ENSG00000087470

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000266481 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding protein_coding 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 1.937667 3.2117881 1.039100 1.6425308 1.0390997 -1.6187098 0.04039167 0.070300 0.018750 -0.051550 0.42131151 0.01314858 FALSE TRUE
ENST00000452533 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding protein_coding 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 12.987216 7.3596629 16.689575 2.4663012 5.8533545 1.1801409 0.25682500 0.151025 0.293700 0.142675 0.87518964 0.01314858 FALSE TRUE
ENST00000546757 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding nonsense_mediated_decay 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 2.104687 1.1284889 5.185572 1.1284889 5.1855721 2.1901624 0.03865000 0.025975 0.089975 0.064000 1.00000000 0.01314858 FALSE TRUE
ENST00000547312 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding protein_coding 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 3.004717 0.6787619 1.708196 0.6787619 0.8080769 1.3188177 0.06439167 0.013800 0.029900 0.016100 0.61355068 0.01314858 FALSE TRUE
ENST00000547640 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding retained_intron 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 7.642525 8.0452684 5.838321 0.9015058 1.2039809 -0.4619101 0.15483333 0.169525 0.102050 -0.067475 0.54979419 0.01314858 FALSE FALSE
ENST00000549157 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding retained_intron 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 4.819744 4.5747842 8.214463 1.5539984 0.9383154 0.8430677 0.09077500 0.093700 0.144550 0.050850 0.80077320 0.01314858   FALSE
ENST00000549701 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding protein_coding 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 5.938002 4.0919041 10.115001 1.5378450 2.2821220 1.3035563 0.11200833 0.084225 0.176175 0.091950 0.61887109 0.01314858 FALSE TRUE
ENST00000553031 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding retained_intron 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 4.463619 8.3433130 2.642306 0.8750296 0.4955364 -1.6551013 0.09139167 0.175925 0.046800 -0.129125 0.01314858 0.01314858 FALSE FALSE
ENST00000703362 ENSG00000087470 No_inf pgKDN_inf DNM1L protein_coding nonsense_mediated_decay 50.18609 47.40268 57.08296 1.504291 1.153606 0.2680399 2.260756 4.1315266 0.000000 1.4167090 0.0000000 -8.6940188 0.05041667 0.089225 0.000000 -0.089225 0.01746683 0.01314858 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000087470 E001 0.0000000       12 32679200 32679232 33 +      
ENSG00000087470 E002 0.0000000       12 32679233 32679263 31 +      
ENSG00000087470 E003 0.0000000       12 32679264 32679265 2 +      
ENSG00000087470 E004 0.0000000       12 32679266 32679272 7 +      
ENSG00000087470 E005 0.0000000       12 32679273 32679278 6 +      
ENSG00000087470 E006 0.0000000       12 32679279 32679280 2 +      
ENSG00000087470 E007 0.1170040 1.168453e-02 6.835307e-01   12 32679281 32679284 4 + 0.085 0.000 -10.515
ENSG00000087470 E008 0.4719109 1.594264e-02 7.731303e-02   12 32679285 32679291 7 + 0.272 0.000 -14.630
ENSG00000087470 E009 1.4259950 9.111902e-03 6.826070e-03 6.203155e-02 12 32679292 32679300 9 + 0.530 0.106 -3.117
ENSG00000087470 E010 1.4259950 9.111902e-03 6.826070e-03 6.203155e-02 12 32679301 32679302 2 + 0.530 0.106 -3.117
ENSG00000087470 E011 2.7484901 5.138477e-03 7.384582e-03 6.548504e-02 12 32679303 32679315 13 + 0.710 0.323 -1.905
ENSG00000087470 E012 3.0026064 4.726844e-03 3.975128e-02 1.932218e-01 12 32679316 32679319 4 + 0.710 0.424 -1.320
ENSG00000087470 E013 3.2477515 4.395087e-03 5.461585e-02 2.327963e-01 12 32679320 32679322 3 + 0.728 0.467 -1.172
ENSG00000087470 E014 4.3347917 1.259684e-02 5.618876e-02 2.363504e-01 12 32679323 32679335 13 + 0.823 0.575 -1.036
ENSG00000087470 E015 5.9036358 2.475795e-03 2.785544e-02 1.558460e-01 12 32679336 32679363 28 + 0.935 0.687 -0.979
ENSG00000087470 E016 7.8832214 2.347781e-03 2.526066e-01 5.441173e-01 12 32679364 32679408 45 + 0.996 0.882 -0.430
ENSG00000087470 E017 7.6474287 2.080044e-03 3.468563e-01 6.375187e-01 12 32679409 32679465 57 + 0.977 0.882 -0.358
ENSG00000087470 E018 0.0000000       12 32679594 32679684 91 +      
ENSG00000087470 E019 0.0000000       12 32679685 32679728 44 +      
ENSG00000087470 E020 0.0000000       12 32679729 32679745 17 +      
ENSG00000087470 E021 0.1186381 1.180045e-02 6.835236e-01   12 32679746 32679987 242 + 0.085 0.000 -12.757
ENSG00000087470 E022 10.0602323 2.057932e-03 1.513792e-01 4.147355e-01 12 32701415 32701472 58 + 1.098 0.967 -0.478
ENSG00000087470 E023 15.6350408 8.701282e-04 8.254585e-02 2.959461e-01 12 32701473 32701562 90 + 1.275 1.145 -0.460
ENSG00000087470 E024 0.2442663 1.623450e-02 8.517898e-01   12 32705825 32705863 39 + 0.085 0.106 0.343
ENSG00000087470 E025 1.2510051 1.090700e-02 2.124343e-02 1.318158e-01 12 32705864 32706237 374 + 0.157 0.506 2.343
ENSG00000087470 E026 0.6265274 1.828050e-01 1.547383e-01 4.202456e-01 12 32706238 32706569 332 + 0.085 0.323 2.343
ENSG00000087470 E027 0.1170040 1.168453e-02 6.835307e-01   12 32706570 32706642 73 + 0.085 0.000 -12.758
ENSG00000087470 E028 0.0000000       12 32706643 32706689 47 +      
ENSG00000087470 E029 0.1268540 1.227321e-02 4.213966e-01   12 32706690 32706814 125 + 0.000 0.106 12.251
ENSG00000087470 E030 1.1241173 1.280043e-02 4.114455e-02 1.968326e-01 12 32706815 32707366 552 + 0.157 0.467 2.150
ENSG00000087470 E031 11.1322868 6.928808e-02 3.846755e-01 6.707756e-01 12 32707367 32707413 47 + 1.140 1.004 -0.493
ENSG00000087470 E032 14.8335452 9.865756e-04 8.482608e-04 1.321112e-02 12 32708153 32708224 72 + 1.299 1.038 -0.930
ENSG00000087470 E033 0.6261159 1.487180e-02 1.043789e-01 3.376996e-01 12 32709544 32709607 64 + 0.085 0.323 2.343
ENSG00000087470 E034 19.2417896 7.058684e-04 6.221442e-03 5.794530e-02 12 32710929 32711015 87 + 1.381 1.193 -0.657
ENSG00000087470 E035 0.4977836 3.540320e-02 2.210715e-01   12 32711180 32711272 93 + 0.085 0.262 1.928
ENSG00000087470 E036 11.5363608 1.400440e-03 3.236540e-01 6.163343e-01 12 32713209 32713246 38 + 1.134 1.049 -0.306
ENSG00000087470 E037 26.0801918 5.180875e-04 8.731748e-01 9.567051e-01 12 32713247 32713371 125 + 1.436 1.425 -0.037
ENSG00000087470 E038 26.2404087 4.633158e-03 1.319558e-01 3.854348e-01 12 32718643 32718763 121 + 1.476 1.378 -0.337
ENSG00000087470 E039 27.1378965 1.007444e-03 4.141178e-01 6.944540e-01 12 32720664 32720795 132 + 1.469 1.421 -0.167
ENSG00000087470 E040 38.7993464 1.378283e-03 3.693855e-05 1.029583e-03 12 32722427 32722633 207 + 1.683 1.472 -0.718
ENSG00000087470 E041 0.1265070 1.226127e-02 4.214025e-01   12 32722634 32722772 139 + 0.000 0.106 12.252
ENSG00000087470 E042 0.0000000       12 32730988 32731013 26 +      
ENSG00000087470 E043 39.2416860 4.096542e-04 5.248248e-02 2.276858e-01 12 32731014 32731134 121 + 1.644 1.550 -0.321
ENSG00000087470 E044 44.4592518 3.335767e-04 5.499317e-01 7.945995e-01 12 32731356 32731511 156 + 1.669 1.641 -0.095
ENSG00000087470 E045 27.9630414 5.309055e-04 5.740160e-01 8.091164e-01 12 32731854 32731943 90 + 1.446 1.476 0.103
ENSG00000087470 E046 0.1271363 1.235506e-02 4.212984e-01   12 32732538 32732610 73 + 0.000 0.106 12.251
ENSG00000087470 E047 1.0984387 1.047709e-02 9.788108e-01 9.971889e-01 12 32733453 32733565 113 + 0.319 0.323 0.021
ENSG00000087470 E048 0.8798202 1.665208e-02 2.406735e-02 1.420495e-01 12 32733566 32733714 149 + 0.085 0.424 2.928
ENSG00000087470 E049 15.4551280 9.762450e-04 8.980222e-02 3.112721e-01 12 32733715 32733807 93 + 1.154 1.277 0.434
ENSG00000087470 E050 0.0000000       12 32737105 32737161 57 +      
ENSG00000087470 E051 0.0000000       12 32737162 32737306 145 +      
ENSG00000087470 E052 5.3327932 4.653559e-02 5.979238e-01 8.236606e-01 12 32737865 32737942 78 + 0.837 0.755 -0.323
ENSG00000087470 E053 3.0308776 1.089305e-01 7.766000e-01 9.141635e-01 12 32737943 32737976 34 + 0.629 0.575 -0.241
ENSG00000087470 E054 5.8624650 1.222358e-02 6.030748e-01 8.268611e-01 12 32737977 32738053 77 + 0.808 0.866 0.223
ENSG00000087470 E055 8.8976494 1.909388e-03 9.777394e-01 9.966914e-01 12 32738054 32738263 210 + 0.996 0.992 -0.015
ENSG00000087470 E056 12.6188252 3.497549e-02 4.035030e-01 6.864715e-01 12 32738264 32738296 33 + 1.173 1.080 -0.334
ENSG00000087470 E057 7.4330061 1.890434e-03 4.669698e-04 8.290174e-03 12 32739845 32740063 219 + 0.728 1.080 1.343
ENSG00000087470 E058 31.2901672 4.759858e-04 5.217113e-01 7.754926e-01 12 32740064 32740153 90 + 1.524 1.488 -0.121
ENSG00000087470 E059 38.8667499 6.426300e-04 5.454975e-01 7.914578e-01 12 32740154 32740240 87 + 1.613 1.582 -0.104
ENSG00000087470 E060 3.8284694 4.440669e-03 5.701297e-02 2.386526e-01 12 32740241 32740408 168 + 0.557 0.795 1.006
ENSG00000087470 E061 40.2192926 4.901255e-04 6.404079e-01 8.472896e-01 12 32740409 32740518 110 + 1.624 1.601 -0.080
ENSG00000087470 E062 51.6511823 4.057686e-04 7.250806e-01 8.896174e-01 12 32742589 32742748 160 + 1.727 1.711 -0.054
ENSG00000087470 E063 408.8920948 9.161235e-05 6.349769e-14 9.729217e-12 12 32743354 32745650 2297 + 2.569 2.656 0.288

Help

Please Click HERE to learn more details about the results from DEXseq.