ENSG00000081014

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261842 ENSG00000081014 No_inf pgKDN_inf AP4E1 protein_coding protein_coding 10.46173 5.674471 13.39882 0.205839 0.2240129 1.238084 3.9624808 0.3980360 6.469577 0.3980360 0.1391124 3.9891312 0.323375 0.076875 0.483 0.406125 0.02305955 0.02305955 FALSE TRUE
ENST00000560508 ENSG00000081014 No_inf pgKDN_inf AP4E1 protein_coding protein_coding 10.46173 5.674471 13.39882 0.205839 0.2240129 1.238084 0.3141242 0.9423725 0.000000 0.5446986 0.0000000 -6.5734541 0.054000 0.162000 0.000 -0.162000 0.32185070 0.02305955 FALSE TRUE
ENST00000561393 ENSG00000081014 No_inf pgKDN_inf AP4E1 protein_coding nonsense_mediated_decay 10.46173 5.674471 13.39882 0.205839 0.2240129 1.238084 0.3085057 0.5763108 0.000000 0.5763108 0.0000000 -5.8735937 0.041700 0.098750 0.000 -0.098750 0.78983626 0.02305955 FALSE TRUE
ENST00000561397 ENSG00000081014 No_inf pgKDN_inf AP4E1 protein_coding protein_coding_CDS_not_defined 10.46173 5.674471 13.39882 0.205839 0.2240129 1.238084 5.8185297 3.7577520 6.929242 0.1880828 0.1912772 0.8810742 0.575875 0.662375 0.517 -0.145375 0.54124971 0.02305955   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000081014 E001 0.0000000       15 50908672 50908672 1 +      
ENSG00000081014 E002 0.0000000       15 50908673 50908682 10 +      
ENSG00000081014 E003 0.8426259 0.1572241994 0.9795940633 0.99759190 15 50908683 50908794 112 + 0.253 0.245 -0.063
ENSG00000081014 E004 2.0476543 0.0089379335 0.9921798215 1.00000000 15 50908795 50908928 134 + 0.462 0.461 -0.005
ENSG00000081014 E005 0.8443197 0.0220017683 0.9634416650 0.99228699 15 50912078 50912088 11 + 0.253 0.245 -0.064
ENSG00000081014 E006 1.4345529 0.1561369304 0.3889607182 0.67486593 15 50912089 50912149 61 + 0.412 0.245 -1.065
ENSG00000081014 E007 0.0000000       15 50915425 50915447 23 +      
ENSG00000081014 E008 2.0391067 0.1844140681 0.7182417869 0.88658715 15 50915448 50915555 108 + 0.485 0.400 -0.442
ENSG00000081014 E009 0.8337442 0.0131588326 0.3636413716 0.65251468 15 50915556 50915571 16 + 0.290 0.139 -1.327
ENSG00000081014 E010 0.0000000       15 50915572 50915972 401 +      
ENSG00000081014 E011 0.0000000       15 50918030 50918115 86 +      
ENSG00000081014 E012 1.6974155 0.1183332335 0.6552648927 0.85538428 15 50923931 50924004 74 + 0.385 0.461 0.409
ENSG00000081014 E013 3.0094367 0.0050405627 0.8833293735 0.96074628 15 50925098 50925219 122 + 0.585 0.562 -0.104
ENSG00000081014 E014 3.4702050 0.0892063164 0.4293467285 0.70758453 15 50929009 50929168 160 + 0.666 0.515 -0.679
ENSG00000081014 E015 4.3592532 0.0151961239 0.6198155657 0.83549314 15 50930805 50930971 167 + 0.681 0.744 0.258
ENSG00000081014 E016 0.0000000       15 50934536 50934623 88 +      
ENSG00000081014 E017 1.2077260 0.1402527281 0.9418781365 0.98360843 15 50934624 50934697 74 + 0.324 0.330 0.036
ENSG00000081014 E018 2.5072295 0.1233146374 0.4077430086 0.69020185 15 50941442 50941564 123 + 0.567 0.400 -0.828
ENSG00000081014 E019 2.0263095 0.0876901367 0.3455979068 0.63650722 15 50941666 50941697 32 + 0.507 0.330 -0.963
ENSG00000081014 E020 2.8686768 0.0049463956 0.1526878799 0.41684934 15 50941698 50941775 78 + 0.620 0.400 -1.064
ENSG00000081014 E021 4.4504906 0.0054898705 0.5002305426 0.76035208 15 50948020 50948159 140 + 0.735 0.644 -0.379
ENSG00000081014 E022 0.0000000       15 50949824 50949825 2 +      
ENSG00000081014 E023 4.8088619 0.0029452946 0.5414349203 0.78910855 15 50949826 50949938 113 + 0.759 0.680 -0.327
ENSG00000081014 E024 4.8830748 0.0119837728 0.0199509933 0.12684627 15 50950051 50950169 119 + 0.636 0.913 1.114
ENSG00000081014 E025 7.3491614 0.0028884958 0.7995635765 0.92478527 15 50958492 50958794 303 + 0.901 0.871 -0.114
ENSG00000081014 E026 3.3556102 0.0045198630 0.3470131608 0.63760715 15 50968263 50968377 115 + 0.651 0.515 -0.616
ENSG00000081014 E027 4.0627562 0.0035308121 0.1173228584 0.36183046 15 50984022 50984145 124 + 0.735 0.515 -0.964
ENSG00000081014 E028 9.0132171 0.0015175858 0.2977539020 0.59081864 15 50993370 50993625 256 + 1.001 0.893 -0.405
ENSG00000081014 E029 12.3303017 0.0205980354 0.0165956876 0.11222064 15 50997326 50997748 423 + 1.160 0.893 -0.982
ENSG00000081014 E030 5.0391232 0.0035677278 0.4254737354 0.70453917 15 50997749 50997883 135 + 0.783 0.680 -0.420
ENSG00000081014 E031 7.0019227 0.0019759659 0.7764334588 0.91415239 15 50999072 50999262 191 + 0.865 0.893 0.106
ENSG00000081014 E032 5.9013117 0.0079825589 0.6662079943 0.86125991 15 51001026 51001183 158 + 0.826 0.772 -0.211
ENSG00000081014 E033 156.7307830 0.0001337923 0.0009620661 0.01457121 15 51002502 51005900 3399 + 2.148 2.198 0.165

Help

Please Click HERE to learn more details about the results from DEXseq.