ENSG00000083642

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000315596 ENSG00000083642 No_inf pgKDN_inf PDS5B protein_coding protein_coding 13.78538 13.92859 14.65096 0.4062968 2.282361 0.07289466 3.131906 2.048308 3.1234513 1.1878278 1.3882837 0.6062934 0.2290000 0.150525 0.195750 0.045225 0.842418997 0.006230598 FALSE TRUE
ENST00000447833 ENSG00000083642 No_inf pgKDN_inf PDS5B protein_coding protein_coding 13.78538 13.92859 14.65096 0.4062968 2.282361 0.07289466 6.898380 6.676646 8.1269843 0.5508027 2.2894930 0.2832114 0.4824167 0.477000 0.529500 0.052500 0.862650587 0.006230598 FALSE FALSE
MSTRG.7652.3 ENSG00000083642 No_inf pgKDN_inf PDS5B protein_coding   13.78538 13.92859 14.65096 0.4062968 2.282361 0.07289466 1.809270 2.014319 2.5887568 1.1630711 1.5187203 0.3603852 0.1452083 0.141375 0.221825 0.080450 1.000000000 0.006230598 FALSE TRUE
MSTRG.7652.9 ENSG00000083642 No_inf pgKDN_inf PDS5B protein_coding   13.78538 13.92859 14.65096 0.4062968 2.282361 0.07289466 1.395874 2.932339 0.2944562 0.2260207 0.1902936 -3.2726570 0.1021250 0.212525 0.018650 -0.193875 0.006230598 0.006230598 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000083642 E001 0.0000000       13 32586452 32586454 3 +      
ENSG00000083642 E002 0.2346346 0.0155838932 2.085934e-01   13 32586455 32586532 78 + 0.181 0.000 -10.231
ENSG00000083642 E003 0.6066337 0.0147971739 5.752382e-01 0.809774683 13 32586533 32586542 10 + 0.249 0.165 -0.745
ENSG00000083642 E004 0.6066337 0.0147971739 5.752382e-01 0.809774683 13 32586543 32586547 5 + 0.249 0.165 -0.745
ENSG00000083642 E005 0.9599065 0.0122167378 1.153187e-01 0.357979193 13 32586548 32586550 3 + 0.407 0.165 -1.745
ENSG00000083642 E006 0.9599065 0.0122167378 1.153187e-01 0.357979193 13 32586551 32586568 18 + 0.407 0.165 -1.745
ENSG00000083642 E007 1.4696472 0.0126822771 8.578267e-01 0.950430842 13 32586569 32586593 25 + 0.407 0.378 -0.160
ENSG00000083642 E008 3.4301809 0.0111540120 7.910704e-01 0.919937737 13 32648754 32648880 127 + 0.665 0.628 -0.160
ENSG00000083642 E009 0.4985363 0.0152625378 3.716908e-01   13 32648881 32650617 1737 + 0.100 0.229 1.425
ENSG00000083642 E010 5.6139988 0.0082180002 3.657896e-01 0.654287446 13 32651804 32652007 204 + 0.873 0.768 -0.412
ENSG00000083642 E011 0.4890333 0.0156691670 9.178729e-01   13 32652008 32652605 598 + 0.181 0.165 -0.160
ENSG00000083642 E012 2.9247224 0.0662519949 3.547480e-01 0.644447741 13 32658239 32658325 87 + 0.665 0.521 -0.646
ENSG00000083642 E013 0.0000000       13 32658326 32658349 24 +      
ENSG00000083642 E014 2.3080251 0.0492327292 2.205272e-01 0.507484475 13 32658434 32658531 98 + 0.613 0.418 -0.938
ENSG00000083642 E015 2.5849030 0.0483087290 6.948009e-01 0.875357027 13 32659154 32659280 127 + 0.522 0.577 0.255
ENSG00000083642 E016 2.9348931 0.0057709734 8.023336e-01 0.926381986 13 32667764 32667844 81 + 0.613 0.577 -0.160
ENSG00000083642 E017 3.5217022 0.0042233963 1.159155e-01 0.359075872 13 32673216 32673356 141 + 0.753 0.550 -0.871
ENSG00000083642 E018 2.4308880 0.0063918963 2.639426e-01 0.557096184 13 32675844 32675959 116 + 0.613 0.455 -0.745
ENSG00000083642 E019 4.4035733 0.0035068741 7.576390e-01 0.904798345 13 32678835 32678929 95 + 0.753 0.713 -0.160
ENSG00000083642 E020 6.9507294 0.0118879391 3.224319e-01 0.615382716 13 32683878 32684023 146 + 0.955 0.846 -0.414
ENSG00000083642 E021 5.8456288 0.0898179950 3.356180e-01 0.627454179 13 32687134 32687285 152 + 0.902 0.768 -0.523
ENSG00000083642 E022 4.8796834 0.0140242774 3.677586e-01 0.656387546 13 32688456 32688569 114 + 0.826 0.713 -0.450
ENSG00000083642 E023 0.7445018 0.0140455603 4.888890e-01 0.752021385 13 32688570 32691268 2699 + 0.181 0.285 0.840
ENSG00000083642 E024 4.0317628 0.0105457838 6.477119e-01 0.851244129 13 32694223 32694304 82 + 0.732 0.673 -0.248
ENSG00000083642 E025 3.0350235 0.0364521469 2.522862e-01 0.543784557 13 32696854 32696902 49 + 0.688 0.521 -0.745
ENSG00000083642 E026 4.4047297 0.0445284247 8.058778e-01 0.928100981 13 32699730 32699869 140 + 0.752 0.713 -0.159
ENSG00000083642 E027 0.0000000       13 32700984 32701322 339 +      
ENSG00000083642 E028 5.4159653 0.0029288464 5.770868e-01 0.810946954 13 32701323 32701438 116 + 0.772 0.832 0.236
ENSG00000083642 E029 5.2981462 0.0026545983 4.689770e-01 0.737018746 13 32706934 32707039 106 + 0.753 0.832 0.314
ENSG00000083642 E030 6.8258016 0.0220405389 1.861642e-01 0.463995337 13 32709946 32710106 161 + 0.968 0.817 -0.575
ENSG00000083642 E031 5.9783906 0.0024028424 2.829477e-01 0.576629636 13 32732101 32732224 124 + 0.902 0.785 -0.456
ENSG00000083642 E032 8.5046849 0.0016174936 3.490445e-02 0.178710512 13 32735172 32735330 159 + 1.074 0.874 -0.745
ENSG00000083642 E033 4.4836586 0.0114971359 4.087645e-02 0.196193847 13 32741080 32741102 23 + 0.858 0.603 -1.045
ENSG00000083642 E034 5.8185241 0.0150458228 2.610921e-02 0.149413160 13 32741103 32741148 46 + 0.955 0.693 -1.027
ENSG00000083642 E035 10.5620665 0.0045064940 8.786204e-01 0.958918009 13 32742591 32742727 137 + 1.055 1.066 0.041
ENSG00000083642 E036 9.4823945 0.0026325605 4.318836e-01 0.709488338 13 32745977 32746100 124 + 0.979 1.049 0.255
ENSG00000083642 E037 16.4819906 0.0010127773 5.415611e-01 0.789225461 13 32753332 32753536 205 + 1.218 1.258 0.142
ENSG00000083642 E038 11.8694915 0.0012678577 4.125791e-01 0.693757135 13 32755842 32755956 115 + 1.144 1.075 -0.250
ENSG00000083642 E039 8.1029600 0.0018803680 9.463696e-01 0.985664316 13 32758087 32758168 82 + 0.955 0.959 0.015
ENSG00000083642 E040 6.1321838 0.0025560282 9.314171e-01 0.979992008 13 32758169 32758219 51 + 0.858 0.846 -0.045
ENSG00000083642 E041 11.5995028 0.0012341333 2.191274e-01 0.505795539 13 32758534 32758653 120 + 1.152 1.049 -0.373
ENSG00000083642 E042 8.9553634 0.0015836757 9.255569e-01 0.977650045 13 32759628 32759690 63 + 1.002 0.991 -0.042
ENSG00000083642 E043 15.2799819 0.0019645778 1.631243e-01 0.431773576 13 32760575 32760720 146 + 1.152 1.253 0.357
ENSG00000083642 E044 9.0328431 0.0143222815 6.723229e-02 0.261515071 13 32764489 32764588 100 + 0.888 1.075 0.694
ENSG00000083642 E045 2.4847913 0.0066528665 1.174722e-01 0.362063281 13 32764589 32764594 6 + 0.407 0.628 1.062
ENSG00000083642 E046 9.6870217 0.0013827712 9.000703e-01 0.967540101 13 32770121 32770189 69 + 1.035 1.021 -0.051
ENSG00000083642 E047 36.2576168 0.0104174415 6.008601e-01 0.825314074 13 32770190 32770560 371 + 1.589 1.553 -0.121
ENSG00000083642 E048 0.6253903 0.0141652962 2.109144e-01 0.495727364 13 32770651 32770653 3 + 0.100 0.285 1.840
ENSG00000083642 E049 11.6658510 0.0250517982 9.044834e-01 0.969288339 13 32770654 32770761 108 + 1.093 1.107 0.052
ENSG00000083642 E050 0.1265070 0.0123093784 5.971820e-01   13 32770762 32770878 117 + 0.000 0.090 10.770
ENSG00000083642 E051 0.1170040 0.0116684280 4.843053e-01   13 32770879 32771079 201 + 0.100 0.000 -11.921
ENSG00000083642 E052 12.1017906 0.0132198362 1.269085e-01 0.377616731 13 32773189 32773324 136 + 1.035 1.173 0.499
ENSG00000083642 E053 80.6587439 0.0002615137 6.039088e-05 0.001554712 13 32775017 32778019 3003 + 1.841 1.960 0.403

Help

Please Click HERE to learn more details about the results from DEXseq.