ENSG00000084073

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372759 ENSG00000084073 No_inf pgKDN_inf ZMPSTE24 protein_coding protein_coding 550.9778 323.209 689.2933 4.492977 5.389165 1.092627 399.34280 206.52488 504.06878 1.131995 3.171021 1.2872638 0.71060000 0.639225 0.731400 0.092175 5.521316e-05 5.521316e-05 FALSE  
ENST00000474142 ENSG00000084073 No_inf pgKDN_inf ZMPSTE24 protein_coding retained_intron 550.9778 323.209 689.2933 4.492977 5.389165 1.092627 76.14970 73.01641 90.87124 3.901944 6.716159 0.3155642 0.15267500 0.225575 0.131675 -0.093900 1.171663e-03 5.521316e-05 FALSE  
ENST00000674703 ENSG00000084073 No_inf pgKDN_inf ZMPSTE24 protein_coding nonsense_mediated_decay 550.9778 323.209 689.2933 4.492977 5.389165 1.092627 42.42686 20.81071 56.98634 1.562692 4.656976 1.4528500 0.07485000 0.064625 0.082625 0.018000 6.480670e-01 5.521316e-05 FALSE  
ENST00000675937 ENSG00000084073 No_inf pgKDN_inf ZMPSTE24 protein_coding nonsense_mediated_decay 550.9778 323.209 689.2933 4.492977 5.389165 1.092627 27.92297 16.78707 33.74989 1.330157 3.801502 1.0071005 0.05089167 0.051825 0.049000 -0.002825 9.372689e-01 5.521316e-05 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000084073 E001 0.0000000       1 40258041 40258090 50 +      
ENSG00000084073 E002 50.9606715 2.618346e-04 8.329432e-01 9.397571e-01 1 40258091 40258235 145 + 1.693 1.703 0.032
ENSG00000084073 E003 47.9399263 2.824538e-04 8.750282e-01 9.573161e-01 1 40258236 40258238 3 + 1.668 1.675 0.024
ENSG00000084073 E004 276.1294539 7.387334e-05 1.155760e-04 2.677610e-03 1 40258239 40258394 156 + 2.448 2.373 -0.251
ENSG00000084073 E005 3.3120188 2.725490e-02 7.653758e-02 2.828874e-01 1 40259350 40259532 183 + 0.514 0.764 1.082
ENSG00000084073 E006 371.1964775 1.085422e-04 3.939162e-06 1.530654e-04 1 40260839 40260985 147 + 2.578 2.499 -0.262
ENSG00000084073 E007 0.0000000       1 40262834 40262983 150 +      
ENSG00000084073 E008 2.3587594 7.215721e-03 2.418244e-03 2.938175e-02 1 40267391 40267507 117 + 0.311 0.737 2.091
ENSG00000084073 E009 251.6941680 8.129273e-05 1.479135e-04 3.268155e-03 1 40267786 40267872 87 + 2.409 2.331 -0.259
ENSG00000084073 E010 310.1406897 8.104795e-04 4.165609e-03 4.372674e-02 1 40268419 40268535 117 + 2.494 2.433 -0.206
ENSG00000084073 E011 413.9112615 1.344391e-03 6.721969e-02 2.615151e-01 1 40269975 40270127 153 + 2.612 2.573 -0.132
ENSG00000084073 E012 399.6511974 5.373823e-05 2.777840e-01 5.710310e-01 1 40271894 40272035 142 + 2.589 2.572 -0.057
ENSG00000084073 E013 20.5170347 2.190400e-03 1.076598e-03 1.584317e-02 1 40280120 40280312 193 + 1.223 1.444 0.769
ENSG00000084073 E014 490.5523920 3.636929e-04 1.379736e-01 3.953180e-01 1 40281343 40281527 185 + 2.664 2.687 0.079
ENSG00000084073 E015 400.5453197 7.258722e-05 7.847979e-01 9.170041e-01 1 40285925 40286029 105 + 2.583 2.587 0.015
ENSG00000084073 E016 0.9820341 3.029269e-01 4.717396e-01 7.390578e-01 1 40290645 40290853 209 + 0.230 0.375 0.974
ENSG00000084073 E017 495.7798166 4.348468e-05 6.133172e-01 8.318488e-01 1 40290854 40290997 144 + 2.674 2.681 0.024
ENSG00000084073 E018 4539.2560179 2.761694e-05 1.886575e-08 1.273473e-06 1 40292445 40294180 1736 + 3.631 3.649 0.061

Help

Please Click HERE to learn more details about the results from DEXseq.