ENSG00000087365

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000322535 ENSG00000087365 No_inf pgKDN_inf SF3B2 protein_coding protein_coding 90.47143 76.01678 94.64583 2.483577 1.115578 0.3161836 65.131948 49.8766692 75.631563 2.8559186 2.503178 0.6005248 0.71862500 0.657725 0.799575 0.14185 0.10924041 0.03343493 FALSE  
ENST00000528302 ENSG00000087365 No_inf pgKDN_inf SF3B2 protein_coding protein_coding 90.47143 76.01678 94.64583 2.483577 1.115578 0.3161836 5.137034 0.7170171 9.386926 0.4141627 3.149146 3.6921277 0.05306667 0.009700 0.098550 0.08885 0.03343493 0.03343493 FALSE  
ENST00000529994 ENSG00000087365 No_inf pgKDN_inf SF3B2 protein_coding retained_intron 90.47143 76.01678 94.64583 2.483577 1.115578 0.3161836 8.517749 10.1790614 2.557417 0.8096397 1.545080 -1.9886316 0.09520000 0.134750 0.026450 -0.10830 0.12655812 0.03343493 FALSE  
MSTRG.4977.5 ENSG00000087365 No_inf pgKDN_inf SF3B2 protein_coding   90.47143 76.01678 94.64583 2.483577 1.115578 0.3161836 4.211179 5.7607120 1.574254 1.4950167 1.083000 -1.8649455 0.04811667 0.075675 0.016825 -0.05885 0.22324450 0.03343493 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000087365 E001 0.0000000       11 66050729 66050823 95 +      
ENSG00000087365 E002 0.0000000       11 66050826 66051011 186 +      
ENSG00000087365 E003 0.1187032 0.0118563175 6.667261e-01   11 66051520 66051603 84 + 0.086 0.000 -10.929
ENSG00000087365 E004 0.0000000       11 66051893 66052035 143 +      
ENSG00000087365 E005 0.0000000       11 66052036 66052330 295 +      
ENSG00000087365 E006 0.7261573 0.0138766460 5.778326e-01 8.113432e-01 11 66052331 66052363 33 + 0.274 0.189 -0.687
ENSG00000087365 E007 1.1066546 0.0106560792 5.147085e-01 7.711405e-01 11 66052364 66052364 1 + 0.274 0.374 0.635
ENSG00000087365 E008 1.1066546 0.0106560792 5.147085e-01 7.711405e-01 11 66052365 66052365 1 + 0.274 0.374 0.635
ENSG00000087365 E009 8.5556789 0.0148448582 6.944173e-01 8.752268e-01 11 66052366 66052392 27 + 0.960 1.000 0.148
ENSG00000087365 E010 9.5357890 0.0133987540 6.441720e-01 8.492705e-01 11 66052393 66052399 7 + 1.000 1.045 0.165
ENSG00000087365 E011 22.4607101 0.0008296464 7.779933e-01 9.148664e-01 11 66052400 66052517 118 + 1.361 1.379 0.061
ENSG00000087365 E012 0.2357071 0.0156804871 3.257942e-01   11 66052596 66052672 77 + 0.158 0.000 -11.928
ENSG00000087365 E013 9.4338615 0.0213580640 3.628511e-01 6.519203e-01 11 66052673 66052687 15 + 0.971 1.066 0.350
ENSG00000087365 E014 14.4975213 0.0264832394 9.372174e-01 9.820871e-01 11 66052688 66052719 32 + 1.196 1.181 -0.052
ENSG00000087365 E015 0.2533610 0.0160671105 1.767659e-01   11 66052720 66053026 307 + 0.000 0.189 12.449
ENSG00000087365 E016 28.2756039 0.0107736538 1.247823e-01 3.744510e-01 11 66053027 66053104 78 + 1.513 1.403 -0.381
ENSG00000087365 E017 2.2546569 0.0092085620 8.495728e-04 1.322773e-02 11 66053105 66053960 856 + 0.220 0.707 2.635
ENSG00000087365 E018 55.7378758 0.0002748614 1.162174e-02 8.875142e-02 11 66055076 66055292 217 + 1.797 1.695 -0.346
ENSG00000087365 E019 27.3560665 0.0005787609 6.818954e-01 8.683117e-01 11 66055293 66055315 23 + 1.440 1.464 0.081
ENSG00000087365 E020 0.0000000       11 66055316 66055320 5 +      
ENSG00000087365 E021 0.2543986 0.0159933211 1.769673e-01   11 66055321 66055441 121 + 0.000 0.189 12.449
ENSG00000087365 E022 18.5396826 0.0008082659 8.968058e-01 9.659631e-01 11 66055535 66055537 3 + 1.294 1.285 -0.030
ENSG00000087365 E023 33.7195872 0.0049432201 6.758106e-01 8.657760e-01 11 66055538 66055585 48 + 1.528 1.552 0.082
ENSG00000087365 E024 1.5905531 0.0294812404 9.143583e-01 9.730855e-01 11 66055586 66055840 255 + 0.404 0.421 0.090
ENSG00000087365 E025 52.7769353 0.0003047216 5.527573e-01 7.961441e-01 11 66056838 66056955 118 + 1.741 1.716 -0.083
ENSG00000087365 E026 18.1985814 0.0008864328 6.801195e-01 8.678945e-01 11 66057266 66057268 3 + 1.269 1.297 0.099
ENSG00000087365 E027 20.3999232 0.0006779961 5.889574e-01 8.177524e-01 11 66057269 66057269 1 + 1.313 1.348 0.123
ENSG00000087365 E028 44.1989352 0.0003239919 5.607486e-01 8.012137e-01 11 66057270 66057375 106 + 1.642 1.668 0.089
ENSG00000087365 E029 44.2529950 0.0003167139 8.393049e-01 9.423602e-01 11 66058054 66058150 97 + 1.659 1.650 -0.031
ENSG00000087365 E030 49.9979236 0.0002999318 4.131828e-03 4.344824e-02 11 66058314 66058405 92 + 1.759 1.636 -0.417
ENSG00000087365 E031 2.5567574 0.1664417413 6.489240e-01 8.519734e-01 11 66058406 66058603 198 + 0.586 0.503 -0.389
ENSG00000087365 E032 2.5881742 0.0743856247 3.039954e-01 5.974953e-01 11 66058607 66058829 223 + 0.474 0.631 0.728
ENSG00000087365 E033 110.8576185 0.0018073464 3.855960e-01 6.715340e-01 11 66058830 66059045 216 + 2.061 2.032 -0.096
ENSG00000087365 E034 97.0954815 0.0027337027 4.899716e-01 7.527542e-01 11 66059201 66059338 138 + 1.979 2.004 0.084
ENSG00000087365 E035 82.8290855 0.0002337227 9.314560e-01 9.799920e-01 11 66059515 66059595 81 + 1.921 1.924 0.010
ENSG00000087365 E036 150.6249457 0.0001194183 4.635556e-01 7.333943e-01 11 66059782 66060009 228 + 2.171 2.189 0.060
ENSG00000087365 E037 100.7426008 0.0001872626 9.181828e-01 9.743084e-01 11 66060582 66060690 109 + 2.008 2.005 -0.010
ENSG00000087365 E038 58.2880774 0.0002506430 1.763184e-01 4.504692e-01 11 66060691 66060731 41 + 1.796 1.743 -0.180
ENSG00000087365 E039 102.7909580 0.0001617094 4.668984e-01 7.355113e-01 11 66061686 66061775 90 + 2.005 2.027 0.072
ENSG00000087365 E040 109.1917141 0.0001591300 8.523389e-01 9.478202e-01 11 66061891 66061998 108 + 2.038 2.044 0.018
ENSG00000087365 E041 104.1471238 0.0021977771 8.637133e-01 9.528704e-01 11 66063009 66063116 108 + 2.023 2.018 -0.020
ENSG00000087365 E042 132.8278562 0.0012245742 9.373913e-01 9.820871e-01 11 66063400 66063542 143 + 2.125 2.127 0.007
ENSG00000087365 E043 102.4089365 0.0001475634 6.376812e-01 8.454664e-01 11 66063628 66063729 102 + 2.020 2.006 -0.046
ENSG00000087365 E044 13.7677121 0.0036160494 2.735384e-13 3.822027e-11 11 66064641 66067945 3305 + 0.766 1.398 2.313
ENSG00000087365 E045 52.1577671 0.0004993775 4.446630e-01 7.192003e-01 11 66067946 66067948 3 + 1.739 1.707 -0.108
ENSG00000087365 E046 99.5028606 0.0057323940 6.090204e-01 8.298656e-01 11 66067949 66068045 97 + 2.011 1.989 -0.072
ENSG00000087365 E047 138.7777504 0.0001297980 6.797101e-01 8.676709e-01 11 66068148 66068333 186 + 2.139 2.150 0.035
ENSG00000087365 E048 0.4795276 0.0277879639 4.377252e-01   11 66068334 66068673 340 + 0.220 0.105 -1.272
ENSG00000087365 E049 89.7784717 0.0009931053 2.894068e-01 5.830295e-01 11 66068674 66069308 635 + 1.940 1.976 0.120

Help

Please Click HERE to learn more details about the results from DEXseq.