ENSG00000082269

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000194672 ENSG00000082269 No_inf pgKDN_inf FAM135A protein_coding nonsense_mediated_decay 7.973523 7.949014 7.249634 2.201032 0.4468513 -0.1326929 0.5358591 0.6364772 0.5983983 0.44787296 0.5983983 -0.08758326 0.08199167 0.105950 0.094350 -0.011600 8.503023e-01 5.165177e-06 FALSE TRUE
ENST00000457062 ENSG00000082269 No_inf pgKDN_inf FAM135A protein_coding protein_coding 7.973523 7.949014 7.249634 2.201032 0.4468513 -0.1326929 0.9879277 0.8347490 0.0000000 0.48812137 0.0000000 -6.40045079 0.12313333 0.120450 0.000000 -0.120450 5.062893e-01 5.165177e-06 FALSE TRUE
ENST00000505675 ENSG00000082269 No_inf pgKDN_inf FAM135A protein_coding retained_intron 7.973523 7.949014 7.249634 2.201032 0.4468513 -0.1326929 2.6867944 2.9963709 2.0493731 0.46809110 0.3866174 -0.54581777 0.34755000 0.411875 0.277175 -0.134700 7.552425e-01 5.165177e-06   FALSE
ENST00000505769 ENSG00000082269 No_inf pgKDN_inf FAM135A protein_coding protein_coding 7.973523 7.949014 7.249634 2.201032 0.4468513 -0.1326929 0.5448522 0.8424186 0.2098808 0.07020654 0.2098808 -1.95484025 0.07496667 0.123100 0.030400 -0.092700 3.692338e-01 5.165177e-06 FALSE TRUE
MSTRG.24880.4 ENSG00000082269 No_inf pgKDN_inf FAM135A protein_coding   7.973523 7.949014 7.249634 2.201032 0.4468513 -0.1326929 0.8018760 1.8263764 0.0000000 1.82637645 0.0000000 -7.52071802 0.05920000 0.126225 0.000000 -0.126225 8.357862e-01 5.165177e-06   FALSE
MSTRG.24880.8 ENSG00000082269 No_inf pgKDN_inf FAM135A protein_coding   7.973523 7.949014 7.249634 2.201032 0.4468513 -0.1326929 1.1015473 0.0000000 3.1492023 0.00000000 0.6711062 8.30341651 0.14768333 0.000000 0.424000 0.424000 5.165177e-06 5.165177e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000082269 E001 0.0000000       6 70412941 70413090 150 +      
ENSG00000082269 E002 0.0000000       6 70413421 70413424 4 +      
ENSG00000082269 E003 0.1271363 0.0124082621 0.418502189   6 70413425 70413446 22 + 0.000 0.107 9.970
ENSG00000082269 E004 0.5066574 0.0876751330 0.032935485 0.17220964 6 70413447 70413507 61 + 0.000 0.326 13.972
ENSG00000082269 E005 0.6331644 0.2279082722 0.032939458 0.17221372 6 70413508 70413513 6 + 0.000 0.380 14.095
ENSG00000082269 E006 0.5060281 0.5928224951 0.203153918 0.48570855 6 70413514 70413514 1 + 0.000 0.326 13.600
ENSG00000082269 E007 0.5060281 0.5928224951 0.203153918 0.48570855 6 70413515 70413547 33 + 0.000 0.326 13.600
ENSG00000082269 E008 0.2435110 0.0161636680 0.849430587   6 70413548 70413549 2 + 0.084 0.107 0.386
ENSG00000082269 E009 0.2435110 0.0161636680 0.849430587   6 70413550 70413565 16 + 0.084 0.107 0.386
ENSG00000082269 E010 0.2435110 0.0161636680 0.849430587   6 70413566 70413577 12 + 0.084 0.107 0.386
ENSG00000082269 E011 0.7329875 0.0306117755 0.772374773 0.91234280 6 70413578 70413645 68 + 0.215 0.265 0.386
ENSG00000082269 E012 0.9875421 0.0118712031 0.294484130 0.58790002 6 70413646 70413702 57 + 0.215 0.380 1.123
ENSG00000082269 E013 2.0681640 0.0076436830 0.821656845 0.93532993 6 70415291 70415376 86 + 0.497 0.471 -0.129
ENSG00000082269 E014 0.3637832 0.1620135760 0.775651939   6 70417280 70417295 16 + 0.155 0.107 -0.615
ENSG00000082269 E015 0.0000000       6 70418375 70418492 118 +      
ENSG00000082269 E016 1.7069889 0.0078666531 0.935566792 0.98150507 6 70426439 70426527 89 + 0.433 0.428 -0.029
ENSG00000082269 E017 0.8714471 0.0176848465 0.146258198 0.40722160 6 70426528 70426532 5 + 0.155 0.380 1.708
ENSG00000082269 E018 0.2435110 0.0161636680 0.849430587   6 70426570 70426709 140 + 0.084 0.107 0.386
ENSG00000082269 E019 0.1187032 0.0122921171 0.689496638   6 70426710 70426764 55 + 0.084 0.000 -12.593
ENSG00000082269 E020 0.0000000       6 70426765 70426771 7 +      
ENSG00000082269 E021 1.8516582 0.0168319194 0.219039858 0.50574386 6 70428304 70428342 39 + 0.359 0.546 0.971
ENSG00000082269 E022 1.3507325 0.0302535143 0.488951940 0.75202139 6 70428343 70428385 43 + 0.316 0.428 0.649
ENSG00000082269 E023 1.8198080 0.0152172240 0.768064253 0.91023462 6 70428386 70428419 34 + 0.466 0.428 -0.199
ENSG00000082269 E024 1.5566594 0.0126108364 0.122193277 0.36970561 6 70452492 70452515 24 + 0.497 0.265 -1.351
ENSG00000082269 E025 2.1557066 0.0076455488 0.056596369 0.23739840 6 70452516 70452571 56 + 0.602 0.326 -1.421
ENSG00000082269 E026 1.5413648 0.0083692022 0.003946986 0.04205388 6 70475410 70475458 49 + 0.553 0.107 -3.199
ENSG00000082269 E027 1.5422707 0.0097852271 0.004038746 0.04272768 6 70475459 70475549 91 + 0.553 0.107 -3.199
ENSG00000082269 E028 2.0568580 0.0092734931 0.474073205 0.74090776 6 70475663 70475733 71 + 0.526 0.428 -0.489
ENSG00000082269 E029 2.4003458 0.0074608020 0.081628258 0.29379636 6 70477159 70477292 134 + 0.624 0.380 -1.199
ENSG00000082269 E030 1.6595571 0.0087253782 0.002328007 0.02860760 6 70477293 70477332 40 + 0.578 0.107 -3.315
ENSG00000082269 E031 2.9106887 0.0049778990 0.524556132 0.77766276 6 70480901 70481027 127 + 0.624 0.546 -0.351
ENSG00000082269 E032 2.8474421 0.0049520600 0.040943464 0.19639317 6 70482001 70482132 132 + 0.433 0.716 1.293
ENSG00000082269 E033 1.3453466 0.0109114411 0.917579149 0.97406658 6 70482133 70482154 22 + 0.359 0.380 0.123
ENSG00000082269 E034 1.9421304 0.0074033738 0.606507033 0.82871222 6 70486167 70486244 78 + 0.497 0.428 -0.351
ENSG00000082269 E035 1.3234714 0.0559872815 0.291147565 0.58470185 6 70491034 70491083 50 + 0.433 0.265 -1.029
ENSG00000082269 E036 3.8312936 0.0065854589 0.002920095 0.03382569 6 70502636 70502791 156 + 0.817 0.428 -1.730
ENSG00000082269 E037 1.4880296 0.0107106196 0.115952384 0.35911989 6 70502792 70504960 2169 + 0.269 0.510 1.386
ENSG00000082269 E038 1.9599143 0.0072191221 0.629212646 0.84097672 6 70522513 70522586 74 + 0.433 0.510 0.386
ENSG00000082269 E039 3.6414865 0.1315187757 0.601175513 0.82553445 6 70523967 70524121 155 + 0.705 0.610 -0.403
ENSG00000082269 E040 0.0000000       6 70524122 70524342 221 +      
ENSG00000082269 E041 2.0533058 0.0985992143 0.266953627 0.56023978 6 70524343 70524837 495 + 0.553 0.380 -0.878
ENSG00000082269 E042 0.3798680 0.0185233558 0.064571830   6 70524838 70524930 93 + 0.000 0.265 13.711
ENSG00000082269 E043 6.4378758 0.0054804893 0.531042006 0.78178014 6 70524931 70525191 261 + 0.895 0.837 -0.222
ENSG00000082269 E044 7.7554930 0.0028204531 0.190859534 0.47018764 6 70525192 70525863 672 + 0.990 0.871 -0.448
ENSG00000082269 E045 20.2660750 0.0019569321 0.097093897 0.32452175 6 70525864 70526698 835 + 1.367 1.270 -0.337
ENSG00000082269 E046 6.7051700 0.0020547617 0.966894520 0.99335451 6 70528292 70528452 161 + 0.883 0.887 0.017
ENSG00000082269 E047 5.5136966 0.0077313466 0.341442653 0.63298278 6 70533160 70533251 92 + 0.757 0.871 0.450
ENSG00000082269 E048 4.2907004 0.0412504885 0.429245704 0.70758453 6 70533757 70533854 98 + 0.667 0.781 0.468
ENSG00000082269 E049 0.0000000       6 70535907 70536259 353 +      
ENSG00000082269 E050 6.4832535 0.0351962318 0.523538806 0.77675239 6 70536260 70536411 152 + 0.831 0.918 0.331
ENSG00000082269 E051 5.6304289 0.0025776200 0.406099944 0.68878249 6 70538291 70538401 111 + 0.773 0.871 0.386
ENSG00000082269 E052 0.1265070 0.0122249380 0.418815956   6 70556698 70556749 52 + 0.000 0.107 12.332
ENSG00000082269 E053 4.1620751 0.0036468625 0.479311976 0.74507759 6 70556750 70556863 114 + 0.667 0.760 0.386
ENSG00000082269 E054 0.0000000       6 70556864 70557694 831 +      
ENSG00000082269 E055 48.2151686 0.0003123516 0.012839250 0.09450964 6 70559716 70561262 1547 + 1.642 1.743 0.342

Help

Please Click HERE to learn more details about the results from DEXseq.