ENSG00000086666

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261749 ENSG00000086666 No_inf pgKDN_inf ZFAND6 protein_coding protein_coding 58.28523 50.69465 72.03508 1.450515 2.345646 0.5067817 8.020706 6.773134 9.010219 1.260465 3.159393 0.4112106 0.13957500 0.133050 0.127000 -0.00605 0.9140105169653 0.0000001451782 FALSE TRUE
ENST00000558494 ENSG00000086666 No_inf pgKDN_inf ZFAND6 protein_coding protein_coding 58.28523 50.69465 72.03508 1.450515 2.345646 0.5067817 7.733711 11.141945 4.489991 4.662246 4.489991 -1.3093013 0.14075000 0.214400 0.059600 -0.15480 0.3762060351806 0.0000001451782 FALSE TRUE
ENST00000561060 ENSG00000086666 No_inf pgKDN_inf ZFAND6 protein_coding protein_coding 58.28523 50.69465 72.03508 1.450515 2.345646 0.5067817 31.605801 28.290578 37.981627 4.733341 8.754992 0.4248500 0.54693333 0.565325 0.530725 -0.03460 0.9606007711738 0.0000001451782 FALSE TRUE
MSTRG.10050.8 ENSG00000086666 No_inf pgKDN_inf ZFAND6 protein_coding   58.28523 50.69465 72.03508 1.450515 2.345646 0.5067817 3.413749 0.000000 7.965875 0.000000 2.048484 9.6394989 0.05064167 0.000000 0.108250 0.10825 0.0000001451782 0.0000001451782 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000086666 E001 0.0000000       15 80059568 80059612 45 +      
ENSG00000086666 E002 0.0000000       15 80059613 80059634 22 +      
ENSG00000086666 E003 0.0000000       15 80059635 80059675 41 +      
ENSG00000086666 E004 2.0584989 0.00711177715 0.45969034627 0.73133356 15 80059676 80059689 14 + 0.531 0.423 -0.538
ENSG00000086666 E005 10.0292172 0.00148683522 0.41031868256 0.69215280 15 80059690 80059713 24 + 1.006 1.079 0.266
ENSG00000086666 E006 25.4981962 0.00056338283 0.82637869491 0.93713640 15 80059714 80059809 96 + 1.416 1.429 0.045
ENSG00000086666 E007 0.7250472 0.77417054051 0.95940764025 0.99041933 15 80059931 80059936 6 + 0.272 0.190 -0.661
ENSG00000086666 E008 1.9231194 0.09180736284 0.18488603395 0.46237797 15 80059937 80059963 27 + 0.558 0.322 -1.248
ENSG00000086666 E009 0.2459655 0.01645506092 0.85743365057   15 80060160 80060247 88 + 0.086 0.106 0.336
ENSG00000086666 E010 1.1966513 0.01026803901 0.11094713611 0.34965312 15 80060424 80060740 317 + 0.438 0.190 -1.664
ENSG00000086666 E011 0.0000000       15 80072564 80072577 14 +      
ENSG00000086666 E012 0.0000000       15 80072578 80072582 5 +      
ENSG00000086666 E013 0.0000000       15 80072583 80072586 4 +      
ENSG00000086666 E014 0.0000000       15 80072587 80072587 1 +      
ENSG00000086666 E015 0.0000000       15 80072588 80072589 2 +      
ENSG00000086666 E016 0.0000000       15 80072590 80072590 1 +      
ENSG00000086666 E017 0.3542802 0.03401361243 0.15899218525   15 80072591 80072607 17 + 0.218 0.000 -11.556
ENSG00000086666 E018 0.9531101 0.01204746745 0.05538629877 0.23445924 15 80072608 80072647 40 + 0.402 0.106 -2.471
ENSG00000086666 E019 0.6070457 0.01994758174 0.84916637250 0.94642935 15 80073266 80073330 65 + 0.218 0.190 -0.249
ENSG00000086666 E020 0.0000000       15 80075161 80075163 3 +      
ENSG00000086666 E021 0.3716209 0.01665065139 0.44990918876   15 80075164 80075190 27 + 0.086 0.190 1.336
ENSG00000086666 E022 0.4984749 0.02503819414 0.22290625474   15 80075191 80075242 52 + 0.086 0.261 1.921
ENSG00000086666 E023 0.0000000       15 80075243 80075315 73 +      
ENSG00000086666 E024 10.4202142 0.00145799044 0.12513737527 0.37497412 15 80098416 80098578 163 + 1.113 0.979 -0.491
ENSG00000086666 E025 0.0000000       15 80111428 80111559 132 +      
ENSG00000086666 E026 0.0000000       15 80112776 80112854 79 +      
ENSG00000086666 E027 0.2447669 0.01645902158 0.85671878411   15 80115027 80115070 44 + 0.086 0.106 0.336
ENSG00000086666 E028 58.5843024 0.00026442281 0.00059779283 0.01004248 15 80120328 80120498 171 + 1.829 1.699 -0.441
ENSG00000086666 E029 0.0000000       15 80120499 80120802 304 +      
ENSG00000086666 E030 22.5165725 0.00065252500 0.00604983638 0.05685518 15 80121712 80121718 7 + 1.441 1.270 -0.595
ENSG00000086666 E031 29.7378816 0.00047106706 0.04364654596 0.20397130 15 80121719 80121747 29 + 1.533 1.424 -0.373
ENSG00000086666 E032 38.8319897 0.00038252025 0.02367252025 0.14072230 15 80121748 80121820 73 + 1.645 1.538 -0.363
ENSG00000086666 E033 42.9273352 0.00035560539 0.21966635813 0.50624298 15 80122700 80122800 101 + 1.666 1.611 -0.184
ENSG00000086666 E034 1.0903489 0.01121872416 0.50896051848 0.76703526 15 80122801 80123067 267 + 0.363 0.261 -0.664
ENSG00000086666 E035 13.9593932 0.01413354476 0.00114251421 0.01659584 15 80129600 80131179 1580 + 1.016 1.306 1.039
ENSG00000086666 E036 44.4748496 0.00033354006 0.00803460052 0.06932301 15 80131180 80131293 114 + 1.600 1.715 0.392
ENSG00000086666 E037 0.1176306 0.01174585506 0.67654512251   15 80131294 80131517 224 + 0.086 0.000 -10.209
ENSG00000086666 E038 239.8498905 0.00009697668 0.00004551166 0.00123348 15 80137480 80138393 914 + 2.351 2.412 0.204

Help

Please Click HERE to learn more details about the results from DEXseq.