ENSG00000089060

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000550672 ENSG00000089060 No_inf pgKDN_inf SLC8B1 protein_coding nonsense_mediated_decay 14.5169 11.60864 12.83123 0.7783544 1.307466 0.1443424 0.3426520 0.8139061 0.0000000 0.1780424 0.0000000 -6.36440799 0.02731667 0.070875 0.000000 -0.070875 0.02708215 0.02708215 TRUE  
ENST00000552014 ENSG00000089060 No_inf pgKDN_inf SLC8B1 protein_coding protein_coding 14.5169 11.60864 12.83123 0.7783544 1.307466 0.1443424 0.4875597 1.4626790 0.0000000 1.4626790 0.0000000 -7.20229920 0.04101667 0.123050 0.000000 -0.123050 0.84868099 0.02708215 FALSE  
ENST00000552565 ENSG00000089060 No_inf pgKDN_inf SLC8B1 protein_coding retained_intron 14.5169 11.60864 12.83123 0.7783544 1.307466 0.1443424 2.4611183 2.1091871 2.0497838 0.3498121 0.7939640 -0.04101804 0.17014167 0.179550 0.162550 -0.017000 0.88622278 0.02708215 FALSE  
ENST00000680972 ENSG00000089060 No_inf pgKDN_inf SLC8B1 protein_coding protein_coding 14.5169 11.60864 12.83123 0.7783544 1.307466 0.1443424 7.4825578 3.2214810 8.6936518 1.8660384 0.8988410 1.42942532 0.51295833 0.309475 0.677675 0.368200 0.44264541 0.02708215 FALSE  
MSTRG.7246.1 ENSG00000089060 No_inf pgKDN_inf SLC8B1 protein_coding   14.5169 11.60864 12.83123 0.7783544 1.307466 0.1443424 1.0814364 1.7243523 0.5928329 1.3250011 0.4808347 -1.52456700 0.07727500 0.130200 0.051925 -0.078275 0.86415672 0.02708215 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000089060 E001 0.6250132 0.0170716034 1.785494e-01 0.4534409002 12 113298613 113298758 146 - 0.094 0.298 2.020
ENSG00000089060 E002 0.3798680 0.0185057567 1.060357e-01   12 113298759 113298766 8 - 0.000 0.240 13.738
ENSG00000089060 E003 0.3798680 0.0185057567 1.060357e-01   12 113298767 113298770 4 - 0.000 0.240 13.738
ENSG00000089060 E004 0.3798680 0.0185057567 1.060357e-01   12 113298771 113298772 2 - 0.000 0.240 13.738
ENSG00000089060 E005 0.3798680 0.0185057567 1.060357e-01   12 113298773 113298776 4 - 0.000 0.240 13.738
ENSG00000089060 E006 0.3798680 0.0185057567 1.060357e-01   12 113298777 113298780 4 - 0.000 0.240 13.738
ENSG00000089060 E007 33.2509406 0.0004308839 3.284854e-01 0.6210162469 12 113298781 113299331 551 - 1.553 1.516 -0.129
ENSG00000089060 E008 31.7552621 0.0007510014 1.702130e-01 0.4423586295 12 113299332 113299776 445 - 1.544 1.485 -0.202
ENSG00000089060 E009 21.0257486 0.0008021906 3.180841e-01 0.6108220335 12 113299777 113299974 198 - 1.369 1.316 -0.182
ENSG00000089060 E010 1.7782120 0.0107208366 3.053939e-05 0.0008770834 12 113302140 113302700 561 - 0.000 0.648 15.574
ENSG00000089060 E011 10.3222282 0.0085756254 5.676831e-01 0.8054036490 12 113304321 113304385 65 - 1.020 1.082 0.226
ENSG00000089060 E012 11.9591433 0.0013953082 5.844652e-02 0.2421272534 12 113306495 113306575 81 - 1.020 1.185 0.593
ENSG00000089060 E013 0.8628315 0.3005323590 6.866151e-01 0.8705723341 12 113306576 113306844 269 - 0.238 0.298 0.433
ENSG00000089060 E014 11.5533458 0.0013545279 3.222789e-01 0.6153286624 12 113307691 113307799 109 - 1.050 1.140 0.328
ENSG00000089060 E015 5.8858402 0.0060492936 8.034654e-01 0.9269321699 12 113307800 113307844 45 - 0.819 0.855 0.140
ENSG00000089060 E016 0.2451451 0.0161289773 9.929649e-01   12 113307845 113307912 68 - 0.094 0.096 0.020
ENSG00000089060 E017 1.6309680 0.0122208087 1.041992e-02 0.0824876233 12 113307913 113308843 931 - 0.172 0.570 2.480
ENSG00000089060 E018 11.2480811 0.0078045780 6.535236e-01 0.8544347772 12 113310234 113310355 122 - 1.103 1.074 -0.105
ENSG00000089060 E019 3.7846300 0.0255302147 6.061358e-01 0.8284944899 12 113315335 113315341 7 - 0.710 0.648 -0.260
ENSG00000089060 E020 9.6020953 0.0015233309 2.726119e-01 0.5662861174 12 113315342 113315476 135 - 0.967 1.074 0.392
ENSG00000089060 E021 7.1620623 0.0088128003 8.322498e-02 0.2972816817 12 113316526 113316624 99 - 0.803 0.994 0.731
ENSG00000089060 E022 3.9077789 0.0038324469 7.069758e-01 0.8811692556 12 113316625 113316656 32 - 0.710 0.672 -0.160
ENSG00000089060 E023 5.1345522 0.0347155377 9.949307e-01 1.0000000000 12 113316942 113317001 60 - 0.785 0.791 0.021
ENSG00000089060 E024 8.1622413 0.0299360254 4.524927e-01 0.7256795704 12 113318964 113319071 108 - 1.000 0.924 -0.282
ENSG00000089060 E025 1.5938053 0.0312429630 7.941778e-01 0.9214964557 12 113319072 113319325 254 - 0.391 0.435 0.243
ENSG00000089060 E026 1.4602056 0.0101875725 5.545526e-01 0.7972862273 12 113319974 113320330 357 - 0.432 0.349 -0.465
ENSG00000089060 E027 4.0521561 0.0038380490 6.245330e-01 0.8384955700 12 113320331 113320360 30 - 0.667 0.735 0.283
ENSG00000089060 E028 8.7557899 0.0418358511 2.666038e-01 0.5600788087 12 113320361 113320498 138 - 1.049 0.924 -0.464
ENSG00000089060 E029 1.1069979 0.0105486326 7.517157e-01 0.9021952541 12 113320499 113320580 82 - 0.295 0.349 0.342
ENSG00000089060 E030 6.3588313 0.0031722471 7.585102e-01 0.9051660199 12 113320581 113320686 106 - 0.879 0.855 -0.091
ENSG00000089060 E031 1.1150205 0.0181799732 3.305541e-01 0.6230770040 12 113320687 113320849 163 - 0.238 0.394 1.020
ENSG00000089060 E032 3.5559533 0.0055620625 8.723765e-01 0.9564008276 12 113320850 113320875 26 - 0.644 0.672 0.120
ENSG00000089060 E033 4.8738241 0.0030097518 3.308365e-01 0.6231525203 12 113320876 113320907 32 - 0.819 0.715 -0.416
ENSG00000089060 E034 6.5725136 0.0135281957 2.032952e-01 0.4858007781 12 113321056 113321108 53 - 0.943 0.808 -0.521
ENSG00000089060 E035 9.2306279 0.0329497201 4.284453e-01 0.7069278427 12 113321196 113321348 153 - 0.955 1.055 0.367
ENSG00000089060 E036 3.8091481 0.0039441834 6.131775e-01 0.8318103924 12 113332723 113332748 26 - 0.644 0.715 0.300
ENSG00000089060 E037 11.2865132 0.0106618182 8.765551e-01 0.9581408566 12 113332749 113332960 212 - 1.077 1.100 0.082
ENSG00000089060 E038 12.2409892 0.0020785822 6.613478e-01 0.8587109137 12 113334443 113334671 229 - 1.135 1.108 -0.095
ENSG00000089060 E039 7.9002873 0.0018327884 5.683444e-02 0.2380822154 12 113334672 113334835 164 - 1.030 0.855 -0.658
ENSG00000089060 E040 2.0597887 0.0163286243 2.242941e-01 0.5118289068 12 113334836 113334838 3 - 0.565 0.394 -0.854
ENSG00000089060 E041 6.0972147 0.0084405707 3.915639e-01 0.6766677315 12 113334839 113334992 154 - 0.892 0.808 -0.328
ENSG00000089060 E042 4.8130922 0.0055567314 1.623213e-01 0.4307325694 12 113334993 113335174 182 - 0.667 0.840 0.698
ENSG00000089060 E043 0.0000000       12 113338226 113338494 269 -      
ENSG00000089060 E044 0.0000000       12 113353675 113353768 94 -      
ENSG00000089060 E045 0.0000000       12 113359330 113359493 164 -      

Help

Please Click HERE to learn more details about the results from DEXseq.