ENSG00000080189

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000243896 ENSG00000080189 No_inf pgKDN_inf SLC35C2 protein_coding protein_coding 48.52508 43.57685 48.16571 3.124135 2.479477 0.144413 3.959101 0.000000 6.1890878 0.0000000 1.7683301 9.2759121 0.07834167 0.000000 0.130700 0.130700 3.820375e-05 3.820375e-05 FALSE TRUE
ENST00000317734 ENSG00000080189 No_inf pgKDN_inf SLC35C2 protein_coding protein_coding 48.52508 43.57685 48.16571 3.124135 2.479477 0.144413 10.925011 8.582095 11.2232027 0.9120067 2.0706629 0.3866874 0.22628333 0.198000 0.236250 0.038250 8.948011e-01 3.820375e-05 FALSE TRUE
ENST00000372227 ENSG00000080189 No_inf pgKDN_inf SLC35C2 protein_coding protein_coding 48.52508 43.57685 48.16571 3.124135 2.479477 0.144413 2.035285 3.792534 0.7067279 1.2860025 0.4089746 -2.4074637 0.04352500 0.086200 0.015375 -0.070825 5.200973e-01 3.820375e-05 FALSE TRUE
ENST00000420518 ENSG00000080189 No_inf pgKDN_inf SLC35C2 protein_coding protein_coding 48.52508 43.57685 48.16571 3.124135 2.479477 0.144413 1.040712 0.000000 3.1221348 0.0000000 3.1221348 8.2910025 0.02193333 0.000000 0.065800 0.065800 8.512894e-01 3.820375e-05 FALSE FALSE
ENST00000480329 ENSG00000080189 No_inf pgKDN_inf SLC35C2 protein_coding protein_coding_CDS_not_defined 48.52508 43.57685 48.16571 3.124135 2.479477 0.144413 4.470315 6.842637 3.2617797 1.5506721 1.9445640 -1.0665835 0.09299167 0.157450 0.065900 -0.091550 4.753380e-01 3.820375e-05 FALSE TRUE
ENST00000484318 ENSG00000080189 No_inf pgKDN_inf SLC35C2 protein_coding protein_coding_CDS_not_defined 48.52508 43.57685 48.16571 3.124135 2.479477 0.144413 2.776173 0.000000 3.8630158 0.0000000 2.2309759 8.5973136 0.04937500 0.000000 0.074475 0.074475 4.663841e-01 3.820375e-05 FALSE FALSE
ENST00000487729 ENSG00000080189 No_inf pgKDN_inf SLC35C2 protein_coding protein_coding_CDS_not_defined 48.52508 43.57685 48.16571 3.124135 2.479477 0.144413 12.084523 12.002820 9.7758968 2.8456171 3.5177037 -0.2957989 0.24661667 0.267975 0.203425 -0.064550 8.370945e-01 3.820375e-05 FALSE TRUE
MSTRG.18356.3 ENSG00000080189 No_inf pgKDN_inf SLC35C2 protein_coding   48.52508 43.57685 48.16571 3.124135 2.479477 0.144413 4.727378 4.632840 5.0864327 1.8052266 5.0864327 0.1344803 0.10533333 0.115000 0.107175 -0.007825 3.947543e-01 3.820375e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000080189 E001 0.0000000       20 46345980 46345983 4 -      
ENSG00000080189 E002 15.0630882 0.0140023099 0.0319277030 0.168882209 20 46345984 46349527 3544 - 1.095 1.285 0.673
ENSG00000080189 E003 0.4995474 0.0320990666 0.3420683586   20 46349528 46349529 2 - 0.097 0.236 1.533
ENSG00000080189 E004 75.8725911 0.0035767512 0.2322456308 0.520872249 20 46349530 46350354 825 - 1.859 1.908 0.164
ENSG00000080189 E005 46.5373368 0.0033634245 0.7928157818 0.920933809 20 46350355 46350524 170 - 1.682 1.671 -0.036
ENSG00000080189 E006 8.2106181 0.0017676940 0.0008979324 0.013801393 20 46350525 46350760 236 - 0.758 1.090 1.255
ENSG00000080189 E007 17.0357087 0.0008165420 0.9822758449 0.998625199 20 46350761 46350770 10 - 1.254 1.257 0.011
ENSG00000080189 E008 41.4615321 0.0003487259 0.6828023008 0.868584822 20 46350771 46350890 120 - 1.617 1.637 0.068
ENSG00000080189 E009 34.8394397 0.0004450184 0.6123602986 0.831370899 20 46352051 46352122 72 - 1.540 1.566 0.091
ENSG00000080189 E010 22.6359305 0.0006163289 0.1303489846 0.382980626 20 46352123 46352149 27 - 1.321 1.415 0.327
ENSG00000080189 E011 15.7853908 0.0008774108 0.0373044505 0.185949929 20 46352150 46352163 14 - 1.137 1.290 0.543
ENSG00000080189 E012 18.3590881 0.0044102649 0.0876174737 0.306715183 20 46352164 46352185 22 - 1.216 1.341 0.438
ENSG00000080189 E013 24.3514416 0.0005937404 0.1503020067 0.412875035 20 46352186 46352226 41 - 1.356 1.442 0.300
ENSG00000080189 E014 5.9980371 0.0060556804 0.0002973840 0.005763244 20 46352227 46353197 971 - 0.573 0.996 1.699
ENSG00000080189 E015 42.0934379 0.0003621233 0.3567593047 0.646610153 20 46354882 46354965 84 - 1.654 1.614 -0.135
ENSG00000080189 E016 28.9514306 0.0016996147 0.1334760417 0.388162150 20 46355073 46355103 31 - 1.517 1.435 -0.283
ENSG00000080189 E017 37.6679592 0.0003919528 0.2459007301 0.536592085 20 46355104 46355178 75 - 1.614 1.560 -0.182
ENSG00000080189 E018 23.2659355 0.0080883000 0.6366650052 0.844885635 20 46355179 46355241 63 - 1.401 1.369 -0.112
ENSG00000080189 E019 3.3154828 0.0217652411 0.9265358344 0.977995339 20 46355242 46355279 38 - 0.627 0.640 0.055
ENSG00000080189 E020 24.6829608 0.0083111150 0.2731967196 0.566988305 20 46355802 46355874 73 - 1.446 1.373 -0.252
ENSG00000080189 E021 22.9064104 0.0009184640 0.0304005718 0.164036268 20 46356574 46356637 64 - 1.442 1.311 -0.453
ENSG00000080189 E022 20.3810320 0.0006870779 0.1154592724 0.358198224 20 46357623 46357702 80 - 1.379 1.280 -0.346
ENSG00000080189 E023 18.1170871 0.0007943430 0.5697223254 0.806599394 20 46357703 46357773 71 - 1.300 1.263 -0.129
ENSG00000080189 E024 17.1731038 0.0010430396 0.0304380708 0.164148276 20 46358387 46358426 40 - 1.331 1.181 -0.526
ENSG00000080189 E025 25.5031705 0.0006111269 0.0808354031 0.292198638 20 46358427 46358558 132 - 1.472 1.373 -0.342
ENSG00000080189 E026 17.7188891 0.0008636590 0.4136311293 0.694328706 20 46358559 46358690 132 - 1.300 1.245 -0.191
ENSG00000080189 E027 13.6203874 0.0010369795 0.7884554617 0.918904677 20 46358691 46358763 73 - 1.152 1.175 0.079
ENSG00000080189 E028 8.3340935 0.0020857718 0.8747041434 0.957136344 20 46358764 46358958 195 - 0.976 0.963 -0.051
ENSG00000080189 E029 1.8597152 0.0075660345 0.2251181906 0.512754951 20 46358959 46359082 124 - 0.351 0.532 0.949
ENSG00000080189 E030 1.7042182 0.0236960081 0.5592315301 0.800501329 20 46363086 46363174 89 - 0.476 0.388 -0.466
ENSG00000080189 E031 2.1849172 0.0062826326 0.3093154441 0.602739329 20 46364040 46364370 331 - 0.573 0.429 -0.703
ENSG00000080189 E032 6.9483960 0.0020282830 0.2858837311 0.579438300 20 46364371 46364458 88 - 0.953 0.846 -0.407

Help

Please Click HERE to learn more details about the results from DEXseq.