ENSG00000085511

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000348824 ENSG00000085511 No_inf pgKDN_inf MAP3K4 protein_coding protein_coding 18.37145 19.64886 16.13211 2.797595 1.423826 -0.2843507 3.087388 3.2824317 2.944513 0.3315651 1.2789365 -0.1562334 0.1797833 0.181275 0.199225 0.017950 0.98299233 0.01478068 FALSE TRUE
ENST00000366920 ENSG00000085511 No_inf pgKDN_inf MAP3K4 protein_coding protein_coding 18.37145 19.64886 16.13211 2.797595 1.423826 -0.2843507 3.490800 0.9284366 4.911490 0.6187091 0.7551597 2.3907642 0.1978167 0.039850 0.309625 0.269775 0.01478068 0.01478068 FALSE TRUE
ENST00000536852 ENSG00000085511 No_inf pgKDN_inf MAP3K4 protein_coding retained_intron 18.37145 19.64886 16.13211 2.797595 1.423826 -0.2843507 2.141627 3.2030900 0.451308 0.5039929 0.2724505 -2.8001593 0.1130250 0.170650 0.024350 -0.146300 0.05996895 0.01478068 FALSE TRUE
ENST00000539610 ENSG00000085511 No_inf pgKDN_inf MAP3K4 protein_coding retained_intron 18.37145 19.64886 16.13211 2.797595 1.423826 -0.2843507 2.714375 6.4514082 1.691716 2.8470600 1.0141878 -1.9248582 0.1250750 0.283825 0.091400 -0.192425 0.67878842 0.01478068   FALSE
ENST00000542851 ENSG00000085511 No_inf pgKDN_inf MAP3K4 protein_coding retained_intron 18.37145 19.64886 16.13211 2.797595 1.423826 -0.2843507 1.155061 1.5455432 0.729564 0.5254274 0.7295640 -1.0726716 0.0651500 0.087300 0.048575 -0.038725 0.50354330 0.01478068 FALSE FALSE
MSTRG.25629.10 ENSG00000085511 No_inf pgKDN_inf MAP3K4 protein_coding   18.37145 19.64886 16.13211 2.797595 1.423826 -0.2843507 3.649708 2.1061257 3.729257 0.3705753 0.5128278 0.8213263 0.2057500 0.122525 0.229200 0.106675 0.52402483 0.01478068 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000085511 E001 0.0000000       6 160991727 160991768 42 +      
ENSG00000085511 E002 0.0000000       6 160991769 160991813 45 +      
ENSG00000085511 E003 0.0000000       6 160991814 160991843 30 +      
ENSG00000085511 E004 0.0000000       6 160991844 160992083 240 +      
ENSG00000085511 E005 0.1271363 0.0123072426 0.4215257219   6 161022194 161022227 34 + 0.000 0.106 10.723
ENSG00000085511 E006 0.2356421 0.0156780866 0.3361516473   6 161034083 161034118 36 + 0.157 0.000 -11.293
ENSG00000085511 E007 0.8431848 0.0129787894 0.4049913428 0.68770238 6 161034259 161034273 15 + 0.320 0.191 -0.982
ENSG00000085511 E008 3.1120601 0.0045819962 0.0082703523 0.07071230 6 161034274 161034357 84 + 0.746 0.376 -1.731
ENSG00000085511 E009 3.9657996 0.0038065180 0.0193244038 0.12421745 6 161034358 161034449 92 + 0.809 0.506 -1.304
ENSG00000085511 E010 0.0000000       6 161048246 161048291 46 +      
ENSG00000085511 E011 18.9304754 0.0123494351 0.0006540942 0.01075546 6 161048616 161049340 725 + 1.404 1.127 -0.976
ENSG00000085511 E012 24.0205581 0.0006586972 0.0263689702 0.15051159 6 161049341 161049979 639 + 1.454 1.319 -0.468
ENSG00000085511 E013 0.0000000       6 161067199 161067296 98 +      
ENSG00000085511 E014 12.1986126 0.0014426836 0.0061193799 0.05730902 6 161070608 161070850 243 + 1.210 0.979 -0.836
ENSG00000085511 E015 1.3866985 0.0111568419 0.0011535798 0.01671157 6 161073329 161073465 137 + 0.086 0.574 3.661
ENSG00000085511 E016 9.3053463 0.0015108099 0.0212032464 0.13171802 6 161073466 161073612 147 + 1.098 0.881 -0.803
ENSG00000085511 E017 0.3727544 0.0168252103 0.4447385212   6 161080683 161080880 198 + 0.086 0.191 1.340
ENSG00000085511 E018 10.8663535 0.0236901323 0.0242146849 0.14257518 6 161080881 161081038 158 + 1.168 0.926 -0.883
ENSG00000085511 E019 8.8753887 0.0021718546 0.6188582634 0.83520330 6 161084501 161084617 117 + 1.015 0.967 -0.180
ENSG00000085511 E020 7.6690885 0.0416912218 0.9536717664 0.98857873 6 161086379 161086478 100 + 0.946 0.926 -0.075
ENSG00000085511 E021 7.0476029 0.0591171577 0.5873015428 0.81690369 6 161086584 161086667 84 + 0.935 0.865 -0.266
ENSG00000085511 E022 14.6270789 0.0010707421 0.9717133477 0.99463642 6 161087688 161087954 267 + 1.193 1.193 0.001
ENSG00000085511 E023 11.0476055 0.0017616515 0.0775182003 0.28485839 6 161089322 161089471 150 + 1.006 1.153 0.532
ENSG00000085511 E024 11.9253362 0.0223538190 0.5074883079 0.76588653 6 161091379 161091540 162 + 1.141 1.070 -0.258
ENSG00000085511 E025 15.6279360 0.0009548578 0.7641187300 0.90819295 6 161092010 161092143 134 + 1.210 1.230 0.068
ENSG00000085511 E026 12.8391658 0.0012107509 0.3468989970 0.63755369 6 161092978 161093056 79 + 1.106 1.177 0.257
ENSG00000085511 E027 10.9355084 0.0013137203 0.4414772953 0.71696150 6 161093773 161093839 67 + 1.106 1.038 -0.245
ENSG00000085511 E028 1.9500305 0.0070257975 0.9841318527 0.99872794 6 161093840 161093851 12 + 0.471 0.466 -0.023
ENSG00000085511 E029 1.0894973 0.0107592648 0.5181317850 0.77339052 6 161096697 161097079 383 + 0.363 0.262 -0.660
ENSG00000085511 E030 11.0301578 0.0013252098 0.1333029075 0.38780727 6 161097080 161097165 86 + 1.134 1.004 -0.474
ENSG00000085511 E031 4.7257820 0.0032636052 0.3073956024 0.60061663 6 161097166 161097176 11 + 0.809 0.686 -0.497
ENSG00000085511 E032 0.1271363 0.0123072426 0.4215257219   6 161098240 161098277 38 + 0.000 0.106 10.867
ENSG00000085511 E033 3.1185175 0.0075585056 0.0286702729 0.15855786 6 161098278 161098427 150 + 0.728 0.424 -1.397
ENSG00000085511 E034 2.1220452 0.0067964855 0.0070065601 0.06306964 6 161101033 161101891 859 + 0.272 0.661 2.040
ENSG00000085511 E035 10.6128479 0.0013556977 0.8782925378 0.95866555 6 161101892 161101992 101 + 1.059 1.070 0.040
ENSG00000085511 E036 9.1508093 0.0015194792 0.8177712999 0.93365800 6 161102699 161102779 81 + 0.997 1.015 0.069
ENSG00000085511 E037 18.6519421 0.0008628362 0.0313510455 0.16711608 6 161106514 161106705 192 + 1.222 1.362 0.492
ENSG00000085511 E038 9.3660263 0.0266199325 0.0401084813 0.19411949 6 161107899 161107969 71 + 0.901 1.118 0.799
ENSG00000085511 E039 11.8832116 0.0011462369 0.1973281497 0.47858155 6 161108743 161108859 117 + 1.059 1.161 0.369
ENSG00000085511 E040 0.8615058 0.0128763781 0.4905028154 0.75310322 6 161108860 161108878 19 + 0.218 0.322 0.755
ENSG00000085511 E041 1.2346999 0.0111083590 0.3161528086 0.60904331 6 161108879 161108950 72 + 0.272 0.424 0.924
ENSG00000085511 E042 2.4792509 0.0602529605 0.1063397352 0.34140885 6 161108951 161109041 91 + 0.402 0.661 1.233
ENSG00000085511 E043 15.3526828 0.0010818179 0.0192805877 0.12409921 6 161109755 161109914 160 + 1.127 1.295 0.594
ENSG00000085511 E044 15.1423302 0.0038190548 0.5468134887 0.79245052 6 161111836 161111958 123 + 1.186 1.230 0.153
ENSG00000085511 E045 18.1358412 0.0008324448 0.0701457682 0.26808687 6 161112668 161112774 107 + 1.222 1.341 0.418
ENSG00000085511 E046 27.4365906 0.0021750609 0.0566644431 0.23757308 6 161115123 161115302 180 + 1.401 1.507 0.365
ENSG00000085511 E047 39.1314133 0.0003681151 0.1544113420 0.41983272 6 161116850 161117436 587 + 1.572 1.635 0.213

Help

Please Click HERE to learn more details about the results from DEXseq.