ENSG00000087077

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000200457 ENSG00000087077 No_inf pgKDN_inf TRIP6 protein_coding protein_coding 51.52508 39.95503 56.20252 2.34897 2.099472 0.4921531 33.912773 19.067108 43.083222 2.9115217 2.3368510 1.1756185 0.64067500 0.474300 0.765225 0.290925 0.001411695 0.001411695 FALSE TRUE
ENST00000488670 ENSG00000087077 No_inf pgKDN_inf TRIP6 protein_coding retained_intron 51.52508 39.95503 56.20252 2.34897 2.099472 0.4921531 5.888041 6.095587 5.067212 0.8565753 1.3316575 -0.2660936 0.11640833 0.151750 0.088050 -0.063700 0.584773718 0.001411695   FALSE
ENST00000619988 ENSG00000087077 No_inf pgKDN_inf TRIP6 protein_coding protein_coding 51.52508 39.95503 56.20252 2.34897 2.099472 0.4921531 3.854044 4.720207 1.880689 3.1660103 1.8806893 -1.3229911 0.08033333 0.121125 0.037525 -0.083600 0.779242291 0.001411695 FALSE TRUE
MSTRG.26610.1 ENSG00000087077 No_inf pgKDN_inf TRIP6 protein_coding   51.52508 39.95503 56.20252 2.34897 2.099472 0.4921531 2.648933 3.312739 1.773093 0.9187482 0.1388322 -0.8979908 0.05649167 0.088525 0.031950 -0.056575 0.467842643 0.001411695 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000087077 E001 1.1078142 0.2224102805 0.5875237097 0.816974634 7 100867288 100867386 99 + 0.264 0.386 0.776
ENSG00000087077 E002 0.9805518 0.1063210007 0.6919295121 0.873888308 7 100867387 100867388 2 + 0.264 0.332 0.453
ENSG00000087077 E003 1.2250364 0.0719076700 0.6432087729 0.848695462 7 100867389 100867393 5 + 0.311 0.386 0.453
ENSG00000087077 E004 13.8450595 0.0046611533 0.5942899669 0.821520276 7 100867394 100867497 104 + 1.188 1.143 -0.164
ENSG00000087077 E005 22.9813157 0.0235270806 0.0557965495 0.235382391 7 100867498 100867606 109 + 1.440 1.280 -0.559
ENSG00000087077 E006 4.1089294 0.0064048927 0.0004602215 0.008194648 7 100867607 100867860 254 + 0.460 0.896 1.868
ENSG00000087077 E007 16.3081837 0.0008589393 0.0148984728 0.104640478 7 100867861 100867910 50 + 1.306 1.124 -0.644
ENSG00000087077 E008 21.2232175 0.0007707957 0.1406148362 0.398921110 7 100867911 100867988 78 + 1.384 1.286 -0.341
ENSG00000087077 E009 1.6051561 0.0632229756 0.2067881701 0.490431958 7 100867989 100868035 47 + 0.311 0.517 1.131
ENSG00000087077 E010 1.8578530 0.0514073747 0.0783410071 0.286554349 7 100868036 100868107 72 + 0.311 0.587 1.453
ENSG00000087077 E011 28.8586521 0.0191371073 0.1865503547 0.464534682 7 100868108 100868233 126 + 1.516 1.409 -0.368
ENSG00000087077 E012 2.3556141 0.0378683705 0.0331447398 0.173018621 7 100868296 100868494 199 + 0.353 0.674 1.568
ENSG00000087077 E013 58.2332174 0.0002991292 0.3201544605 0.612964525 7 100868495 100868810 316 + 1.787 1.746 -0.139
ENSG00000087077 E014 19.2591882 0.0007743761 0.6673444757 0.861529885 7 100868811 100868866 56 + 1.293 1.317 0.086
ENSG00000087077 E015 22.1787878 0.0006306113 0.6964438064 0.876053422 7 100870370 100870463 94 + 1.353 1.373 0.070
ENSG00000087077 E016 0.4912665 0.1170374701 0.7548676297   7 100870464 100870573 110 + 0.152 0.197 0.453
ENSG00000087077 E017 54.1017110 0.0002566521 0.4255182904 0.704552409 7 100870574 100870743 170 + 1.753 1.718 -0.118
ENSG00000087077 E018 5.6597973 0.0025548521 0.0493962871 0.219179717 7 100870783 100871008 226 + 0.715 0.927 0.832
ENSG00000087077 E019 2.4751909 0.0057687477 0.0407115034 0.195768030 7 100871061 100871177 117 + 0.392 0.674 1.346
ENSG00000087077 E020 68.7586565 0.0002406076 0.0319038728 0.168812271 7 100871543 100871721 179 + 1.809 1.878 0.232
ENSG00000087077 E021 48.3912746 0.0003668778 0.4413012368 0.716820744 7 100872624 100872744 121 + 1.678 1.706 0.095
ENSG00000087077 E022 2.4382434 0.0056121117 0.7878677281 0.918663609 7 100872745 100872833 89 + 0.519 0.554 0.164
ENSG00000087077 E023 58.4552802 0.0018950757 0.8220462119 0.935462399 7 100873172 100873454 283 + 1.769 1.774 0.017

Help

Please Click HERE to learn more details about the results from DEXseq.