ENSG00000084070

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372708 ENSG00000084070 No_inf pgKDN_inf SMAP2 protein_coding protein_coding 676.9734 459.6022 747.373 7.738111 5.870739 0.7014306 322.28018 250.23306 349.96844 4.728262 11.044716 0.483936 0.48601667 0.544825 0.468250 -0.076575 7.099989e-02 1.806353e-09 FALSE TRUE
ENST00000372718 ENSG00000084070 No_inf pgKDN_inf SMAP2 protein_coding protein_coding 676.9734 459.6022 747.373 7.738111 5.870739 0.7014306 304.52333 150.52343 354.37486 4.697553 7.670965 1.235233 0.43253333 0.327325 0.474175 0.146850 1.806353e-09 1.806353e-09 FALSE TRUE
ENST00000487871 ENSG00000084070 No_inf pgKDN_inf SMAP2 protein_coding protein_coding_CDS_not_defined 676.9734 459.6022 747.373 7.738111 5.870739 0.7014306 47.36974 53.79983 41.03908 7.099541 4.283501 -0.390520 0.07621667 0.116500 0.054925 -0.061575 8.059641e-03 1.806353e-09   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000084070 E001 0.0000000       1 40344850 40344910 61 +      
ENSG00000084070 E002 0.4884040 1.578848e-02 6.386826e-01   1 40362300 40362436 137 + 0.139 0.213 0.744
ENSG00000084070 E003 459.8842975 4.199082e-04 2.765867e-12 3.421428e-10 1 40373727 40374223 497 + 2.689 2.590 -0.329
ENSG00000084070 E004 4.1085418 3.511560e-03 4.723291e-01 7.396398e-01 1 40374648 40374708 61 + 0.728 0.652 -0.319
ENSG00000084070 E005 0.7446278 1.356132e-01 2.134195e-01 4.986598e-01 1 40393345 40393504 160 + 0.139 0.356 1.745
ENSG00000084070 E006 0.7352171 1.428377e-02 5.664595e-01 8.046954e-01 1 40396800 40396890 91 + 0.195 0.290 0.745
ENSG00000084070 E007 386.2535817 5.798087e-05 3.770968e-04 6.974739e-03 1 40406736 40406869 134 + 2.592 2.554 -0.128
ENSG00000084070 E008 375.8379389 7.561347e-04 1.657301e-02 1.121148e-01 1 40408653 40408738 86 + 2.576 2.548 -0.094
ENSG00000084070 E009 361.4395307 3.438890e-04 5.055448e-04 8.823364e-03 1 40409757 40409835 79 + 2.565 2.521 -0.147
ENSG00000084070 E010 410.8525600 6.505543e-05 2.061594e-06 8.727630e-05 1 40413016 40413102 87 + 2.625 2.569 -0.185
ENSG00000084070 E011 27.4304466 1.102354e-03 3.290170e-12 4.014752e-10 1 40413977 40414158 182 + 1.227 1.651 1.461
ENSG00000084070 E012 419.4981971 1.516800e-03 1.280951e-03 1.810926e-02 1 40414159 40414240 82 + 2.633 2.580 -0.177
ENSG00000084070 E013 474.3977713 6.341646e-05 6.140883e-05 1.572661e-03 1 40415272 40415381 110 + 2.682 2.642 -0.131
ENSG00000084070 E014 636.9794790 6.296138e-05 1.894217e-05 5.884949e-04 1 40416176 40416341 166 + 2.808 2.773 -0.116
ENSG00000084070 E015 778.5971248 3.020294e-04 6.580132e-06 2.372278e-04 1 40416780 40417096 317 + 2.896 2.857 -0.131
ENSG00000084070 E016 4163.6507763 2.711287e-04 6.106642e-37 4.915756e-34 1 40421976 40423326 1351 + 3.576 3.657 0.269

Help

Please Click HERE to learn more details about the results from DEXseq.