ENSG00000088247

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000579148 ENSG00000088247 No_inf pgKDN_inf KHSRP protein_coding miRNA 101.9203 99.26297 95.42454 9.554276 2.638449 -0.05688937 2.474244 7.422733 0.00000 7.4227326 0.0000000 -9.53774890 0.02101667 0.063050 0.00000 -0.063050 9.173636e-01 6.948306e-20   FALSE
ENST00000594496 ENSG00000088247 No_inf pgKDN_inf KHSRP protein_coding protein_coding 101.9203 99.26297 95.42454 9.554276 2.638449 -0.05688937 15.319416 15.383987 10.89882 1.7418353 3.7704189 -0.49687245 0.14895833 0.158500 0.11130 -0.047200 8.251358e-01 6.948306e-20 FALSE FALSE
ENST00000597656 ENSG00000088247 No_inf pgKDN_inf KHSRP protein_coding protein_coding 101.9203 99.26297 95.42454 9.554276 2.638449 -0.05688937 3.741209 11.223627 0.00000 8.0399027 0.0000000 -10.13360807 0.03272500 0.098175 0.00000 -0.098175 7.463373e-01 6.948306e-20 FALSE FALSE
ENST00000600480 ENSG00000088247 No_inf pgKDN_inf KHSRP protein_coding protein_coding 101.9203 99.26297 95.42454 9.554276 2.638449 -0.05688937 65.191507 61.846070 65.93746 0.6915201 0.7901651 0.09240185 0.64840000 0.641850 0.69245 0.050600 8.430683e-01 6.948306e-20 FALSE TRUE
MSTRG.14382.4 ENSG00000088247 No_inf pgKDN_inf KHSRP protein_coding   101.9203 99.26297 95.42454 9.554276 2.638449 -0.05688937 9.730015 0.000000 13.54743 0.0000000 0.6938788 10.40486848 0.09448333 0.000000 0.14265 0.142650 6.948306e-20 6.948306e-20 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000088247 E001 33.6772288 1.199878e-02 0.0779034298 0.285550687 19 6413102 6413347 246 - 1.476 1.597 0.416
ENSG00000088247 E002 41.2202637 4.412892e-04 0.0008663758 0.013423474 19 6413348 6413410 63 - 1.541 1.698 0.532
ENSG00000088247 E003 64.3232491 2.930132e-04 0.1303070966 0.382980626 19 6413411 6413549 139 - 1.786 1.843 0.191
ENSG00000088247 E004 63.4667823 2.397848e-04 0.1420240595 0.400938269 19 6413550 6413640 91 - 1.781 1.836 0.186
ENSG00000088247 E005 89.8652692 3.531217e-04 0.0021265743 0.026773859 19 6413641 6413738 98 - 1.907 2.005 0.331
ENSG00000088247 E006 144.2923131 2.114349e-04 0.0005615564 0.009564116 19 6413739 6413964 226 - 2.117 2.204 0.289
ENSG00000088247 E007 53.1731587 2.992165e-04 0.8624628749 0.952543793 19 6413965 6414120 156 - 1.737 1.730 -0.024
ENSG00000088247 E008 226.0005499 8.774074e-04 0.1854154855 0.463124391 19 6414121 6414456 336 - 2.341 2.371 0.098
ENSG00000088247 E009 400.2361976 6.866752e-05 0.0411162020 0.196776998 19 6414457 6415140 684 - 2.589 2.618 0.096
ENSG00000088247 E010 54.1156085 1.984066e-03 0.7522095582 0.902416916 19 6415141 6415215 75 - 1.748 1.734 -0.047
ENSG00000088247 E011 71.5523267 2.225815e-03 0.7195835582 0.886923983 19 6415216 6415301 86 - 1.854 1.868 0.048
ENSG00000088247 E012 63.8329505 8.302502e-03 0.8951947090 0.965339027 19 6415380 6415457 78 - 1.809 1.815 0.020
ENSG00000088247 E013 0.8615704 1.563029e-02 0.6164043970 0.833691410 19 6415458 6415533 76 - 0.230 0.307 0.557
ENSG00000088247 E014 32.6690243 1.281471e-02 0.7901615396 0.919530757 19 6415534 6415608 75 - 1.517 1.537 0.067
ENSG00000088247 E015 45.4642791 6.692313e-03 0.9515735401 0.987838613 19 6415609 6415734 126 - 1.669 1.665 -0.013
ENSG00000088247 E016 48.8935229 6.819672e-04 0.9106321193 0.971670018 19 6415808 6415896 89 - 1.700 1.695 -0.017
ENSG00000088247 E017 50.4347305 3.231097e-03 0.1019552861 0.333547034 19 6416298 6416407 110 - 1.748 1.670 -0.265
ENSG00000088247 E018 0.3644125 2.252691e-01 0.6978691538   19 6416410 6416489 80 - 0.166 0.099 -0.859
ENSG00000088247 E019 84.5169475 2.088126e-04 0.6465849429 0.850387148 19 6416490 6416650 161 - 1.939 1.925 -0.050
ENSG00000088247 E020 85.0474266 2.300288e-03 0.2705445741 0.564234761 19 6416738 6416882 145 - 1.954 1.914 -0.136
ENSG00000088247 E021 92.6049301 1.986615e-03 0.6434362286 0.848818353 19 6416987 6417087 101 - 1.979 1.963 -0.056
ENSG00000088247 E022 96.5786925 3.071981e-04 0.3194657889 0.612145801 19 6417739 6417841 103 - 2.004 1.973 -0.103
ENSG00000088247 E023 58.4092053 3.239041e-04 0.1061312248 0.341027827 19 6417981 6418019 39 - 1.804 1.740 -0.215
ENSG00000088247 E024 57.4266883 2.843320e-04 0.0812465421 0.292911163 19 6418020 6418079 60 - 1.799 1.730 -0.234
ENSG00000088247 E025 66.6207860 2.200694e-04 0.0159936301 0.109647953 19 6418483 6418581 99 - 1.872 1.783 -0.299
ENSG00000088247 E026 0.0000000       19 6418701 6418701 1 -      
ENSG00000088247 E027 78.7550569 2.159810e-03 0.0106057363 0.083480704 19 6418702 6418876 175 - 1.948 1.849 -0.331
ENSG00000088247 E028 44.1044631 3.627181e-04 0.0912502161 0.313781405 19 6419203 6419260 58 - 1.690 1.614 -0.259
ENSG00000088247 E029 44.2735992 4.192808e-03 0.0292152484 0.160425087 19 6420073 6420144 72 - 1.708 1.594 -0.387
ENSG00000088247 E030 33.1258018 4.090456e-04 0.1071519576 0.343016007 19 6420422 6420471 50 - 1.572 1.489 -0.286
ENSG00000088247 E031 0.3802764 3.030066e-02 0.0874072273   19 6421001 6421277 277 - 0.000 0.248 11.172
ENSG00000088247 E032 27.7759008 5.188747e-03 0.3262729258 0.618779668 19 6421278 6421317 40 - 1.489 1.427 -0.214
ENSG00000088247 E033 2.0043177 2.104668e-02 0.0073025446 0.064958472 19 6421318 6421649 332 - 0.230 0.638 2.257
ENSG00000088247 E034 23.1404400 2.243113e-03 0.2462927311 0.536969527 19 6421650 6421688 39 - 1.418 1.344 -0.255
ENSG00000088247 E035 0.2536433 1.605136e-02 0.2105427932   19 6421689 6421698 10 - 0.000 0.180 10.811
ENSG00000088247 E036 27.6364779 5.601841e-04 0.0007704803 0.012279872 19 6422340 6422436 97 - 1.541 1.349 -0.663
ENSG00000088247 E037 0.2357071 1.569882e-02 0.2778514444   19 6422627 6422688 62 - 0.166 0.000 -11.441
ENSG00000088247 E038 0.0000000       19 6424138 6424216 79 -      
ENSG00000088247 E039 0.0000000       19 6424217 6424452 236 -      
ENSG00000088247 E040 18.8889046 9.671169e-04 0.0007174266 0.011560803 19 6424453 6424811 359 - 1.398 1.165 -0.817

Help

Please Click HERE to learn more details about the results from DEXseq.