ENSG00000085563

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265724 ENSG00000085563 No_inf pgKDN_inf ABCB1 protein_coding protein_coding 6.650353 5.010651 8.703874 0.1992524 0.9545456 0.7954398 1.2911009 0.0000000 2.6633949 0.0000000 0.5016604 8.0625292 0.20172500 0.0000 0.314250 0.314250 0.0004434844 0.0004434844 FALSE TRUE
ENST00000482527 ENSG00000085563 No_inf pgKDN_inf ABCB1 protein_coding retained_intron 6.650353 5.010651 8.703874 0.1992524 0.9545456 0.7954398 0.5995397 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.06910833 0.0000 0.000000 0.000000   0.0004434844 FALSE FALSE
ENST00000488737 ENSG00000085563 No_inf pgKDN_inf ABCB1 protein_coding protein_coding_CDS_not_defined 6.650353 5.010651 8.703874 0.1992524 0.9545456 0.7954398 2.7526450 2.5440728 3.6832820 0.1496667 0.2147120 0.5321038 0.41035000 0.5069 0.430850 -0.076050 0.8354345921 0.0004434844 FALSE TRUE
ENST00000491360 ENSG00000085563 No_inf pgKDN_inf ABCB1 protein_coding retained_intron 6.650353 5.010651 8.703874 0.1992524 0.9545456 0.7954398 0.3103745 0.0000000 0.9311236 0.0000000 0.9311236 6.5563123 0.02695833 0.0000 0.080875 0.080875 0.8836085338 0.0004434844   FALSE
ENST00000543898 ENSG00000085563 No_inf pgKDN_inf ABCB1 protein_coding protein_coding 6.650353 5.010651 8.703874 0.1992524 0.9545456 0.7954398 0.1145412 0.3436237 0.0000000 0.3436237 0.0000000 -5.1441430 0.02156667 0.0647 0.000000 -0.064700 0.8150444790 0.0004434844 FALSE TRUE
ENST00000622132 ENSG00000085563 No_inf pgKDN_inf ABCB1 protein_coding protein_coding 6.650353 5.010651 8.703874 0.1992524 0.9545456 0.7954398 1.5821520 2.1229549 1.4260738 0.2535153 0.3755364 -0.5707236 0.27029167 0.4284 0.174000 -0.254400 0.3007110757 0.0004434844 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000085563 E001 5.9483486 0.029467036 0.003110333 0.03544321 7 87503017 87503858 842 - 0.639 1.006 1.446
ENSG00000085563 E002 1.3496577 0.018196613 0.427878806 0.70640253 7 87503859 87503862 4 - 0.311 0.434 0.710
ENSG00000085563 E003 1.3496577 0.018196613 0.427878806 0.70640253 7 87503863 87503863 1 - 0.311 0.434 0.710
ENSG00000085563 E004 10.1149098 0.014188625 0.720765503 0.88752219 7 87503864 87504155 292 - 1.027 1.063 0.133
ENSG00000085563 E005 12.4415608 0.002978443 0.737798615 0.89591758 7 87504156 87504449 294 - 1.112 1.142 0.105
ENSG00000085563 E006 2.0630071 0.008519819 0.549823857 0.79452884 7 87505897 87505901 5 - 0.519 0.434 -0.428
ENSG00000085563 E007 10.3566024 0.001676187 0.979120265 0.99739001 7 87505902 87506043 142 - 1.052 1.053 0.002
ENSG00000085563 E008 0.1186381 0.011953420 0.727499739   7 87506044 87506141 98 - 0.083 0.000 -9.970
ENSG00000085563 E009 10.3813643 0.001422301 0.518212017 0.77344606 7 87509275 87509481 207 - 1.027 1.084 0.208
ENSG00000085563 E010 0.0000000       7 87515228 87515230 3 -      
ENSG00000085563 E011 8.3578542 0.002994640 0.046586310 0.21180022 7 87515231 87515428 198 - 0.875 1.063 0.702
ENSG00000085563 E012 8.5313274 0.026298261 0.802588678 0.92647613 7 87516509 87516665 157 - 0.963 0.994 0.115
ENSG00000085563 E013 0.0000000       7 87518881 87518963 83 -      
ENSG00000085563 E014 6.4466176 0.002264922 0.885290709 0.96140658 7 87519326 87519466 141 - 0.875 0.862 -0.048
ENSG00000085563 E015 4.4932515 0.003158774 0.565391092 0.80429811 7 87520776 87520876 101 - 0.765 0.699 -0.270
ENSG00000085563 E016 0.1272623 0.012413055 0.394744347   7 87520877 87521119 243 - 0.000 0.109 10.757
ENSG00000085563 E017 5.3222793 0.002959126 0.145252502 0.40552757 7 87531294 87531497 204 - 0.863 0.699 -0.653
ENSG00000085563 E018 0.0000000       7 87531575 87531697 123 -      
ENSG00000085563 E019 2.0635986 0.028982141 0.568338514 0.80586717 7 87536458 87536541 84 - 0.519 0.434 -0.428
ENSG00000085563 E020 0.0000000       7 87537038 87537062 25 -      
ENSG00000085563 E021 3.1766089 0.010179926 0.708276768 0.88176951 7 87539268 87539345 78 - 0.595 0.646 0.224
ENSG00000085563 E022 4.6265627 0.014430561 0.967396532 0.99341205 7 87541357 87541464 108 - 0.749 0.746 -0.013
ENSG00000085563 E023 4.9835201 0.058149850 0.688727020 0.87178303 7 87544129 87544275 147 - 0.795 0.746 -0.197
ENSG00000085563 E024 6.0948306 0.004042451 0.831613877 0.93923908 7 87544823 87544999 177 - 0.837 0.862 0.099
ENSG00000085563 E025 3.2568930 0.005102950 0.170456489 0.44263418 7 87545863 87545948 86 - 0.698 0.517 -0.802
ENSG00000085563 E026 2.4031540 0.005887300 0.105527500 0.33987341 7 87545949 87546024 76 - 0.618 0.385 -1.139
ENSG00000085563 E027 4.6042468 0.003717486 0.478345796 0.74434585 7 87549348 87549518 171 - 0.780 0.699 -0.331
ENSG00000085563 E028 5.4449732 0.002661354 0.207549807 0.49111531 7 87549851 87550054 204 - 0.863 0.723 -0.554
ENSG00000085563 E029 0.0000000       7 87550055 87550158 104 -      
ENSG00000085563 E030 2.7881560 0.015179557 0.467372028 0.73578024 7 87550171 87550296 126 - 0.618 0.517 -0.461
ENSG00000085563 E031 1.5951498 0.008531066 0.413165935 0.69404210 7 87550468 87550578 111 - 0.354 0.477 0.669
ENSG00000085563 E032 2.3097558 0.056087419 0.961179812 0.99139935 7 87550725 87550838 114 - 0.519 0.517 -0.013
ENSG00000085563 E033 2.9087072 0.015466545 0.636706431 0.84488564 7 87553761 87553932 172 - 0.618 0.553 -0.290
ENSG00000085563 E034 2.5667002 0.005961328 0.635700761 0.84454861 7 87561263 87561387 125 - 0.519 0.586 0.309
ENSG00000085563 E035 5.8058997 0.002435635 0.192532255 0.47240957 7 87566070 87566241 172 - 0.887 0.746 -0.554
ENSG00000085563 E036 5.2304181 0.057281340 0.734479478 0.89461997 7 87566785 87566976 192 - 0.810 0.768 -0.166
ENSG00000085563 E037 2.2220179 0.006203610 0.114458670 0.35642113 7 87570172 87570223 52 - 0.392 0.617 1.098
ENSG00000085563 E038 2.9214545 0.024976135 0.925273119 0.97746857 7 87585512 87585653 142 - 0.595 0.586 -0.039
ENSG00000085563 E039 0.7244581 0.014169594 0.648434123 0.85157363 7 87585654 87585680 27 - 0.265 0.196 -0.554
ENSG00000085563 E040 1.8144261 0.008246402 0.472865228 0.74004243 7 87595766 87595814 49 - 0.491 0.385 -0.554
ENSG00000085563 E041 1.4508300 0.009085852 0.520138580 0.77461058 7 87600117 87600190 74 - 0.428 0.331 -0.554
ENSG00000085563 E042 0.7258985 0.021461933 0.651104337 0.85302431 7 87600755 87600812 58 - 0.265 0.196 -0.554
ENSG00000085563 E043 0.7258985 0.021461933 0.651104337 0.85302431 7 87600813 87600825 13 - 0.265 0.196 -0.554
ENSG00000085563 E044 0.7258985 0.021461933 0.651104337 0.85302431 7 87600826 87600972 147 - 0.265 0.196 -0.554
ENSG00000085563 E045 0.0000000       7 87600973 87601078 106 -      
ENSG00000085563 E046 0.0000000       7 87602960 87603140 181 -      
ENSG00000085563 E047 0.0000000       7 87713161 87713323 163 -      

Help

Please Click HERE to learn more details about the results from DEXseq.