ENSG00000082213

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000325366 ENSG00000082213 No_inf pgKDN_inf C5orf22 protein_coding protein_coding 12.39053 11.49846 15.31007 0.5797418 2.483538 0.4127277 2.8278962 3.347880 0.9526264 1.3063446 0.5791390 -1.80250275 0.24710000 0.278125 0.073625 -0.204500 5.776395e-01 1.426533e-05 FALSE TRUE
ENST00000504866 ENSG00000082213 No_inf pgKDN_inf C5orf22 protein_coding protein_coding_CDS_not_defined 12.39053 11.49846 15.31007 0.5797418 2.483538 0.4127277 1.0331765 2.103776 0.5984267 0.5855546 0.3637291 -1.79666729 0.08766667 0.182050 0.039950 -0.142100 3.100606e-01 1.426533e-05 FALSE TRUE
ENST00000510659 ENSG00000082213 No_inf pgKDN_inf C5orf22 protein_coding nonsense_mediated_decay 12.39053 11.49846 15.31007 0.5797418 2.483538 0.4127277 2.8399929 2.961309 2.8954933 1.1555984 0.9664602 -0.03231547 0.25589167 0.265625 0.225775 -0.039850 9.953225e-01 1.426533e-05 FALSE TRUE
ENST00000515409 ENSG00000082213 No_inf pgKDN_inf C5orf22 protein_coding retained_intron 12.39053 11.49846 15.31007 0.5797418 2.483538 0.4127277 1.1075978 0.000000 2.9327787 0.0000000 2.1983815 8.20103526 0.06044167 0.000000 0.146975 0.146975 4.820532e-01 1.426533e-05 FALSE FALSE
MSTRG.22768.13 ENSG00000082213 No_inf pgKDN_inf C5orf22 protein_coding   12.39053 11.49846 15.31007 0.5797418 2.483538 0.4127277 2.3802940 1.719531 3.3048060 0.9942467 1.2392759 0.93854351 0.18110833 0.140225 0.205500 0.065275 8.345429e-01 1.426533e-05 FALSE FALSE
MSTRG.22768.3 ENSG00000082213 No_inf pgKDN_inf C5orf22 protein_coding   12.39053 11.49846 15.31007 0.5797418 2.483538 0.4127277 1.6614671 0.000000 4.3715909 0.0000000 1.1214068 8.77531099 0.11639167 0.000000 0.287925 0.287925 1.426533e-05 1.426533e-05 FALSE TRUE
MSTRG.22768.4 ENSG00000082213 No_inf pgKDN_inf C5orf22 protein_coding   12.39053 11.49846 15.31007 0.5797418 2.483538 0.4127277 0.4553215 1.365964 0.0000000 1.3659644 0.0000000 -7.10429933 0.04465833 0.133975 0.000000 -0.133975 8.432403e-01 1.426533e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000082213 E001 0.0000000       5 31532287 31532288 2 +      
ENSG00000082213 E002 0.1187032 0.0119042984 0.541208868   5 31532289 31532292 4 + 0.095 0.000 -10.898
ENSG00000082213 E003 0.3543453 0.0159317539 0.104061426   5 31532293 31532294 2 + 0.240 0.000 -14.197
ENSG00000082213 E004 0.3543453 0.0159317539 0.104061426   5 31532295 31532298 4 + 0.240 0.000 -14.197
ENSG00000082213 E005 0.3543453 0.0159317539 0.104061426   5 31532299 31532300 2 + 0.240 0.000 -14.197
ENSG00000082213 E006 1.3347986 0.0311456938 0.390755428 0.67612657 5 31532301 31532315 15 + 0.435 0.296 -0.818
ENSG00000082213 E007 6.0813763 0.0023514887 0.163595023 0.43250737 5 31532316 31532473 158 + 0.923 0.769 -0.595
ENSG00000082213 E008 5.8175717 0.0083066451 0.052504382 0.22772588 5 31534272 31534325 54 + 0.935 0.711 -0.877
ENSG00000082213 E009 6.0384414 0.0071769058 0.201537511 0.48394364 5 31534326 31534417 92 + 0.772 0.907 0.526
ENSG00000082213 E010 0.1170040 0.0119208789 0.541040284   5 31534418 31534597 180 + 0.095 0.000 -12.761
ENSG00000082213 E011 0.1272623 0.0125377309 0.534861274   5 31534959 31535051 93 + 0.000 0.095 11.724
ENSG00000082213 E012 7.9634138 0.0017337793 0.880221252 0.95959288 5 31535744 31535893 150 + 0.947 0.957 0.034
ENSG00000082213 E013 0.0000000       5 31538173 31538259 87 +      
ENSG00000082213 E014 8.1825484 0.0117125276 0.596149999 0.82248917 5 31538260 31538480 221 + 0.993 0.932 -0.226
ENSG00000082213 E015 2.1929331 0.0105404098 0.651531808 0.85325781 5 31538481 31538483 3 + 0.539 0.470 -0.333
ENSG00000082213 E016 9.3294530 0.0021844423 0.622037787 0.83711794 5 31538484 31538689 206 + 0.993 1.032 0.141
ENSG00000082213 E017 4.6061580 0.0055351880 0.111906069 0.35137346 5 31540949 31541011 63 + 0.839 0.645 -0.788
ENSG00000082213 E018 8.5273128 0.0147748742 0.285975471 0.57958068 5 31541281 31541402 122 + 1.034 0.920 -0.426
ENSG00000082213 E019 4.9992826 0.0032126484 0.448630570 0.72258380 5 31545646 31545670 25 + 0.823 0.732 -0.364
ENSG00000082213 E020 6.0884090 0.0025508011 0.266672986 0.56007881 5 31545671 31545712 42 + 0.910 0.787 -0.476
ENSG00000082213 E021 0.1268540 0.0123731282 0.535068590   5 31545713 31545714 2 + 0.000 0.095 11.724
ENSG00000082213 E022 1.2433251 0.0150524883 0.203774021 0.48640620 5 31548490 31548687 198 + 0.240 0.432 1.212
ENSG00000082213 E023 0.2357071 0.0158985927 0.244107205   5 31549328 31549363 36 + 0.174 0.000 -13.674
ENSG00000082213 E024 9.4142086 0.0186232662 0.643975969 0.84917728 5 31551293 31551432 140 + 1.044 0.990 -0.198
ENSG00000082213 E025 138.5384777 0.0001664938 0.002596812 0.03095574 5 31552773 31555053 2281 + 2.122 2.164 0.140

Help

Please Click HERE to learn more details about the results from DEXseq.