ENSG00000084733

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264710 ENSG00000084733 No_inf pgKDN_inf RAB10 protein_coding protein_coding 67.72 60.76443 79.90768 1.188986 1.615504 0.3950502 61.01536 40.65051 79.90768 1.979591 1.615504 0.9748863 0.890025 0.670075 1 0.329925 2.858156e-45 2.858156e-45 FALSE TRUE
ENST00000473035 ENSG00000084733 No_inf pgKDN_inf RAB10 protein_coding protein_coding_CDS_not_defined 67.72 60.76443 79.90768 1.188986 1.615504 0.3950502 6.70464 20.11392 0.00000 2.473259 0.000000 -10.9746956 0.109975 0.329925 0 -0.329925 2.931263e-26 2.858156e-45 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000084733 E001 0.9616733 1.168699e-02 2.668397e-01 5.601987e-01 2 26034084 26034106 23 + 0.363 0.191 -1.243
ENSG00000084733 E002 157.7878216 1.262663e-04 2.155770e-06 9.055240e-05 2 26034107 26034735 629 + 2.247 2.136 -0.369
ENSG00000084733 E003 0.3709916 1.659820e-02 4.475784e-01   2 26098530 26098577 48 + 0.085 0.191 1.342
ENSG00000084733 E004 47.6088716 6.429620e-04 2.194046e-04 4.511387e-03 2 26098662 26098722 61 + 1.753 1.588 -0.560
ENSG00000084733 E005 80.9088946 1.829159e-04 1.133545e-04 2.631795e-03 2 26109768 26109906 139 + 1.966 1.838 -0.433
ENSG00000084733 E006 67.6461823 2.287886e-04 8.728360e-01 9.565454e-01 2 26127144 26127233 90 + 1.838 1.832 -0.018
ENSG00000084733 E007 0.1176306 1.182215e-02 6.797035e-01   2 26127234 26127278 45 + 0.085 0.000 -7.908
ENSG00000084733 E008 89.5838348 1.861754e-04 7.461088e-01 8.995938e-01 2 26127850 26127951 102 + 1.960 1.950 -0.033
ENSG00000084733 E009 875.6075910 4.689382e-05 2.936114e-12 3.623716e-10 2 26134938 26137454 2517 + 2.921 2.964 0.142

Help

Please Click HERE to learn more details about the results from DEXseq.