ENSG00000080845

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340491 ENSG00000080845 No_inf pgKDN_inf DLGAP4 protein_coding protein_coding 51.24696 57.75027 51.93156 3.593597 1.508145 -0.1531883 23.130592 21.961418 26.113983 1.2671142 2.1067276 0.2497469 0.45679167 0.380900 0.505450 0.124550 0.40371217 0.02058391 FALSE  
ENST00000475894 ENSG00000080845 No_inf pgKDN_inf DLGAP4 protein_coding protein_coding 51.24696 57.75027 51.93156 3.593597 1.508145 -0.1531883 14.169135 10.603707 18.158356 3.6057085 1.9909113 0.7754993 0.28469167 0.194975 0.348375 0.153400 0.69381141 0.02058391 FALSE  
ENST00000478910 ENSG00000080845 No_inf pgKDN_inf DLGAP4 protein_coding retained_intron 51.24696 57.75027 51.93156 3.593597 1.508145 -0.1531883 5.544160 8.607604 3.433039 0.5305091 0.4710594 -1.3236043 0.10700833 0.150800 0.065825 -0.084975 0.14233456 0.02058391 FALSE  
ENST00000479951 ENSG00000080845 No_inf pgKDN_inf DLGAP4 protein_coding protein_coding_CDS_not_defined 51.24696 57.75027 51.93156 3.593597 1.508145 -0.1531883 2.594105 4.409652 1.179084 1.0467201 0.8000534 -1.8940823 0.04964167 0.077000 0.021600 -0.055400 0.31327591 0.02058391 FALSE  
ENST00000491207 ENSG00000080845 No_inf pgKDN_inf DLGAP4 protein_coding protein_coding_CDS_not_defined 51.24696 57.75027 51.93156 3.593597 1.508145 -0.1531883 1.301662 3.904985 0.000000 3.9049845 0.0000000 -8.6128628 0.01926667 0.057800 0.000000 -0.057800 0.85612850 0.02058391 FALSE  
ENST00000497862 ENSG00000080845 No_inf pgKDN_inf DLGAP4 protein_coding protein_coding_CDS_not_defined 51.24696 57.75027 51.93156 3.593597 1.508145 -0.1531883 1.574708 4.724123 0.000000 1.7927100 0.0000000 -8.8869534 0.02577500 0.077325 0.000000 -0.077325 0.02058391 0.02058391 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000080845 E001 0.0000000       20 36306336 36306338 3 +      
ENSG00000080845 E002 0.0000000       20 36306339 36306512 174 +      
ENSG00000080845 E003 0.0000000       20 36367045 36367148 104 +      
ENSG00000080845 E004 0.0000000       20 36367149 36367275 127 +      
ENSG00000080845 E005 0.0000000       20 36431646 36432716 1071 +      
ENSG00000080845 E006 0.0000000       20 36436109 36436350 242 +      
ENSG00000080845 E007 0.0000000       20 36439754 36439868 115 +      
ENSG00000080845 E008 0.0000000       20 36442727 36442777 51 +      
ENSG00000080845 E009 0.0000000       20 36446697 36446937 241 +      
ENSG00000080845 E010 0.2447669 1.635761e-02 9.330117e-01   20 36461338 36461467 130 + 0.100 0.090 -0.160
ENSG00000080845 E011 0.6164868 1.794185e-02 7.460674e-01 8.995842e-01 20 36461468 36461477 10 + 0.181 0.229 0.425
ENSG00000080845 E012 0.6164868 1.794185e-02 7.460674e-01 8.995842e-01 20 36461478 36461479 2 + 0.181 0.229 0.425
ENSG00000080845 E013 3.2920163 4.997820e-03 3.968978e-01 6.813383e-01 20 36461480 36461491 12 + 0.689 0.577 -0.482
ENSG00000080845 E014 5.4827262 4.400625e-02 3.807692e-01 6.671997e-01 20 36461492 36461510 19 + 0.873 0.751 -0.481
ENSG00000080845 E015 1.2176686 3.983416e-02 4.424098e-01 7.177411e-01 20 36461747 36461771 25 + 0.407 0.285 -0.745
ENSG00000080845 E016 100.7336744 5.481844e-03 9.521344e-02 3.212337e-01 20 36461772 36462599 828 + 2.041 1.973 -0.227
ENSG00000080845 E017 2.9393327 4.634751e-03 7.931614e-01 9.211138e-01 20 36465265 36465367 103 + 0.613 0.577 -0.160
ENSG00000080845 E018 0.6345490 1.509056e-02 2.761184e-02 1.550119e-01 20 36473119 36473172 54 + 0.000 0.334 10.894
ENSG00000080845 E019 2.1307304 6.632077e-03 1.119452e-02 8.663581e-02 20 36492383 36493057 675 + 0.250 0.628 2.062
ENSG00000080845 E020 0.7327626 1.422418e-02 8.962544e-01 9.658638e-01 20 36493058 36493185 128 + 0.250 0.229 -0.160
ENSG00000080845 E021 70.6136763 2.505794e-04 4.158329e-03 4.366731e-02 20 36496705 36496994 290 + 1.905 1.804 -0.340
ENSG00000080845 E022 33.7173816 4.191014e-04 4.610125e-02 2.105890e-01 20 36496995 36497066 72 + 1.591 1.489 -0.349
ENSG00000080845 E023 4.8740217 4.573898e-02 3.594852e-03 3.947969e-02 20 36497447 36497602 156 + 0.487 0.913 1.794
ENSG00000080845 E024 45.3471320 6.195261e-04 2.947337e-16 5.656998e-14 20 36497817 36499241 1425 + 1.412 1.800 1.321
ENSG00000080845 E025 4.3411983 4.196987e-03 6.021062e-02 2.462901e-01 20 36499242 36499321 80 + 0.585 0.817 0.965
ENSG00000080845 E026 25.2860171 5.486446e-04 9.214061e-02 3.152843e-01 20 36499588 36499602 15 + 1.469 1.370 -0.342
ENSG00000080845 E027 45.2969531 3.576556e-04 2.063857e-01 4.899826e-01 20 36499603 36499676 74 + 1.694 1.637 -0.192
ENSG00000080845 E028 2.7560615 2.289523e-02 6.853443e-03 6.219646e-02 20 36500197 36500198 2 + 0.309 0.713 2.010
ENSG00000080845 E029 45.1754116 3.245802e-04 8.301830e-01 9.384647e-01 20 36500199 36500275 77 + 1.658 1.666 0.028
ENSG00000080845 E030 88.5856206 2.669851e-03 4.684532e-01 7.366051e-01 20 36500276 36500506 231 + 1.965 1.938 -0.092
ENSG00000080845 E031 48.2847556 3.292756e-04 3.956638e-02 1.928928e-01 20 36500507 36500611 105 + 1.737 1.649 -0.299
ENSG00000080845 E032 27.8111338 5.564678e-04 4.525674e-01 7.257171e-01 20 36524250 36524325 76 + 1.481 1.438 -0.148
ENSG00000080845 E033 4.2191789 1.275969e-02 5.945121e-03 5.610572e-02 20 36524326 36524341 16 + 0.873 0.521 -1.482
ENSG00000080845 E034 0.0000000       20 36525851 36526006 156 +      
ENSG00000080845 E035 0.0000000       20 36526007 36526077 71 +      
ENSG00000080845 E036 1.7614693 1.193729e-01 2.976818e-02 1.622390e-01 20 36526813 36526816 4 + 0.181 0.577 2.425
ENSG00000080845 E037 366.5541748 7.003454e-05 3.241632e-02 1.705533e-01 20 36526817 36528637 1821 + 2.549 2.575 0.086

Help

Please Click HERE to learn more details about the results from DEXseq.