387 2.309 -0.259
ENSG00000078808 E014 0.1186381 1.178954e-02 5.635025e-01   1 1227272 1227319 48 - 0.093 0.000 -8.790
ENSG00000078808 E015 353.5892404 6.526547e-04 6.829762e-03 6.204743e-02 1 1228468 1228946 479 - 2.574 2.525 -0.165
ENSG00000078808 E016 64.6231277 4.258079e-04 3.293209e-01 6.217284e-01 1 1231892 1232031 140 - 1.836 1.797 -0.131

Help

Please Click HERE to learn more details about the results from DEXseq.