ENSG00000088808

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000202556 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding protein_coding 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 2.3706318 3.2131973 2.4461020 0.59291327 0.22714484 -0.39212201 0.33750000 0.190250 0.492825 0.302575 0.1128075096 0.0004666853 FALSE TRUE
ENST00000554432 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding retained_intron 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 0.7354080 1.4058388 0.5400907 0.45849334 0.05531605 -1.36391560 0.08367500 0.081900 0.111375 0.029475 0.8442829106 0.0004666853   FALSE
ENST00000555391 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding protein_coding_CDS_not_defined 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 0.4526394 0.4405372 0.1169025 0.29737793 0.11690249 -1.82792600 0.08228333 0.027825 0.026850 -0.000975 1.0000000000 0.0004666853 FALSE TRUE
ENST00000555708 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding protein_coding_CDS_not_defined 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 0.2752825 0.8258476 0.0000000 0.40195365 0.00000000 -6.38516808 0.01731667 0.051950 0.000000 -0.051950 0.5342127045 0.0004666853   FALSE
ENST00000555825 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding retained_intron 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 0.5247613 1.0400262 0.2116375 0.16877126 0.12500491 -2.24415127 0.06121667 0.062950 0.046325 -0.016625 0.8496490830 0.0004666853 TRUE FALSE
ENST00000556597 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding nonsense_mediated_decay 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 1.5032924 3.4439796 0.0000000 0.31933722 0.00000000 -8.43211576 0.14905833 0.206175 0.000000 -0.206175 0.0009120172 0.0004666853 TRUE TRUE
ENST00000557082 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding nonsense_mediated_decay 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 0.3441785 0.1898576 0.6893592 0.05958725 0.18298235 1.80706117 0.06467500 0.011275 0.147475 0.136200 0.0446087268 0.0004666853 FALSE TRUE
ENST00000557587 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding nonsense_mediated_decay 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 0.5972759 0.8787766 0.9130510 0.87877662 0.91305097 0.05458945 0.05754167 0.057900 0.114725 0.056825 0.8531445545 0.0004666853 TRUE FALSE
ENST00000557744 ENSG00000088808 No_inf pgKDN_inf PPP1R13B protein_coding retained_intron 8.725255 16.64966 5.19438 0.6699336 0.9447551 -1.678561 1.4967575 4.4902724 0.0000000 0.86289673 0.00000000 -8.81386852 0.08849167 0.265475 0.000000 -0.265475 0.0004666853 0.0004666853   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000088808 E001 0.1271363 0.0123510694 1.000000e+00   14 103733195 103733751 557 - 0.000 0.063 9.335
ENSG00000088808 E002 0.1271363 0.0123510694 1.000000e+00   14 103733752 103733752 1 - 0.000 0.063 11.791
ENSG00000088808 E003 3.3598274 0.0047172054 9.100083e-01 0.971484834 14 103733753 103733922 170 - 0.608 0.600 -0.038
ENSG00000088808 E004 12.6991352 0.0315198362 9.597066e-01 0.990618640 14 103733923 103734366 444 - 1.082 1.095 0.045
ENSG00000088808 E005 17.7084489 0.0058162804 3.763062e-01 0.663474980 14 103734367 103734663 297 - 1.169 1.246 0.271
ENSG00000088808 E006 16.9831595 0.0008706937 1.656817e-01 0.435514006 14 103734664 103734891 228 - 1.122 1.238 0.414
ENSG00000088808 E007 2.7225148 0.0061044009 4.358207e-01 0.712267843 14 103734892 103734892 1 - 0.608 0.504 -0.479
ENSG00000088808 E008 5.3623594 0.0027555123 6.515137e-01 0.853257813 14 103734893 103734983 91 - 0.716 0.779 0.254
ENSG00000088808 E009 2.5218321 0.0060354644 4.235921e-02 0.200526766 14 103734984 103734999 16 - 0.247 0.582 1.884
ENSG00000088808 E010 5.1546271 0.0028174493 3.377119e-02 0.174897547 14 103735000 103735079 80 - 0.518 0.812 1.258
ENSG00000088808 E011 3.9040954 0.0044025199 3.697480e-02 0.185127984 14 103735080 103735113 34 - 0.403 0.719 1.468
ENSG00000088808 E012 5.3492928 0.0114838840 8.221357e-01 0.935493294 14 103735114 103735195 82 - 0.776 0.756 -0.080
ENSG00000088808 E013 10.2259488 0.0028856290 5.355537e-01 0.785276649 14 103736003 103736202 200 - 0.956 1.024 0.252
ENSG00000088808 E014 4.3990456 0.0034120382 4.432796e-02 0.205852700 14 103736203 103737693 1491 - 0.464 0.756 1.299
ENSG00000088808 E015 2.5060630 0.0518669393 4.306530e-01 0.708507263 14 103737694 103737710 17 - 0.403 0.545 0.714
ENSG00000088808 E016 7.4542440 0.0029835921 8.242001e-01 0.936174874 14 103737711 103737860 150 - 0.897 0.880 -0.064
ENSG00000088808 E017 2.2507861 0.0073780018 5.415945e-01 0.789234556 14 103738389 103738678 290 - 0.403 0.504 0.521
ENSG00000088808 E018 7.2789610 0.0023503354 8.796024e-02 0.307630517 14 103738679 103738812 134 - 0.991 0.822 -0.640
ENSG00000088808 E019 5.2102947 0.0031322208 5.093080e-01 0.767272840 14 103738886 103739023 138 - 0.803 0.731 -0.286
ENSG00000088808 E020 0.0000000       14 103739024 103739272 249 -      
ENSG00000088808 E021 9.0302160 0.0032695473 1.759851e-02 0.116532603 14 103739824 103740063 240 - 0.747 1.017 1.036
ENSG00000088808 E022 18.4271222 0.0008710341 6.477703e-01 0.851244129 14 103740064 103740593 530 - 1.212 1.253 0.147
ENSG00000088808 E023 6.3299377 0.0027172331 6.713634e-01 0.863648237 14 103741790 103741991 202 - 0.852 0.812 -0.157
ENSG00000088808 E024 3.8351080 0.0079578877 4.170136e-01 0.696747689 14 103741992 103742088 97 - 0.716 0.616 -0.424
ENSG00000088808 E025 8.4948546 0.0018797056 2.141444e-01 0.499358632 14 103742089 103742291 203 - 0.828 0.969 0.535
ENSG00000088808 E026 7.0835495 0.0112338621 8.365508e-01 0.941413330 14 103742654 103742823 170 - 0.875 0.861 -0.052
ENSG00000088808 E027 3.1758038 0.0074016778 9.909754e-05 0.002357621 14 103742824 103743078 255 - 0.000 0.692 15.562
ENSG00000088808 E028 0.9960376 0.0117908077 8.180010e-01 0.933772418 14 103743891 103744015 125 - 0.247 0.288 0.299
ENSG00000088808 E029 0.8409241 0.0338116101 2.255741e-02 0.136663327 14 103746373 103746373 1 - 0.464 0.118 -2.608
ENSG00000088808 E030 4.4296256 0.0033057923 4.485756e-02 0.207079053 14 103746374 103746553 180 - 0.852 0.616 -0.964
ENSG00000088808 E031 0.2530140 0.3636883031 9.196909e-01   14 103746652 103746707 56 - 0.000 0.118 12.406
ENSG00000088808 E032 0.3806233 0.0160639748 4.399879e-01   14 103746708 103746772 65 - 0.000 0.167 13.181
ENSG00000088808 E033 0.3806233 0.0160639748 4.399879e-01   14 103746773 103746860 88 - 0.000 0.167 13.181
ENSG00000088808 E034 1.3785160 0.0095077513 4.239518e-01 0.703178731 14 103746933 103747397 465 - 0.247 0.382 0.884
ENSG00000088808 E035 5.5461061 0.0171103553 6.631949e-02 0.259363027 14 103749794 103749934 141 - 0.917 0.705 -0.834
ENSG00000088808 E036 4.8995289 0.0029207808 4.593585e-03 0.046666114 14 103753000 103753196 197 - 0.937 0.616 -1.286
ENSG00000088808 E037 5.5119855 0.0234644515 4.553818e-03 0.046393207 14 103754070 103754164 95 - 0.991 0.648 -1.351
ENSG00000088808 E038 4.1669238 0.0380545542 2.249100e-02 0.136353803 14 103754165 103754238 74 - 0.875 0.564 -1.286
ENSG00000088808 E039 1.0981554 0.0115395532 9.540325e-02 0.321572336 14 103754239 103754244 6 - 0.464 0.211 -1.608
ENSG00000088808 E040 0.2454921 0.0162414031 4.751344e-01   14 103757649 103757649 1 - 0.141 0.063 -1.286
ENSG00000088808 E041 3.9636659 0.0036490956 4.844999e-01 0.748658336 14 103757650 103757751 102 - 0.716 0.633 -0.353
ENSG00000088808 E042 0.1268540 0.0123872355 1.000000e+00   14 103759191 103759305 115 - 0.000 0.063 11.791
ENSG00000088808 E043 1.6966044 0.0078085270 6.147073e-03 0.057499310 14 103763863 103764479 617 - 0.647 0.251 -2.134
ENSG00000088808 E044 0.1268540 0.0123872355 1.000000e+00   14 103778592 103778744 153 - 0.000 0.063 11.791
ENSG00000088808 E045 1.8779336 0.0074879535 4.453851e-01 0.719762129 14 103778745 103778754 10 - 0.332 0.459 0.714
ENSG00000088808 E046 3.1101514 0.0047185918 9.436283e-01 0.984402561 14 103778755 103778821 67 - 0.565 0.582 0.076
ENSG00000088808 E047 2.0940054 0.0070273734 2.726834e-01 0.566391008 14 103784795 103784914 120 - 0.565 0.409 -0.772
ENSG00000088808 E048 0.0000000       14 103794577 103794663 87 -      
ENSG00000088808 E049 1.1252227 0.0279594846 6.756531e-01 0.865656401 14 103797371 103797518 148 - 0.247 0.322 0.521
ENSG00000088808 E050 0.0000000       14 103840079 103840107 29 -      
ENSG00000088808 E051 0.0000000       14 103846775 103846885 111 -      
ENSG00000088808 E052 0.0000000       14 103847008 103847298 291 -      
ENSG00000088808 E053 2.8669206 0.0185670865 7.925995e-01 0.920857821 14 103847299 103847541 243 - 0.518 0.564 0.216
ENSG00000088808 E054 1.2433549 0.0100060438 9.272956e-01 0.978381594 14 103847542 103847575 34 - 0.332 0.322 -0.064

Help

Please Click HERE to learn more details about the results from DEXseq.