ENSG00000089053

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261819 ENSG00000089053 No_inf pgKDN_inf ANAPC5 protein_coding protein_coding 75.13263 68.07421 75.25283 6.983667 2.511909 0.1446173 21.468090 11.235252 26.982146 3.053908 1.991259 1.2632237 0.29312500 0.176500 0.361825 0.185325 2.792346e-01 4.870366e-09 FALSE TRUE
ENST00000441917 ENSG00000089053 No_inf pgKDN_inf ANAPC5 protein_coding protein_coding 75.13263 68.07421 75.25283 6.983667 2.511909 0.1446173 18.451789 12.085398 23.155902 4.136227 4.751658 0.9375446 0.25620000 0.188725 0.314025 0.125300 8.049956e-01 4.870366e-09 FALSE TRUE
ENST00000535463 ENSG00000089053 No_inf pgKDN_inf ANAPC5 protein_coding retained_intron 75.13263 68.07421 75.25283 6.983667 2.511909 0.1446173 4.615164 7.532707 0.000000 5.511038 0.000000 -9.5589386 0.05169167 0.099125 0.000000 -0.099125 4.575804e-01 4.870366e-09   FALSE
ENST00000538223 ENSG00000089053 No_inf pgKDN_inf ANAPC5 protein_coding protein_coding_CDS_not_defined 75.13263 68.07421 75.25283 6.983667 2.511909 0.1446173 5.008443 5.572664 0.000000 1.273396 0.000000 -9.1248099 0.06327500 0.080375 0.000000 -0.080375 4.870366e-09 4.870366e-09   FALSE
ENST00000541652 ENSG00000089053 No_inf pgKDN_inf ANAPC5 protein_coding retained_intron 75.13263 68.07421 75.25283 6.983667 2.511909 0.1446173 4.851985 5.805494 3.335083 4.834509 3.335083 -0.7978595 0.05817500 0.077875 0.041225 -0.036650 8.429271e-01 4.870366e-09 FALSE TRUE
ENST00000544314 ENSG00000089053 No_inf pgKDN_inf ANAPC5 protein_coding protein_coding_CDS_not_defined 75.13263 68.07421 75.25283 6.983667 2.511909 0.1446173 5.109834 2.524300 9.106310 1.962121 3.531985 1.8468624 0.06122500 0.034300 0.116600 0.082300 5.925449e-01 4.870366e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000089053 E001 0.3706473 0.0166645447 4.275166e-01   12 121308245 121308331 87 - 0.084 0.194 1.401
ENSG00000089053 E002 0.7438752 0.0138881125 2.514864e-01 5.426023e-01 12 121308332 121308356 25 - 0.154 0.327 1.401
ENSG00000089053 E003 0.8703822 0.0133796361 1.349405e-01 3.905281e-01 12 121308357 121308357 1 - 0.154 0.381 1.723
ENSG00000089053 E004 93.9534011 0.0012263337 8.822835e-01 9.604482e-01 12 121308358 121308691 334 - 1.973 1.979 0.021
ENSG00000089053 E005 73.8401931 0.0019570761 9.050682e-01 9.695503e-01 12 121309701 121309863 163 - 1.873 1.870 -0.011
ENSG00000089053 E006 2.2465047 0.1848542431 2.941190e-02 1.611472e-01 12 121309864 121309969 106 - 0.268 0.693 2.209
ENSG00000089053 E007 2.1029105 0.0074458901 7.864956e-02 2.874490e-01 12 121309970 121310011 42 - 0.358 0.612 1.276
ENSG00000089053 E008 5.4476574 0.0284276853 7.558100e-03 6.652066e-02 12 121310012 121310394 383 - 0.623 0.962 1.352
ENSG00000089053 E009 1.4513031 0.0087556921 4.901571e-01 7.528230e-01 12 121317890 121318154 265 - 0.432 0.327 -0.599
ENSG00000089053 E010 48.3492385 0.0017450199 1.280157e-01 3.791760e-01 12 121318277 121318351 75 - 1.721 1.652 -0.232
ENSG00000089053 E011 43.0057703 0.0076491827 2.301486e-01 5.186940e-01 12 121318352 121318404 53 - 1.670 1.603 -0.228
ENSG00000089053 E012 35.5768224 0.0140868048 2.400014e-01 5.292002e-01 12 121318405 121318424 20 - 1.595 1.516 -0.270
ENSG00000089053 E013 3.9454375 0.0034851751 6.929892e-02 2.660448e-01 12 121318425 121318500 76 - 0.576 0.802 0.949
ENSG00000089053 E014 45.0900239 0.0010715302 2.102189e-01 4.946113e-01 12 121318501 121318534 34 - 1.686 1.630 -0.190
ENSG00000089053 E015 46.9610905 0.0079649138 5.590486e-01 8.004060e-01 12 121318535 121318608 74 - 1.693 1.660 -0.112
ENSG00000089053 E016 54.1189790 0.0004730554 9.814424e-01 9.982107e-01 12 121319697 121319818 122 - 1.738 1.740 0.009
ENSG00000089053 E017 40.2217355 0.0004001691 9.574699e-01 9.898200e-01 12 121320385 121320459 75 - 1.611 1.615 0.014
ENSG00000089053 E018 0.7364767 0.0146169132 7.397444e-01 8.968699e-01 12 121320460 121321111 652 - 0.215 0.266 0.401
ENSG00000089053 E019 0.2448930 0.0164052816 8.312611e-01   12 121326353 121326485 133 - 0.084 0.108 0.401
ENSG00000089053 E020 0.2352613 0.2644962782 4.167102e-01   12 121326486 121326642 157 - 0.154 0.000 -9.946
ENSG00000089053 E021 47.2680297 0.0003051899 7.917513e-01 9.203481e-01 12 121327096 121327231 136 - 1.686 1.676 -0.033
ENSG00000089053 E022 22.4942438 0.0064865749 6.531491e-11 6.709894e-09 12 121327232 121328256 1025 - 1.097 1.565 1.635
ENSG00000089053 E023 2.3571483 0.0410665421 4.248852e-02 2.008568e-01 12 121328257 121328315 59 - 0.358 0.668 1.517
ENSG00000089053 E024 58.9540787 0.0037657410 7.506111e-01 9.016762e-01 12 121328316 121328458 143 - 1.781 1.768 -0.044
ENSG00000089053 E025 23.3444315 0.0206840563 5.826751e-01 8.140817e-01 12 121328459 121328497 39 - 1.403 1.361 -0.146
ENSG00000089053 E026 1.6331047 0.0091942738 2.262338e-03 2.803698e-02 12 121328773 121328835 63 - 0.154 0.612 2.861
ENSG00000089053 E027 1.3673762 0.0095877491 4.999210e-02 2.207164e-01 12 121328999 121329185 187 - 0.215 0.512 1.816
ENSG00000089053 E028 39.5863093 0.0093844293 3.411575e-01 6.327587e-01 12 121330583 121330672 90 - 1.578 1.638 0.205
ENSG00000089053 E029 7.3425366 0.0100895265 4.486830e-05 1.220019e-03 12 121330673 121331226 554 - 0.665 1.108 1.706
ENSG00000089053 E030 1.6345866 0.0085660543 2.237458e-03 2.782455e-02 12 121331227 121331346 120 - 0.154 0.612 2.861
ENSG00000089053 E031 35.2320823 0.0006385977 9.181999e-02 3.146864e-01 12 121331347 121331428 82 - 1.592 1.508 -0.288
ENSG00000089053 E032 22.8367199 0.0034941623 7.836919e-11 8.005235e-09 12 121331429 121335172 3744 - 1.126 1.562 1.521
ENSG00000089053 E033 1.0053229 0.0780789937 1.548816e-02 1.074943e-01 12 121335517 121335532 16 - 0.084 0.473 3.208
ENSG00000089053 E034 67.0878322 0.0003302668 4.890960e-01 7.521300e-01 12 121335533 121335723 191 - 1.841 1.818 -0.080
ENSG00000089053 E035 42.9456951 0.0022596204 4.493512e-01 7.231560e-01 12 121337291 121337392 102 - 1.656 1.621 -0.119
ENSG00000089053 E036 0.0000000       12 121337393 121337395 3 -      
ENSG00000089053 E037 38.3711533 0.0003497883 7.628109e-02 2.822994e-01 12 121342003 121342069 67 - 1.629 1.544 -0.287
ENSG00000089053 E038 0.0000000       12 121342070 121342071 2 -      
ENSG00000089053 E039 22.3406034 0.0006424726 1.587467e-01 4.258339e-01 12 121345839 121345839 1 - 1.403 1.316 -0.302
ENSG00000089053 E040 40.2993312 0.0003657714 3.014993e-02 1.633598e-01 12 121345840 121345923 84 - 1.656 1.555 -0.345
ENSG00000089053 E041 20.0917810 0.0009024930 6.110705e-01 8.308705e-01 12 121345924 121345951 28 - 1.336 1.304 -0.111
ENSG00000089053 E042 24.4615153 0.0005601777 1.359206e-02 9.812250e-02 12 121345952 121345998 47 - 1.464 1.316 -0.514
ENSG00000089053 E043 22.5261946 0.0027241703 4.127948e-02 1.972681e-01 12 121345999 121346031 33 - 1.424 1.291 -0.461
ENSG00000089053 E044 2.2057185 0.0061939686 5.665749e-01 8.047037e-01 12 121346032 121346035 4 - 0.465 0.548 0.401
ENSG00000089053 E045 3.8992418 0.0035738370 9.494008e-01 9.867987e-01 12 121346036 121346126 91 - 0.684 0.694 0.039
ENSG00000089053 E046 12.3634200 0.0011815856 2.060094e-01 4.895538e-01 12 121346127 121346794 668 - 1.074 1.178 0.373
ENSG00000089053 E047 2.4490149 0.0060459857 5.464698e-01 7.922291e-01 12 121346795 121346895 101 - 0.496 0.581 0.401
ENSG00000089053 E048 32.2330340 0.0042649431 5.449317e-01 7.910820e-01 12 121346896 121347005 110 - 1.534 1.500 -0.116
ENSG00000089053 E049 0.7355979 0.0134530928 7.400850e-01 8.968699e-01 12 121347006 121347801 796 - 0.215 0.266 0.401
ENSG00000089053 E050 21.2809189 0.0024081202 2.505439e-01 5.417042e-01 12 121347802 121347881 80 - 1.309 1.386 0.268
ENSG00000089053 E051 0.1272623 0.0123584937 4.070756e-01   12 121347882 121347883 2 - 0.000 0.108 9.643
ENSG00000089053 E052 0.0000000       12 121351060 121351203 144 -      
ENSG00000089053 E053 30.8010058 0.0004462110 6.782943e-01 8.668165e-01 12 121352134 121352426 293 - 1.509 1.489 -0.071
ENSG00000089053 E054 0.0000000       12 121399611 121399896 286 -      

Help

Please Click HERE to learn more details about the results from DEXseq.