ENSG00000084754

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000380649 ENSG00000084754 No_inf pgKDN_inf HADHA protein_coding protein_coding 71.16467 56.15952 79.50213 1.024136 1.149545 0.5013874 25.079049 17.109329 28.7805789 2.163166 2.6642577 0.7499707 0.34756667 0.304275 0.361925 0.057650 0.81623491 0.02944595 FALSE  
ENST00000643233 ENSG00000084754 No_inf pgKDN_inf HADHA protein_coding nonsense_mediated_decay 71.16467 56.15952 79.50213 1.024136 1.149545 0.5013874 37.273834 24.813296 46.4577477 3.177164 2.9977548 0.9045350 0.51547500 0.441675 0.584550 0.142875 0.39127553 0.02944595 FALSE  
ENST00000646031 ENSG00000084754 No_inf pgKDN_inf HADHA protein_coding nonsense_mediated_decay 71.16467 56.15952 79.50213 1.024136 1.149545 0.5013874 2.200188 4.717012 0.5074501 1.510006 0.1744748 -3.1914371 0.03565833 0.082900 0.006400 -0.076500 0.02944595 0.02944595 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000084754 E001 0.7431496 0.0139570802 2.481217e-01 0.538952677 2 26190635 26190654 20 - 0.154 0.328 1.407
ENSG00000084754 E002 1.6041820 0.0083768464 1.853749e-01 0.463124391 2 26190655 26190670 16 - 0.314 0.513 1.085
ENSG00000084754 E003 8.7449456 0.0016767114 4.823168e-01 0.747240292 2 26190671 26190880 210 - 1.015 0.949 -0.245
ENSG00000084754 E004 7.0923079 0.0021848564 4.264311e-01 0.705043411 2 26190881 26190888 8 - 0.868 0.949 0.308
ENSG00000084754 E005 15.6376532 0.0156332724 4.712756e-01 0.738695653 2 26190889 26190921 33 - 1.189 1.253 0.226
ENSG00000084754 E006 47.4797427 0.0003262372 2.740908e-01 0.567635484 2 26190922 26191058 137 - 1.661 1.709 0.162
ENSG00000084754 E007 104.7267614 0.0002021721 3.646336e-04 0.006809608 2 26191059 26191249 191 - 1.973 2.076 0.346
ENSG00000084754 E008 106.9080353 0.0001836449 6.371491e-01 0.845154933 2 26191250 26191395 146 - 2.024 2.038 0.047
ENSG00000084754 E009 1.2515061 0.0099296050 1.783844e-02 0.117615921 2 26191396 26191482 87 - 0.154 0.513 2.407
ENSG00000084754 E010 95.4811217 0.0009606546 1.973544e-01 0.478623592 2 26191483 26191628 146 - 1.963 2.005 0.141
ENSG00000084754 E011 72.4128952 0.0004353251 3.661360e-01 0.654747369 2 26192310 26192424 115 - 1.877 1.845 -0.108
ENSG00000084754 E012 78.9045627 0.0070372193 5.704751e-01 0.806987246 2 26193577 26193772 196 - 1.888 1.915 0.089
ENSG00000084754 E013 39.5819483 0.0003497776 8.642602e-02 0.304603270 2 26194570 26194638 69 - 1.641 1.559 -0.278
ENSG00000084754 E014 73.5227466 0.0048090857 6.579507e-01 0.856980219 2 26195092 26195232 141 - 1.879 1.859 -0.065
ENSG00000084754 E015 54.8214448 0.0036909174 1.931665e-01 0.472975874 2 26197691 26197777 87 - 1.716 1.777 0.208
ENSG00000084754 E016 0.3625611 0.0166266153 7.726135e-01   2 26199243 26199366 124 - 0.154 0.108 -0.593
ENSG00000084754 E017 82.7536920 0.0002473141 8.775757e-01 0.958435138 2 26201149 26201320 172 - 1.918 1.924 0.018
ENSG00000084754 E018 70.1347929 0.0012850583 6.494750e-01 0.852316023 2 26204062 26204196 135 - 1.842 1.859 0.059
ENSG00000084754 E019 61.9205559 0.0002640695 8.928963e-01 0.964501975 2 26209780 26209889 110 - 1.794 1.799 0.018
ENSG00000084754 E020 1.7382454 0.0308526465 4.131230e-02 0.197372467 2 26210545 26210694 150 - 0.267 0.582 1.729
ENSG00000084754 E021 3.2478335 0.0043419074 5.025260e-04 0.008783816 2 26210695 26210814 120 - 0.357 0.822 2.144
ENSG00000084754 E022 6.4637088 0.0081217046 9.124974e-05 0.002201997 2 26211937 26212569 633 - 0.622 1.058 1.710
ENSG00000084754 E023 45.0490506 0.0003283609 7.397902e-01 0.896869909 2 26212570 26212626 57 - 1.667 1.653 -0.049
ENSG00000084754 E024 59.6943621 0.0002948639 1.917632e-01 0.471477804 2 26214443 26214561 119 - 1.803 1.752 -0.171
ENSG00000084754 E025 0.2542726 0.2679135667 2.121574e-01   2 26214562 26214576 15 - 0.000 0.194 11.330
ENSG00000084754 E026 59.7955592 0.0002761816 1.263625e-01 0.376869143 2 26215053 26215175 123 - 1.807 1.748 -0.200
ENSG00000084754 E027 44.7401211 0.0003236611 1.930534e-01 0.472857102 2 26230192 26230294 103 - 1.683 1.625 -0.198
ENSG00000084754 E028 26.1511389 0.0156180342 5.564967e-01 0.798735801 2 26232160 26232201 42 - 1.450 1.407 -0.150
ENSG00000084754 E029 34.1436651 0.0004424534 2.340063e-01 0.523052791 2 26232202 26232279 78 - 1.570 1.509 -0.208
ENSG00000084754 E030 48.6100372 0.0103577051 4.329482e-01 0.710436477 2 26234217 26234355 139 - 1.714 1.666 -0.162
ENSG00000084754 E031 0.3802150 0.0272941608 6.072794e-02   2 26235091 26235304 214 - 0.000 0.266 11.915
ENSG00000084754 E032 44.6153367 0.0003049837 9.696784e-03 0.078786736 2 26236855 26236988 134 - 1.705 1.588 -0.397
ENSG00000084754 E033 27.2788675 0.0097404007 5.933510e-02 0.244419089 2 26238934 26239004 71 - 1.503 1.372 -0.451
ENSG00000084754 E034 20.8822233 0.0120912173 3.082106e-01 0.601382656 2 26239102 26239143 42 - 1.372 1.292 -0.276
ENSG00000084754 E035 0.0000000       2 26244525 26244529 5 -      
ENSG00000084754 E036 19.0359505 0.0024557587 1.371739e-01 0.394262664 2 26244530 26244672 143 - 1.343 1.239 -0.364

Help

Please Click HERE to learn more details about the results from DEXseq.