ENSG00000086589

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000199814 ENSG00000086589 No_inf pgKDN_inf RBM22 protein_coding protein_coding 38.6282 37.11855 40.01887 0.6893371 1.704662 0.1085118 29.333374 24.026050 33.917717 1.4610491 1.1172313 0.4972646 0.75828333 0.648325 0.849475 0.201150 0.0175241 0.0175241 FALSE TRUE
ENST00000520132 ENSG00000086589 No_inf pgKDN_inf RBM22 protein_coding retained_intron 38.6282 37.11855 40.01887 0.6893371 1.704662 0.1085118 4.300350 5.513794 3.335199 0.8203671 0.7827499 -0.7235672 0.11263333 0.148800 0.084175 -0.064625 0.5839425 0.0175241 FALSE FALSE
ENST00000522469 ENSG00000086589 No_inf pgKDN_inf RBM22 protein_coding retained_intron 38.6282 37.11855 40.01887 0.6893371 1.704662 0.1085118 2.387152 4.203711 1.104504 0.5841863 0.6885263 -1.9186900 0.06235833 0.112950 0.026450 -0.086500 0.2317909 0.0175241 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000086589 E001 0.8535118 0.0716398226 0.733576655 0.89414863 5 150690792 150690793 2 - 0.295 0.241 -0.393
ENSG00000086589 E002 168.6467411 0.0006588363 0.257347002 0.54956539 5 150690794 150691518 725 - 2.216 2.242 0.086
ENSG00000086589 E003 63.2166877 0.0097645603 0.790449543 0.91966838 5 150691519 150691881 363 - 1.799 1.816 0.056
ENSG00000086589 E004 33.1715795 0.0022126413 0.932077155 0.98022130 5 150692895 150693026 132 - 1.535 1.532 -0.009
ENSG00000086589 E005 36.9616263 0.0004763397 0.897391790 0.96613081 5 150693219 150693307 89 - 1.582 1.577 -0.016
ENSG00000086589 E006 32.6258210 0.0065507735 0.033444325 0.17396369 5 150694076 150694240 165 - 1.587 1.461 -0.433
ENSG00000086589 E007 12.6287269 0.0241488915 0.009300557 0.07674182 5 150694241 150694740 500 - 0.978 1.244 0.960
ENSG00000086589 E008 10.5043778 0.0020466560 0.020571614 0.12919299 5 150694741 150695180 440 - 0.943 1.148 0.750
ENSG00000086589 E009 5.5973048 0.0025836054 0.003853408 0.04137931 5 150695324 150695505 182 - 0.619 0.949 1.322
ENSG00000086589 E010 13.6637596 0.0093727409 0.344342992 0.63565030 5 150695506 150695546 41 - 1.206 1.125 -0.288
ENSG00000086589 E011 29.3011157 0.0039637847 0.689821947 0.87258057 5 150695547 150695693 147 - 1.469 1.493 0.083
ENSG00000086589 E012 11.0065720 0.0012783956 0.716020744 0.88550739 5 150695694 150695706 13 - 1.094 1.065 -0.106
ENSG00000086589 E013 23.2036456 0.0005874077 0.346460079 0.63719224 5 150696533 150696594 62 - 1.411 1.356 -0.190
ENSG00000086589 E014 25.9807645 0.0032034420 0.198132115 0.47953468 5 150696595 150696666 72 - 1.469 1.392 -0.263
ENSG00000086589 E015 17.5836154 0.0009240519 0.445120714 0.71954506 5 150696667 150696705 39 - 1.294 1.244 -0.178
ENSG00000086589 E016 0.3723465 0.0167200060 0.576202079   5 150696706 150696790 85 - 0.094 0.174 1.022
ENSG00000086589 E017 23.3242337 0.0005798236 0.311484029 0.60464443 5 150696791 150696891 101 - 1.415 1.356 -0.205
ENSG00000086589 E018 25.1957209 0.0019514692 0.643097310 0.84869546 5 150698499 150698631 133 - 1.431 1.405 -0.090
ENSG00000086589 E019 9.9451750 0.0273201176 0.641881132 0.84807371 5 150699242 150699255 14 - 1.010 1.065 0.201
ENSG00000086589 E020 8.6208421 0.0263001178 0.320196566 0.61302338 5 150699256 150699271 16 - 0.918 1.036 0.438
ENSG00000086589 E021 8.4756707 0.0210444053 0.598895724 0.82404311 5 150700444 150700476 33 - 0.943 1.006 0.232
ENSG00000086589 E022 7.6961406 0.0018155469 0.561897769 0.80202705 5 150700477 150700497 21 - 0.966 0.911 -0.207
ENSG00000086589 E023 0.4989795 0.0342359301 0.317859579   5 150700498 150700910 413 - 0.094 0.241 1.607
ENSG00000086589 E024 12.2632724 0.0063386641 0.021433211 0.13255118 5 150700932 150701093 162 - 1.212 1.016 -0.707

Help

Please Click HERE to learn more details about the results from DEXseq.