ENSG00000085662

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000285930 ENSG00000085662 No_inf pgKDN_inf AKR1B1 protein_coding protein_coding 49.84057 51.01145 50.51758 2.250722 1.205833 -0.01403272 42.849775 42.70039 44.430660 1.686083 1.559352 0.05729333 0.86005 0.837625 0.879625 0.04200 0.64500265 0.03497284 FALSE  
ENST00000489022 ENSG00000085662 No_inf pgKDN_inf AKR1B1 protein_coding protein_coding_CDS_not_defined 49.84057 51.01145 50.51758 2.250722 1.205833 -0.01403272 1.206239 0.00000 2.594082 0.000000 1.040230 8.02463089 0.02455 0.000000 0.050050 0.05005 0.03497284 0.03497284 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000085662 E001 3.8421367 0.1272691413 0.3423842347 0.63381333 7 134442356 134442385 30 - 0.561 0.761 0.855
ENSG00000085662 E002 3.9608398 0.1316008872 0.4371646950 0.71352842 7 134442386 134442386 1 - 0.591 0.761 0.718
ENSG00000085662 E003 92.2195563 0.0024828501 0.9832865469 0.99869026 7 134442387 134442770 384 - 1.964 1.970 0.020
ENSG00000085662 E004 0.3809057 0.0158721284 0.1376834420   7 134444727 134445237 511 - 0.000 0.226 11.545
ENSG00000085662 E005 42.9633542 0.0019884579 0.2744217212 0.56796735 7 134445238 134445320 83 - 1.608 1.665 0.193
ENSG00000085662 E006 37.7595682 0.0010545909 0.0224667690 0.13628644 7 134447298 134447381 84 - 1.517 1.634 0.398
ENSG00000085662 E007 1.6120211 0.0086773839 0.2680009658 0.56146898 7 134447382 134447460 79 - 0.313 0.484 0.955
ENSG00000085662 E008 6.4915699 0.0021995976 0.0006638972 0.01088348 7 134447461 134447849 389 - 0.620 1.004 1.522
ENSG00000085662 E009 1.6427370 0.0230558772 0.0031229971 0.03555011 7 134447850 134447955 106 - 0.102 0.571 3.370
ENSG00000085662 E010 1.0080587 0.0119352737 0.0445504725 0.20633909 7 134447956 134447979 24 - 0.102 0.413 2.592
ENSG00000085662 E011 38.5798000 0.0038698259 0.8777115223 0.95849528 7 134447980 134448061 82 - 1.588 1.600 0.043
ENSG00000085662 E012 43.5644331 0.0109887198 0.6684363553 0.86194358 7 134448387 134448493 107 - 1.656 1.638 -0.060
ENSG00000085662 E013 32.7467656 0.0004211074 0.5190408997 0.77380523 7 134448997 134449054 58 - 1.541 1.513 -0.096
ENSG00000085662 E014 20.8503639 0.0006771801 0.5584420245 0.80010127 7 134449055 134449057 3 - 1.355 1.322 -0.113
ENSG00000085662 E015 31.5938036 0.0005844885 0.1533902625 0.41799467 7 134449058 134449095 38 - 1.548 1.478 -0.237
ENSG00000085662 E016 24.4151150 0.0005822914 0.0151155007 0.10568310 7 134449096 134449119 24 - 1.473 1.336 -0.475
ENSG00000085662 E017 0.3721553 0.2501514644 0.7358863861   7 134449120 134449135 16 - 0.102 0.163 0.786
ENSG00000085662 E018 0.3731628 0.2620155260 0.7440673903   7 134449136 134449577 442 - 0.102 0.163 0.785
ENSG00000085662 E019 0.8809224 0.0135696877 0.0779802661 0.28566105 7 134449578 134449684 107 - 0.102 0.374 2.370
ENSG00000085662 E020 0.7615290 0.0132769282 0.0157312828 0.10855490 7 134449685 134449718 34 - 0.000 0.373 12.476
ENSG00000085662 E021 0.5078857 0.0161024081 0.0647849718 0.25656196 7 134449719 134449719 1 - 0.000 0.281 11.930
ENSG00000085662 E022 35.7712212 0.0004163458 0.2017289078 0.48408978 7 134449720 134449797 78 - 1.594 1.537 -0.195
ENSG00000085662 E023 37.0290856 0.0003745364 0.4741466390 0.74091939 7 134450786 134450902 117 - 1.594 1.564 -0.100
ENSG00000085662 E024 0.4987885 0.0260904845 0.4061504480   7 134450903 134450957 55 - 0.102 0.226 1.370
ENSG00000085662 E025 1.6335138 0.0177977899 0.0221931364 0.13544920 7 134451294 134451585 292 - 0.184 0.544 2.244
ENSG00000085662 E026 33.6122353 0.0004453364 0.0423519047 0.20050980 7 134451586 134451753 168 - 1.588 1.491 -0.330
ENSG00000085662 E027 0.1265070 0.0123084906 0.6304943761   7 134451754 134451806 53 - 0.000 0.089 10.042
ENSG00000085662 E028 15.2446520 0.0034857363 0.7269125360 0.89082710 7 134458997 134459121 125 - 1.190 1.222 0.112
ENSG00000085662 E029 1.8140142 0.0081868419 0.1113938832 0.35051459 7 134459122 134459284 163 - 0.561 0.330 -1.215

Help

Please Click HERE to learn more details about the results from DEXseq.