ENSG00000079616

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000160827 ENSG00000079616 No_inf pgKDN_inf KIF22 protein_coding protein_coding 28.74117 30.5568 29.01882 2.295327 2.069353 -0.07447942 14.4494261 14.021666 13.421032 1.441578 1.3716057 -0.0631162 0.51000833 0.456375 0.47905 0.022675 0.98673468 0.01823937 FALSE TRUE
ENST00000565736 ENSG00000079616 No_inf pgKDN_inf KIF22 protein_coding retained_intron 28.74117 30.5568 29.01882 2.295327 2.069353 -0.07447942 1.2216643 3.664993 0.000000 2.204165 0.0000000 -8.5215976 0.03548333 0.106450 0.00000 -0.106450 0.47716454 0.01823937 FALSE TRUE
ENST00000568312 ENSG00000079616 No_inf pgKDN_inf KIF22 protein_coding nonsense_mediated_decay 28.74117 30.5568 29.01882 2.295327 2.069353 -0.07447942 1.4637982 0.000000 3.884606 0.000000 1.6355644 8.6053335 0.04795833 0.000000 0.12450 0.124500 0.01823937 0.01823937 TRUE TRUE
ENST00000689743 ENSG00000079616 No_inf pgKDN_inf KIF22 protein_coding retained_intron 28.74117 30.5568 29.01882 2.295327 2.069353 -0.07447942 0.5747514 1.279533 0.000000 1.279533 0.0000000 -7.0107043 0.02241667 0.050300 0.00000 -0.050300 0.86422293 0.01823937 TRUE TRUE
ENST00000691169 ENSG00000079616 No_inf pgKDN_inf KIF22 protein_coding retained_intron 28.74117 30.5568 29.01882 2.295327 2.069353 -0.07447942 4.1782684 2.930188 5.267076 1.077633 0.8799472 0.8438304 0.14935000 0.100950 0.18530 0.084350 0.73874825 0.01823937 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000079616 E001 0.0000000       16 29790727 29790728 2 +      
ENSG00000079616 E002 0.0000000       16 29790729 29790730 2 +      
ENSG00000079616 E003 0.0000000       16 29790731 29790731 1 +      
ENSG00000079616 E004 0.0000000       16 29790732 29790733 2 +      
ENSG00000079616 E005 0.7370151 0.1983212418 8.146227e-01 9.323260e-01 16 29790734 29790739 6 + 0.267 0.213 -0.421
ENSG00000079616 E006 0.7370151 0.1983212418 8.146227e-01 9.323260e-01 16 29790740 29790740 1 + 0.267 0.213 -0.421
ENSG00000079616 E007 0.8641515 0.2221071628 9.400480e-01 9.830357e-01 16 29790741 29790742 2 + 0.267 0.266 -0.006
ENSG00000079616 E008 0.8641515 0.2221071628 9.400480e-01 9.830357e-01 16 29790743 29790747 5 + 0.267 0.266 -0.006
ENSG00000079616 E009 0.9811555 0.0742173285 6.976377e-01 8.765786e-01 16 29790748 29790749 2 + 0.329 0.266 -0.420
ENSG00000079616 E010 0.9811555 0.0742173285 6.976377e-01 8.765786e-01 16 29790750 29790750 1 + 0.329 0.266 -0.420
ENSG00000079616 E011 0.9811555 0.0742173285 6.976377e-01 8.765786e-01 16 29790751 29790751 1 + 0.329 0.266 -0.420
ENSG00000079616 E012 1.0987861 0.0136672052 4.393869e-01 7.153434e-01 16 29790752 29790753 2 + 0.383 0.266 -0.742
ENSG00000079616 E013 1.2164167 0.0128328916 2.743909e-01 5.679472e-01 16 29790754 29790755 2 + 0.431 0.266 -1.005
ENSG00000079616 E014 1.2164167 0.0128328916 2.743909e-01 5.679472e-01 16 29790756 29790756 1 + 0.431 0.266 -1.005
ENSG00000079616 E015 6.7388720 0.0035731861 3.350380e-01 6.268857e-01 16 29790757 29790829 73 + 0.937 0.840 -0.368
ENSG00000079616 E016 0.0000000       16 29790968 29790970 3 +      
ENSG00000079616 E017 0.0000000       16 29790971 29791006 36 +      
ENSG00000079616 E018 0.1271363 0.0123784219 7.246297e-01   16 29791007 29791221 215 + 0.000 0.083 11.099
ENSG00000079616 E019 0.1271363 0.0123784219 7.246297e-01   16 29791222 29791461 240 + 0.000 0.083 11.099
ENSG00000079616 E020 0.0000000       16 29792466 29792514 49 +      
ENSG00000079616 E021 7.1028136 0.0020039880 2.559349e-01 5.480024e-01 16 29796893 29796945 53 + 0.964 0.853 -0.420
ENSG00000079616 E022 16.4452502 0.0102824378 3.404629e-01 6.320730e-01 16 29796946 29797088 143 + 1.275 1.205 -0.247
ENSG00000079616 E023 0.1170040 0.0118393987 3.964319e-01   16 29797089 29797093 5 + 0.108 0.000 -12.416
ENSG00000079616 E024 19.9840819 0.0301954784 3.112191e-01 6.044180e-01 16 29798374 29798501 128 + 1.368 1.274 -0.331
ENSG00000079616 E025 6.6037008 0.0407958849 2.845196e-01 5.782163e-01 16 29798593 29798597 5 + 0.951 0.813 -0.527
ENSG00000079616 E026 18.7696555 0.0012673388 1.972708e-01 4.785286e-01 16 29798598 29798747 150 + 1.336 1.254 -0.288
ENSG00000079616 E027 0.7427386 0.0600788065 6.517839e-01 8.533477e-01 16 29798748 29798974 227 + 0.195 0.266 0.580
ENSG00000079616 E028 22.7615914 0.0006255109 6.224000e-01 8.373273e-01 16 29798975 29799184 210 + 1.384 1.358 -0.091
ENSG00000079616 E029 29.9737908 0.0005062552 2.784507e-01 5.716875e-01 16 29799264 29799494 231 + 1.515 1.461 -0.183
ENSG00000079616 E030 0.5080420 0.0157009137 8.747781e-02 3.065601e-01 16 29799495 29799627 133 + 0.000 0.266 12.935
ENSG00000079616 E031 28.3852256 0.0005765557 3.440663e-01 6.353798e-01 16 29799628 29799781 154 + 1.428 1.483 0.191
ENSG00000079616 E032 14.9011344 0.0020207322 9.263198e-01 9.778656e-01 16 29799913 29799960 48 + 1.189 1.199 0.037
ENSG00000079616 E033 17.4773613 0.0009205911 1.032186e-02 8.196614e-02 16 29799961 29800048 88 + 1.353 1.181 -0.602
ENSG00000079616 E034 0.3720293 0.0166773931 7.860893e-01   16 29800049 29800173 125 + 0.108 0.153 0.580
ENSG00000079616 E035 15.4551355 0.0128481633 3.087718e-09 2.424061e-07 16 29800174 29802316 2143 + 0.785 1.366 2.124
ENSG00000079616 E036 1.8776539 0.0079663789 6.718287e-02 2.614249e-01 16 29802317 29802472 156 + 0.267 0.549 1.580
ENSG00000079616 E037 0.9996252 0.3962796647 4.520172e-01 7.252014e-01 16 29802473 29802507 35 + 0.195 0.356 1.164
ENSG00000079616 E038 0.4909842 0.4809957114 8.348676e-01   16 29802508 29802510 3 + 0.195 0.153 -0.422
ENSG00000079616 E039 1.6048123 0.0118731552 7.670248e-01 9.097501e-01 16 29802511 29802665 155 + 0.383 0.430 0.258
ENSG00000079616 E040 0.2533610 0.0161181035 3.626602e-01   16 29802666 29802689 24 + 0.000 0.153 12.030
ENSG00000079616 E041 0.4972804 0.0247759338 4.877952e-01   16 29802690 29802768 79 + 0.108 0.213 1.165
ENSG00000079616 E042 18.6128915 0.0103478315 1.005842e-01 3.311381e-01 16 29802769 29802847 79 + 1.353 1.233 -0.420
ENSG00000079616 E043 22.5081702 0.0077939574 7.500478e-01 9.014575e-01 16 29802848 29802937 90 + 1.374 1.358 -0.055
ENSG00000079616 E044 1.2425372 0.0101624693 4.171019e-01 6.968149e-01 16 29802938 29803398 461 + 0.267 0.395 0.802
ENSG00000079616 E045 0.8685242 0.2240372521 5.966289e-01 8.227231e-01 16 29803399 29803448 50 + 0.195 0.313 0.901
ENSG00000079616 E046 33.2093769 0.0004591160 5.185019e-01 7.735140e-01 16 29803449 29803608 160 + 1.544 1.515 -0.098
ENSG00000079616 E047 12.7162154 0.0011396149 4.413738e-01 7.168613e-01 16 29803998 29804002 5 + 1.091 1.156 0.235
ENSG00000079616 E048 12.1166948 0.0012419213 2.391951e-01 5.281348e-01 16 29804003 29804065 63 + 1.049 1.150 0.364
ENSG00000079616 E049 2.1229604 0.0066443796 1.038830e-01 3.368670e-01 16 29804066 29804107 42 + 0.329 0.574 1.280
ENSG00000079616 E050 17.2964790 0.0074996345 1.934974e-03 2.493689e-02 16 29804108 29804575 468 + 1.091 1.341 0.887
ENSG00000079616 E051 0.0000000       16 29804576 29804693 118 +      
ENSG00000079616 E052 0.0000000       16 29804694 29804726 33 +      
ENSG00000079616 E053 0.0000000       16 29804727 29804813 87 +      
ENSG00000079616 E054 4.7053669 0.0031359737 2.956892e-01 5.887150e-01 16 29804814 29805026 213 + 0.670 0.799 0.523
ENSG00000079616 E055 0.6260196 0.0151175523 2.979837e-01 5.909491e-01 16 29805027 29805114 88 + 0.108 0.266 1.580
ENSG00000079616 E056 10.7189369 0.0051006455 8.241973e-01 9.361749e-01 16 29805115 29805174 60 + 1.049 1.072 0.082
ENSG00000079616 E057 0.7625052 0.0142337683 2.388700e-02 1.414649e-01 16 29805175 29805262 88 + 0.000 0.356 13.449
ENSG00000079616 E058 13.7534587 0.0012861715 4.102459e-01 6.921528e-01 16 29805263 29805385 123 + 1.197 1.137 -0.214

Help

Please Click HERE to learn more details about the results from DEXseq.