ENSG00000087087

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000448764 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding protein_coding 71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 12.004167 13.182517 10.3595487 2.0687933 3.1561284 -0.3473667 0.16927500 0.177775 0.164550 -0.013225 0.90684893 0.01049626 FALSE  
ENST00000460194 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding retained_intron 71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 5.482851 8.489825 2.6570172 2.8045728 1.2507821 -1.6722059 0.07333333 0.110625 0.042600 -0.068025 0.52808883 0.01049626 FALSE  
ENST00000466432 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding retained_intron 71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 2.456322 5.257564 0.2800266 1.1309594 0.2800266 -4.1828789 0.03320833 0.071150 0.004450 -0.066700 0.01049626 0.01049626    
ENST00000469602 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding retained_intron 71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 1.423852 4.271556 0.0000000 2.7249456 0.0000000 -8.7419913 0.01854167 0.055625 0.000000 -0.055625 0.51844523 0.01049626    
ENST00000611405 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding protein_coding 71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 7.780820 1.479865 9.3225521 1.4798652 5.4126690 2.6470899 0.10987500 0.018450 0.148050 0.129600 0.83443380 0.01049626 FALSE  
ENST00000614484 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding protein_coding 71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 9.205190 7.847673 6.5852267 5.2479776 4.0001248 -0.2526799 0.13268333 0.111000 0.104550 -0.006450 1.00000000 0.01049626 FALSE  
ENST00000618262 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding protein_coding 71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 4.427653 4.789039 8.4939197 2.7652399 5.2609029 0.8253825 0.06531667 0.061000 0.134950 0.073950 1.00000000 0.01049626 FALSE  
ENST00000618411 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding protein_coding 71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 6.868121 2.763454 8.8894357 1.5971297 5.1509896 1.6820302 0.09909167 0.037500 0.141125 0.103625 0.97777087 0.01049626 FALSE  
MSTRG.26627.10 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding   71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 3.931328 4.497003 2.5142064 1.3804681 0.9114134 -0.8363386 0.05554167 0.061725 0.040025 -0.021700 0.83537059 0.01049626 FALSE  
MSTRG.26627.6 ENSG00000087087 No_inf pgKDN_inf SRRT protein_coding   71.00293 74.60038 63.01874 2.365752 0.4807704 -0.2433666 3.722863 5.895718 1.8353471 0.5852292 0.3702798 -1.6782202 0.05142500 0.079475 0.029000 -0.050475 0.16921939 0.01049626 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000087087 E001 0.5002381 0.0332640354 3.758070e-01 6.631292e-01 7 100874983 100875102 120 + 0.099 0.230 1.444
ENSG00000087087 E002 0.3815350 0.0344228371 1.272688e-01   7 100875103 100875110 8 + 0.000 0.230 12.085
ENSG00000087087 E003 0.6167962 0.2215378428 7.544831e-01 9.033947e-01 7 100875111 100875116 6 + 0.180 0.230 0.445
ENSG00000087087 E004 0.9802013 0.3103175891 9.184169e-01 9.743996e-01 7 100875117 100875125 9 + 0.307 0.286 -0.140
ENSG00000087087 E005 1.4606103 0.2834325940 5.422627e-01 7.896109e-01 7 100875126 100875131 6 + 0.447 0.336 -0.625
ENSG00000087087 E006 3.5532276 0.1211800315 9.728323e-01 9.949139e-01 7 100875132 100875162 31 + 0.662 0.653 -0.040
ENSG00000087087 E007 6.7312303 0.0038349860 6.128150e-01 8.316964e-01 7 100875163 100875184 22 + 0.914 0.863 -0.193
ENSG00000087087 E008 20.7824931 0.0048663109 1.210895e-03 1.733699e-02 7 100875185 100875328 144 + 1.443 1.221 -0.775
ENSG00000087087 E009 0.1272623 0.0123509553 5.959850e-01   7 100875390 100875453 64 + 0.000 0.091 10.500
ENSG00000087087 E010 26.8999426 0.0020295182 1.295413e-01 3.818065e-01 7 100875573 100875712 140 + 1.489 1.402 -0.298
ENSG00000087087 E011 0.5907441 0.0400265770 1.675750e-02 1.128763e-01 7 100875713 100875936 224 + 0.359 0.000 -13.209
ENSG00000087087 E012 2.7002250 0.0082463172 8.563622e-01 9.495498e-01 7 100880696 100880769 74 + 0.553 0.580 0.123
ENSG00000087087 E013 34.9150283 0.0129565842 9.115802e-02 3.135934e-01 7 100881285 100881413 129 + 1.611 1.499 -0.383
ENSG00000087087 E014 8.7331709 0.0020196852 8.303668e-05 2.036608e-03 7 100881414 100881658 245 + 0.730 1.126 1.500
ENSG00000087087 E015 25.1372362 0.0005867277 4.689929e-02 2.127310e-01 7 100881659 100881763 105 + 1.474 1.360 -0.393
ENSG00000087087 E016 15.0540253 0.0010130198 5.105488e-01 7.680560e-01 7 100881764 100881805 42 + 1.229 1.182 -0.164
ENSG00000087087 E017 41.7872324 0.0031958461 8.050273e-04 1.266579e-02 7 100882053 100882241 189 + 1.713 1.545 -0.573
ENSG00000087087 E018 15.7137779 0.0012359723 1.903658e-07 1.044475e-05 7 100882242 100882457 216 + 0.953 1.365 1.475
ENSG00000087087 E019 19.4867553 0.0500318633 1.281419e-04 2.900213e-03 7 100882458 100882719 262 + 0.988 1.469 1.702
ENSG00000087087 E020 4.9790596 0.0048068339 1.164427e-02 8.884168e-02 7 100882720 100882764 45 + 0.583 0.890 1.258
ENSG00000087087 E021 19.3622395 0.0017067978 1.410609e-04 3.145093e-03 7 100882765 100883090 326 + 1.141 1.410 0.944
ENSG00000087087 E022 47.1941565 0.0003718145 4.010138e-11 4.224273e-09 7 100883091 100884069 979 + 1.492 1.795 1.028
ENSG00000087087 E023 36.2967263 0.0003982695 4.609607e-02 2.105832e-01 7 100884070 100884239 170 + 1.619 1.524 -0.325
ENSG00000087087 E024 47.3022136 0.0003321243 5.695486e-01 8.064381e-01 7 100884368 100884552 185 + 1.667 1.695 0.092
ENSG00000087087 E025 24.7696029 0.0005518719 7.554264e-01 9.035894e-01 7 100884740 100884753 14 + 1.418 1.402 -0.055
ENSG00000087087 E026 48.1555310 0.0002919141 4.369343e-01 7.133529e-01 7 100884754 100884838 85 + 1.706 1.676 -0.104
ENSG00000087087 E027 44.5421659 0.0003245232 9.897695e-01 1.000000e+00 7 100884923 100884991 69 + 1.655 1.658 0.011
ENSG00000087087 E028 37.9073105 0.0003801852 1.079836e-01 3.445738e-01 7 100884992 100885040 49 + 1.543 1.624 0.275
ENSG00000087087 E029 11.0670905 0.0100269452 4.783582e-01 7.443458e-01 7 100885213 100885215 3 + 1.042 1.110 0.247
ENSG00000087087 E030 42.5533358 0.0003866054 9.604742e-01 9.911075e-01 7 100885216 100885294 79 + 1.637 1.638 0.001
ENSG00000087087 E031 45.9918757 0.0003198003 9.016023e-01 9.683571e-01 7 100885295 100885370 76 + 1.672 1.669 -0.010
ENSG00000087087 E032 2.4945469 0.0095634889 4.347441e-02 2.033960e-01 7 100885371 100885587 217 + 0.359 0.653 1.445
ENSG00000087087 E033 22.3123603 0.0006777759 7.930095e-02 2.887535e-01 7 100885701 100885707 7 + 1.301 1.414 0.392
ENSG00000087087 E034 32.4045305 0.0004305584 6.893767e-02 2.652854e-01 7 100885708 100885762 55 + 1.466 1.564 0.336
ENSG00000087087 E035 0.3703650 0.0165841218 6.496655e-01   7 100885763 100885774 12 + 0.099 0.166 0.860
ENSG00000087087 E036 39.3010301 0.0003642729 2.734706e-01 5.672177e-01 7 100885863 100885941 79 + 1.630 1.581 -0.167
ENSG00000087087 E037 3.1443297 0.0046331537 1.742913e-04 3.737665e-03 7 100885942 100886246 305 + 0.248 0.787 2.734
ENSG00000087087 E038 72.8027507 0.0002272259 4.722940e-02 2.134823e-01 7 100886247 100886435 189 + 1.901 1.835 -0.223
ENSG00000087087 E039 1.5154714 0.0091317727 3.505845e-03 3.882634e-02 7 100886560 100886794 235 + 0.099 0.552 3.319
ENSG00000087087 E040 68.0922123 0.0024696215 9.277518e-01 9.785977e-01 7 100886795 100886968 174 + 1.835 1.841 0.021
ENSG00000087087 E041 0.6348346 0.1573988313 4.477604e-02 2.069190e-01 7 100887002 100887046 45 + 0.000 0.336 12.822
ENSG00000087087 E042 63.2825464 0.0002443644 9.055257e-03 7.537988e-02 7 100887047 100887200 154 + 1.855 1.761 -0.319
ENSG00000087087 E043 33.3286250 0.0004081186 5.416852e-01 7.892699e-01 7 100887320 100887347 28 + 1.549 1.521 -0.098
ENSG00000087087 E044 83.3730665 0.0002035215 6.631404e-01 8.596827e-01 7 100887348 100887513 166 + 1.931 1.919 -0.039
ENSG00000087087 E045 3.0291255 0.0287661652 9.568946e-05 2.289670e-03 7 100887514 100887702 189 + 0.180 0.787 3.319
ENSG00000087087 E046 80.3611370 0.0005099239 3.080038e-01 6.012775e-01 7 100887703 100887859 157 + 1.888 1.925 0.125
ENSG00000087087 E047 1.6156363 0.0082129616 2.275671e-01 5.160011e-01 7 100887860 100887934 75 + 0.307 0.491 1.029
ENSG00000087087 E048 0.6344876 0.0150928496 2.724061e-02 1.534728e-01 7 100888035 100888041 7 + 0.000 0.336 12.822
ENSG00000087087 E049 12.5679949 0.0050401615 2.321724e-01 5.208252e-01 7 100888042 100888053 12 + 1.072 1.176 0.374
ENSG00000087087 E050 39.6129943 0.0035386317 1.028121e-01 3.352060e-01 7 100888054 100888143 90 + 1.650 1.567 -0.283
ENSG00000087087 E051 2.7045653 0.0116852358 8.571883e-01 9.499578e-01 7 100888144 100888256 113 + 0.553 0.580 0.122
ENSG00000087087 E052 24.8032054 0.0011369925 7.889784e-02 2.879169e-01 7 100888257 100888277 21 + 1.463 1.360 -0.354
ENSG00000087087 E053 40.2354322 0.0004447873 7.838567e-04 1.242331e-02 7 100888278 100888383 106 + 1.691 1.536 -0.528
ENSG00000087087 E054 3.0662219 0.0047858196 9.537445e-01 9.885891e-01 7 100888384 100888473 90 + 0.611 0.605 -0.025
ENSG00000087087 E055 33.1202592 0.0038856875 1.112198e-01 3.501626e-01 7 100888474 100888664 191 + 1.577 1.489 -0.300

Help

Please Click HERE to learn more details about the results from DEXseq.