ENSG00000081870

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000194214 ENSG00000081870 No_inf pgKDN_inf HSPB11 protein_coding protein_coding 71.73011 64.98746 78.66296 3.953981 2.884857 0.2754846 50.457578 35.484140 61.3949029 3.8941726 3.1266924 0.7907730 0.69509167 0.546300 0.779800 0.233500 0.005122467 0.005122467 FALSE TRUE
ENST00000371378 ENSG00000081870 No_inf pgKDN_inf HSPB11 protein_coding protein_coding 71.73011 64.98746 78.66296 3.953981 2.884857 0.2754846 3.504837 5.624287 2.8972684 0.4358849 0.4132436 -0.9545688 0.05119167 0.088625 0.037125 -0.051500 0.253878550 0.005122467 FALSE TRUE
ENST00000489675 ENSG00000081870 No_inf pgKDN_inf HSPB11 protein_coding protein_coding_CDS_not_defined 71.73011 64.98746 78.66296 3.953981 2.884857 0.2754846 2.554164 4.190124 0.8972813 0.7252666 0.2991818 -2.2108102 0.03702500 0.063250 0.011825 -0.051425 0.048184884 0.005122467   FALSE
MSTRG.1050.2 ENSG00000081870 No_inf pgKDN_inf HSPB11 protein_coding   71.73011 64.98746 78.66296 3.953981 2.884857 0.2754846 9.209465 12.927190 7.1348068 3.2575718 0.9615937 -0.8565574 0.13215000 0.198750 0.089775 -0.108975 0.374809065 0.005122467 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000081870 E001 9.2883391 0.0018893472 7.063031e-03 6.344728e-02 1 53916574 53917116 543 - 0.866 1.115 0.926
ENSG00000081870 E002 0.3716209 0.0165354540 5.810869e-01   1 53921486 53921560 75 - 0.095 0.174 1.011
ENSG00000081870 E003 0.3716209 0.0165354540 5.810869e-01   1 53921561 53921561 1 - 0.095 0.174 1.011
ENSG00000081870 E004 36.9685429 0.0004771390 9.277754e-01 9.785977e-01 1 53921562 53921767 206 - 1.580 1.578 -0.007
ENSG00000081870 E005 6.8675962 0.0436466822 6.814120e-01 8.682781e-01 1 53923533 53923903 371 - 0.865 0.923 0.219
ENSG00000081870 E006 34.2665119 0.0005283878 7.284810e-01 8.917361e-01 1 53923904 53923947 44 - 1.555 1.540 -0.050
ENSG00000081870 E007 50.5476395 0.0002822556 7.362791e-01 8.953403e-01 1 53928372 53928440 69 - 1.718 1.707 -0.037
ENSG00000081870 E008 8.2785697 0.0028404984 1.876214e-08 1.269658e-06 1 53928441 53929000 560 - 0.566 1.162 2.334
ENSG00000081870 E009 5.3244279 0.0028463141 4.580860e-02 2.096784e-01 1 53929497 53930038 542 - 0.668 0.897 0.912
ENSG00000081870 E010 63.4170259 0.0004624229 1.444037e-01 4.045559e-01 1 53930039 53930145 107 - 1.833 1.785 -0.161
ENSG00000081870 E011 0.7335491 0.0144284399 9.972291e-01 1.000000e+00 1 53939683 53939984 302 - 0.238 0.240 0.012
ENSG00000081870 E012 52.2118909 0.0003001277 2.844428e-01 5.782052e-01 1 53939985 53940097 113 - 1.745 1.707 -0.130
ENSG00000081870 E013 0.0000000       1 53940098 53940100 3 -      
ENSG00000081870 E014 17.1422329 0.0008311337 2.134259e-02 1.323093e-01 1 53945555 53945699 145 - 1.332 1.176 -0.548
ENSG00000081870 E015 1.2440488 0.0115655419 2.043221e-01 4.871803e-01 1 53946237 53946281 45 - 0.238 0.435 1.234

Help

Please Click HERE to learn more details about the results from DEXseq.