ENSG00000081237

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000348564 ENSG00000081237 No_inf pgKDN_inf PTPRC protein_coding protein_coding 122.0774 71.50557 159.4583 0.8367474 3.783246 1.15694 5.089926 9.577501 3.125951 1.4436945 1.943614 -1.6122519 0.0578750 0.134450 0.020125 -0.114325 0.09181404 0.01668088 FALSE TRUE
ENST00000697632 ENSG00000081237 No_inf pgKDN_inf PTPRC protein_coding protein_coding 122.0774 71.50557 159.4583 0.8367474 3.783246 1.15694 26.305394 6.778627 41.865570 2.6500015 4.777003 2.6249171 0.1941833 0.093850 0.264475 0.170625 0.28942590 0.01668088 FALSE TRUE
ENST00000697633 ENSG00000081237 No_inf pgKDN_inf PTPRC protein_coding nonsense_mediated_decay 122.0774 71.50557 159.4583 0.8367474 3.783246 1.15694 32.479389 22.311246 36.244815 0.7234489 4.062940 0.6997551 0.2761500 0.312250 0.228850 -0.083400 0.45264879 0.01668088 FALSE TRUE
ENST00000697635 ENSG00000081237 No_inf pgKDN_inf PTPRC protein_coding retained_intron 122.0774 71.50557 159.4583 0.8367474 3.783246 1.15694 4.969249 9.695822 5.211925 1.8042913 5.211925 -0.8942687 0.0552000 0.134925 0.030675 -0.104250 0.01668088 0.01668088 FALSE TRUE
MSTRG.2481.5 ENSG00000081237 No_inf pgKDN_inf PTPRC protein_coding   122.0774 71.50557 159.4583 0.8367474 3.783246 1.15694 28.968627 8.549034 45.498440 2.6100198 1.193987 2.4106142 0.2163917 0.120825 0.285325 0.164500 0.07801144 0.01668088 FALSE TRUE
MSTRG.2481.9 ENSG00000081237 No_inf pgKDN_inf PTPRC protein_coding   122.0774 71.50557 159.4583 0.8367474 3.783246 1.15694 9.402594 1.080744 11.098405 0.6336943 1.592357 3.3482677 0.0678000 0.015275 0.069800 0.054525 0.15438871 0.01668088 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000081237 E001 0.0000000       1 198638457 198638698 242 +      
ENSG00000081237 E002 0.0000000       1 198638723 198638786 64 +      
ENSG00000081237 E003 0.0000000       1 198638968 198639018 51 +      
ENSG00000081237 E004 0.0000000       1 198639019 198639024 6 +      
ENSG00000081237 E005 0.2458395 1.661739e-02 5.276887e-01   1 198639025 198639039 15 + 0.065 0.137 1.193
ENSG00000081237 E006 0.2458395 1.661739e-02 5.276887e-01   1 198639040 198639045 6 + 0.065 0.137 1.193
ENSG00000081237 E007 0.3723465 1.671017e-02 2.052034e-01   1 198639046 198639051 6 + 0.065 0.241 2.193
ENSG00000081237 E008 0.7429912 1.217737e-01 1.037957e-01 0.3367093284 1 198639052 198639056 5 + 0.122 0.394 2.192
ENSG00000081237 E009 2.0695176 8.461347e-03 3.752521e-01 0.6627864303 1 198639057 198639072 16 + 0.418 0.555 0.678
ENSG00000081237 E010 3.3882704 3.430509e-02 8.891101e-01 0.9630018335 1 198639073 198639094 22 + 0.610 0.637 0.114
ENSG00000081237 E011 3.3882704 3.430509e-02 8.891101e-01 0.9630018335 1 198639095 198639095 1 + 0.610 0.637 0.114
ENSG00000081237 E012 3.3882704 3.430509e-02 8.891101e-01 0.9630018335 1 198639096 198639096 1 + 0.610 0.637 0.114
ENSG00000081237 E013 4.4953944 4.376644e-02 4.404095e-01 0.7161649979 1 198639097 198639103 7 + 0.674 0.791 0.476
ENSG00000081237 E014 8.7125969 1.844171e-03 6.503877e-01 0.8528156174 1 198639104 198639137 34 + 0.943 0.995 0.193
ENSG00000081237 E015 0.0000000       1 198639162 198639225 64 +      
ENSG00000081237 E016 7.6082124 1.869966e-03 9.109794e-01 0.9717869788 1 198639226 198639228 3 + 0.910 0.905 -0.019
ENSG00000081237 E017 22.8372340 8.106201e-04 9.056609e-01 0.9698668072 1 198639229 198639287 59 + 1.343 1.359 0.053
ENSG00000081237 E018 24.5400362 2.083515e-03 7.228458e-01 0.8886033111 1 198639288 198639334 47 + 1.368 1.399 0.107
ENSG00000081237 E019 12.9503081 4.983694e-03 4.315533e-01 0.7092913100 1 198639335 198639341 7 + 1.091 1.167 0.273
ENSG00000081237 E020 16.1898799 1.640948e-03 7.558835e-01 0.9038333338 1 198692347 198692373 27 + 1.197 1.228 0.111
ENSG00000081237 E021 1.4435606 8.708149e-03 6.596837e-01 0.8579830751 1 198692374 198693206 833 + 0.390 0.324 -0.392
ENSG00000081237 E022 0.7164880 3.322019e-01 6.300702e-01 0.8413519271 1 198694018 198694140 123 + 0.257 0.137 -1.128
ENSG00000081237 E023 4.4636054 3.197615e-03 8.879102e-01 0.9625064731 1 198694141 198695171 1031 + 0.717 0.705 -0.048
ENSG00000081237 E024 0.7414239 8.226711e-01 4.555908e-01 0.7280543109 1 198696712 198696732 21 + 0.122 0.394 2.196
ENSG00000081237 E025 1.9504682 1.633281e-02 2.905050e-01 0.5840420450 1 198696733 198696880 148 + 0.390 0.555 0.830
ENSG00000081237 E026 0.9622349 1.169920e-02 7.193982e-01 0.8868439214 1 198696881 198696909 29 + 0.295 0.241 -0.392
ENSG00000081237 E027 31.8030308 3.267106e-03 2.735864e-06 0.0001109444 1 198699564 198699704 141 + 1.564 1.256 -1.065
ENSG00000081237 E028 2.6120574 2.382475e-02 3.039644e-04 0.0058675784 1 198699705 198700159 455 + 0.295 0.816 2.515
ENSG00000081237 E029 8.8585392 1.481527e-03 2.158497e-02 0.1330929472 1 198702387 198702530 144 + 1.030 0.791 -0.907
ENSG00000081237 E030 30.4665472 6.619475e-03 9.864908e-03 0.0795535231 1 198703298 198703372 75 + 1.517 1.344 -0.596
ENSG00000081237 E031 10.0753478 1.376153e-03 1.387167e-01 0.3960658245 1 198703373 198704471 1099 + 0.966 1.109 0.521
ENSG00000081237 E032 22.0833213 9.310586e-04 1.738048e-02 0.1155143032 1 198704472 198704498 27 + 1.380 1.219 -0.565
ENSG00000081237 E033 69.8302202 2.363855e-04 8.641957e-06 0.0003013430 1 198706734 198706952 219 + 1.869 1.694 -0.591
ENSG00000081237 E034 50.2198731 3.312698e-04 3.963197e-03 0.0421433440 1 198708133 198708261 129 + 1.717 1.588 -0.438
ENSG00000081237 E035 58.4329780 2.864341e-04 1.539561e-01 0.4190074430 1 198709687 198709824 138 + 1.761 1.707 -0.181
ENSG00000081237 E036 4.6470380 2.949137e-02 5.709639e-02 0.2388456387 1 198709825 198712728 2904 + 0.627 0.884 1.041
ENSG00000081237 E037 0.3641952 1.666450e-02 9.298566e-01   1 198712729 198712952 224 + 0.122 0.137 0.193
ENSG00000081237 E038 65.9251093 7.678688e-04 2.361947e-02 0.1405144622 1 198712953 198713072 120 + 1.822 1.735 -0.295
ENSG00000081237 E039 75.6450628 2.334867e-04 1.698358e-03 0.0224948966 1 198716682 198716840 159 + 1.888 1.774 -0.383
ENSG00000081237 E040 48.0351126 2.923668e-04 4.954041e-02 0.2195851704 1 198718094 198718168 75 + 1.687 1.601 -0.293
ENSG00000081237 E041 74.7660244 1.950674e-04 2.927370e-01 0.5863001380 1 198718169 198718302 134 + 1.860 1.828 -0.108
ENSG00000081237 E042 58.8078893 2.479292e-04 1.081881e-02 0.0846390867 1 198722416 198722476 61 + 1.778 1.674 -0.349
ENSG00000081237 E043 77.0607868 2.005220e-04 4.491329e-02 0.2071449957 1 198728340 198728448 109 + 1.883 1.816 -0.228
ENSG00000081237 E044 40.8890628 3.223282e-04 6.003285e-01 0.8249622043 1 198729137 198729171 35 + 1.599 1.580 -0.064
ENSG00000081237 E045 1.5799474 2.114183e-01 6.311532e-01 0.8418393024 1 198729634 198729765 132 + 0.361 0.455 0.514
ENSG00000081237 E046 80.8981142 2.587230e-04 3.526682e-02 0.1798166872 1 198731617 198731726 110 + 1.905 1.835 -0.236
ENSG00000081237 E047 84.3131486 1.889022e-04 3.928933e-01 0.6778914430 1 198732300 198732390 91 + 1.908 1.886 -0.076
ENSG00000081237 E048 78.0399472 1.863816e-03 4.132044e-01 0.6940443369 1 198732480 198732556 77 + 1.876 1.851 -0.084
ENSG00000081237 E049 55.6331701 2.483103e-04 7.780158e-02 0.2854329812 1 198734196 198734232 37 + 1.745 1.674 -0.238
ENSG00000081237 E050 93.7123884 7.634244e-04 2.190482e-01 0.5057438649 1 198734328 198734425 98 + 1.958 1.922 -0.120
ENSG00000081237 E051 117.6704455 3.451207e-04 8.453957e-01 0.9450824725 1 198735127 198735252 126 + 2.040 2.054 0.046
ENSG00000081237 E052 115.5002548 4.164468e-04 6.353369e-01 0.8443709361 1 198741869 198742026 158 + 2.039 2.032 -0.023
ENSG00000081237 E053 114.9255465 1.503346e-04 2.690742e-01 0.5626366997 1 198742232 198742367 136 + 2.042 2.017 -0.087
ENSG00000081237 E054 5.5044312 2.625852e-03 1.261474e-02 0.0933923549 1 198742368 198743045 678 + 0.674 0.961 1.129
ENSG00000081237 E055 126.5736247 1.269703e-04 2.737395e-01 0.5674482347 1 198744054 198744203 150 + 2.063 2.102 0.130
ENSG00000081237 E056 87.9946265 1.856488e-03 4.439406e-01 0.7186062359 1 198748109 198748199 91 + 1.907 1.944 0.124
ENSG00000081237 E057 136.4524185 2.002321e-04 3.334331e-01 0.6255201201 1 198749416 198749549 134 + 2.097 2.131 0.116
ENSG00000081237 E058 140.1165949 1.334206e-04 3.552925e-02 0.1805419978 1 198750492 198750626 135 + 2.098 2.162 0.215
ENSG00000081237 E059 0.2459655 1.656723e-02 5.279468e-01   1 198750885 198752088 1204 + 0.065 0.137 1.193
ENSG00000081237 E060 0.2356421 1.567560e-02 6.863111e-01   1 198752089 198752248 160 + 0.122 0.000 -9.288
ENSG00000081237 E061 149.2374710 1.211325e-04 3.725187e-01 0.6604240913 1 198752249 198752354 106 + 2.137 2.168 0.104
ENSG00000081237 E062 70.9223114 2.274833e-04 7.144398e-01 0.8849188755 1 198752355 198752371 17 + 1.820 1.842 0.073
ENSG00000081237 E063 0.3642603 2.260542e-01 8.960224e-01   1 198752372 198752593 222 + 0.122 0.137 0.192
ENSG00000081237 E064 196.2321227 9.960998e-05 2.620487e-02 0.1498127244 1 198752594 198752772 179 + 2.246 2.304 0.194
ENSG00000081237 E065 1.1883714 1.018344e-02 1.213354e-01 0.3687440671 1 198752773 198753304 532 + 0.390 0.137 -1.977
ENSG00000081237 E066 227.0190734 8.544426e-05 1.671893e-01 0.4377139256 1 198754269 198754404 136 + 2.316 2.353 0.123
ENSG00000081237 E067 1.2358036 1.217532e-01 9.378532e-02 0.3184777681 1 198754405 198754457 53 + 0.217 0.508 1.777
ENSG00000081237 E068 1017.3975916 1.161580e-03 5.674994e-04 0.0096408238 1 198755906 198757904 1999 + 2.959 3.014 0.182

Help

Please Click HERE to learn more details about the results from DEXseq.