ENSG00000089154

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000300648 ENSG00000089154 No_inf pgKDN_inf GCN1 protein_coding protein_coding 29.28352 24.35019 29.18145 0.6669618 0.9702339 0.2610204 8.450777 4.795008 10.4128278 0.5958812 0.6846716 1.1171359 0.28423333 0.196675 0.360150 0.163475 0.2334815 0.0493948 FALSE  
ENST00000547369 ENSG00000089154 No_inf pgKDN_inf GCN1 protein_coding retained_intron 29.28352 24.35019 29.18145 0.6669618 0.9702339 0.2610204 1.147539 1.659556 0.0000000 0.6477374 0.0000000 -7.3833203 0.04042500 0.068875 0.000000 -0.068875 0.0493948 0.0493948 FALSE  
ENST00000551549 ENSG00000089154 No_inf pgKDN_inf GCN1 protein_coding retained_intron 29.28352 24.35019 29.18145 0.6669618 0.9702339 0.2610204 2.167222 3.846182 0.8237021 1.4945120 0.8237021 -2.2095694 0.07661667 0.156450 0.025775 -0.130675 0.3008857 0.0493948    
MSTRG.7294.11 ENSG00000089154 No_inf pgKDN_inf GCN1 protein_coding   29.28352 24.35019 29.18145 0.6669618 0.9702339 0.2610204 1.097767 1.833806 0.4794211 0.2738892 0.2768332 -1.9135390 0.04049167 0.075700 0.016750 -0.058950 0.2704137 0.0493948 FALSE  
MSTRG.7294.2 ENSG00000089154 No_inf pgKDN_inf GCN1 protein_coding   29.28352 24.35019 29.18145 0.6669618 0.9702339 0.2610204 15.090937 11.295505 16.5479858 0.9583071 0.3583882 0.5505017 0.51618333 0.465625 0.567925 0.102300 0.6386164 0.0493948 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000089154 E001 0.8696264 0.0131866734 9.295976e-02 0.3167153263 12 120127202 120127283 82 - 0.145 0.400 1.926
ENSG00000089154 E002 133.7431676 0.0003082553 2.377712e-01 0.5267375981 12 120127284 120127974 691 - 2.110 2.141 0.103
ENSG00000089154 E003 55.1600781 0.0061200557 6.742139e-01 0.8650043502 12 120129276 120129494 219 - 1.751 1.731 -0.069
ENSG00000089154 E004 38.1385612 0.0005114447 6.688440e-01 0.8621962928 12 120130646 120130753 108 - 1.595 1.574 -0.069
ENSG00000089154 E005 41.0315597 0.0003479466 3.062190e-01 0.5993256339 12 120131185 120131333 149 - 1.597 1.645 0.164
ENSG00000089154 E006 22.4370028 0.0006426630 2.361794e-01 0.5254187834 12 120131926 120132022 97 - 1.331 1.406 0.258
ENSG00000089154 E007 18.9083645 0.0025806672 3.111087e-01 0.6042904874 12 120134291 120134405 115 - 1.262 1.333 0.249
ENSG00000089154 E008 15.4584480 0.0012222603 7.792462e-01 0.9149983786 12 120134533 120134599 67 - 1.201 1.223 0.076
ENSG00000089154 E009 22.1489607 0.0035346180 8.033407e-01 0.9269321699 12 120134600 120134726 127 - 1.351 1.368 0.059
ENSG00000089154 E010 32.7087069 0.0004430997 7.864829e-01 0.9177845919 12 120136502 120136732 231 - 1.515 1.530 0.051
ENSG00000089154 E011 21.9118885 0.0006404273 4.941395e-01 0.7557343870 12 120137206 120137319 114 - 1.335 1.379 0.152
ENSG00000089154 E012 0.1272623 0.0123441688 3.493542e-01   12 120137320 120137390 71 - 0.000 0.115 12.052
ENSG00000089154 E013 42.1214563 0.0036101053 2.905372e-01 0.5840631801 12 120137545 120137814 270 - 1.605 1.660 0.185
ENSG00000089154 E014 24.4594344 0.0005674953 5.488327e-01 0.7936706892 12 120137901 120138015 115 - 1.384 1.421 0.126
ENSG00000089154 E015 12.3612173 0.0012324576 3.620956e-01 0.6513597729 12 120138016 120138044 29 - 1.149 1.074 -0.270
ENSG00000089154 E016 20.7577039 0.0007307162 5.407220e-01 0.7886341679 12 120138323 120138415 93 - 1.347 1.308 -0.137
ENSG00000089154 E017 26.6134647 0.0138730018 8.889779e-01 0.9630018335 12 120138695 120138856 162 - 1.438 1.431 -0.025
ENSG00000089154 E018 0.1268540 0.0123038662 3.493182e-01   12 120138857 120138938 82 - 0.000 0.115 12.052
ENSG00000089154 E019 37.4294893 0.0021767428 9.407990e-01 0.9832324738 12 120140859 120141023 165 - 1.577 1.581 0.016
ENSG00000089154 E020 29.0806156 0.0096354697 5.867482e-01 0.8168561910 12 120142507 120142722 216 - 1.456 1.494 0.130
ENSG00000089154 E021 15.3300144 0.0065952754 6.148207e-01 0.8326849259 12 120142824 120142941 118 - 1.190 1.230 0.143
ENSG00000089154 E022 17.0619694 0.0008394725 1.669435e-01 0.4374025754 12 120144306 120144448 143 - 1.289 1.190 -0.350
ENSG00000089154 E023 25.8899344 0.0058488983 8.369425e-01 0.9415686045 12 120144639 120144835 197 - 1.428 1.416 -0.043
ENSG00000089154 E024 14.7337979 0.0082003446 7.441376e-01 0.8987349350 12 120144923 120145061 139 - 1.179 1.207 0.098
ENSG00000089154 E025 8.0083808 0.0017235904 7.619817e-01 0.9071923159 12 120145262 120145330 69 - 0.961 0.932 -0.109
ENSG00000089154 E026 20.9360019 0.0092960836 7.281624e-01 0.8915889315 12 120147052 120147272 221 - 1.323 1.351 0.096
ENSG00000089154 E027 18.0376900 0.0173415302 4.351756e-01 0.7120983016 12 120148167 120148346 180 - 1.242 1.314 0.252
ENSG00000089154 E028 13.1563994 0.0016525461 4.273600e-01 0.7058840454 12 120149606 120149720 115 - 1.118 1.181 0.228
ENSG00000089154 E029 9.5576041 0.0023268600 3.176497e-01 0.6103791145 12 120149922 120150043 122 - 1.054 0.961 -0.341
ENSG00000089154 E030 16.7479890 0.0010281638 6.272429e-01 0.8399454500 12 120151145 120151391 247 - 1.257 1.223 -0.121
ENSG00000089154 E031 19.7926770 0.0006961054 7.816088e-01 0.9160329543 12 120153213 120153407 195 - 1.319 1.301 -0.062
ENSG00000089154 E032 13.9116661 0.0016997596 2.061766e-01 0.4898215509 12 120153744 120153909 166 - 1.206 1.106 -0.358
ENSG00000089154 E033 7.9161747 0.0018581192 5.851660e-01 0.8157445613 12 120154970 120155028 59 - 0.921 0.975 0.202
ENSG00000089154 E034 5.2644801 0.0051068244 1.382187e-01 0.3955791080 12 120155029 120155040 12 - 0.713 0.883 0.672
ENSG00000089154 E035 0.0000000       12 120155041 120155240 200 -      
ENSG00000089154 E036 9.8212889 0.0018381823 6.251014e-01 0.8386201336 12 120155241 120155347 107 - 1.046 1.002 -0.161
ENSG00000089154 E037 8.1430369 0.0113371494 9.297289e-01 0.9793749481 12 120155348 120155430 83 - 0.951 0.961 0.038
ENSG00000089154 E038 11.2773064 0.0323163364 6.126829e-01 0.8315995830 12 120155592 120155719 128 - 1.104 1.052 -0.191
ENSG00000089154 E039 12.1408163 0.0107356768 7.542715e-01 0.9032959311 12 120156461 120156604 144 - 1.124 1.096 -0.102
ENSG00000089154 E040 8.0406367 0.0017351744 6.575464e-01 0.8567451626 12 120156912 120156992 81 - 0.932 0.975 0.164
ENSG00000089154 E041 0.3719033 0.1582104016 3.941180e-01   12 120156993 120157114 122 - 0.079 0.205 1.605
ENSG00000089154 E042 0.2346346 0.0156223751 4.216967e-01   12 120157806 120157848 43 - 0.145 0.000 -13.030
ENSG00000089154 E043 6.4427245 0.0042718885 9.889243e-01 1.0000000000 12 120157849 120157952 104 - 0.866 0.866 -0.003
ENSG00000089154 E044 4.7285532 0.0029859007 6.277078e-01 0.8399859789 12 120157953 120158030 78 - 0.775 0.718 -0.232
ENSG00000089154 E045 3.5096215 0.0040758427 5.664083e-01 0.8046953518 12 120158460 120158478 19 - 0.679 0.604 -0.322
ENSG00000089154 E046 9.2290779 0.0015370017 7.828276e-01 0.9165359723 12 120158479 120158615 137 - 1.014 0.989 -0.092
ENSG00000089154 E047 11.5062282 0.0036297144 2.406156e-01 0.5298471107 12 120159825 120160023 199 - 1.131 1.028 -0.373
ENSG00000089154 E048 10.5447854 0.0307088252 5.509159e-01 0.7949354549 12 120160142 120160255 114 - 1.083 1.015 -0.249
ENSG00000089154 E049 0.1272623 0.0123441688 3.493542e-01   12 120160256 120160303 48 - 0.000 0.115 12.052
ENSG00000089154 E050 0.7437465 0.0138892407 1.873148e-01 0.4653663438 12 120161443 120161489 47 - 0.145 0.344 1.604
ENSG00000089154 E051 8.4664333 0.0313442554 3.547355e-01 0.6444477413 12 120161490 120161583 94 - 1.014 0.900 -0.427
ENSG00000089154 E052 8.4580838 0.0020480571 1.557959e-01 0.4218536942 12 120161880 120162058 179 - 1.022 0.883 -0.521
ENSG00000089154 E053 0.6081146 0.0143394384 9.895746e-01 1.0000000000 12 120162059 120162234 176 - 0.203 0.205 0.019
ENSG00000089154 E054 8.6037868 0.0039607057 4.479848e-01 0.7221475852 12 120162847 120162971 125 - 1.006 0.932 -0.275
ENSG00000089154 E055 0.2536433 0.0160053810 1.294923e-01   12 120162972 120162989 18 - 0.000 0.205 12.991
ENSG00000089154 E056 13.4744797 0.0010225971 6.872908e-01 0.8709670166 12 120163070 120163259 190 - 1.167 1.136 -0.112
ENSG00000089154 E057 7.9385451 0.0017450333 2.973917e-01 0.5905156807 12 120164336 120164495 160 - 0.900 1.002 0.382
ENSG00000089154 E058 2.6843607 0.0088105517 5.928392e-01 0.8205031494 12 120164646 120164670 25 - 0.529 0.604 0.341
ENSG00000089154 E059 4.1338760 0.0064852799 8.649607e-01 0.9533215935 12 120164671 120164721 51 - 0.696 0.718 0.090
ENSG00000089154 E060 7.0846980 0.0055323044 3.076559e-01 0.6008950351 12 120168208 120168300 93 - 0.855 0.961 0.405
ENSG00000089154 E061 3.7214426 0.0102721711 4.043361e-03 0.0427513469 12 120168301 120168495 195 - 0.475 0.847 1.604
ENSG00000089154 E062 7.3849591 0.0018157698 3.734431e-06 0.0001460571 12 120170169 120170321 153 - 1.069 0.533 -2.150
ENSG00000089154 E063 8.1539456 0.0019469581 2.183527e-03 0.0272607329 12 120173653 120173826 174 - 1.061 0.742 -1.217
ENSG00000089154 E064 4.2314600 0.0032930922 3.145220e-01 0.6075509691 12 120174071 120174169 99 - 0.761 0.635 -0.521
ENSG00000089154 E065 3.0523729 0.0116469863 6.734029e-01 0.8647661178 12 120175162 120175212 51 - 0.577 0.635 0.256
ENSG00000089154 E066 4.0359798 0.0882460905 6.140879e-01 0.8322290350 12 120175746 120175789 44 - 0.661 0.743 0.340
ENSG00000089154 E067 5.6199845 0.0260048648 4.772136e-01 0.7435584345 12 120175790 120175874 85 - 0.776 0.866 0.353
ENSG00000089154 E068 5.4670444 0.0032110640 9.693708e-01 0.9936886542 12 120176143 120176217 75 - 0.803 0.808 0.020
ENSG00000089154 E069 7.8394817 0.0017807545 8.092150e-02 0.2923059644 12 120177447 120177555 109 - 1.006 0.828 -0.671
ENSG00000089154 E070 0.0000000       12 120177556 120177683 128 -      
ENSG00000089154 E071 5.5307057 0.0051079955 2.681016e-02 0.1519591234 12 120177684 120177752 69 - 0.900 0.635 -1.065
ENSG00000089154 E072 0.0000000       12 120177753 120177790 38 -      
ENSG00000089154 E073 6.4270307 0.0797469149 7.845354e-01 0.9168385429 12 120178625 120178759 135 - 0.878 0.847 -0.118
ENSG00000089154 E074 3.9920821 0.1961963021 6.674260e-01 0.8615298846 12 120178852 120178889 38 - 0.713 0.665 -0.202
ENSG00000089154 E075 4.9818940 0.2189035965 9.237028e-01 0.9767471341 12 120178890 120178950 61 - 0.760 0.787 0.107
ENSG00000089154 E076 4.4942976 0.0036357140 9.188163e-01 0.9743996150 12 120183569 120183677 109 - 0.730 0.742 0.052
ENSG00000089154 E077 0.2543986 0.0160216868 1.295338e-01   12 120183678 120183721 44 - 0.000 0.205 12.991
ENSG00000089154 E078 5.7228799 0.0028906074 6.962920e-01 0.8760405418 12 120184112 120184243 132 - 0.803 0.847 0.172
ENSG00000089154 E079 3.7561405 0.0038196779 6.315139e-01 0.8419231756 12 120184824 120184887 64 - 0.696 0.635 -0.258
ENSG00000089154 E080 3.1382107 0.0045603000 3.490530e-01 0.6395511153 12 120190298 120190400 103 - 0.660 0.533 -0.565
ENSG00000089154 E081 1.6883271 0.0079074799 3.893373e-01 0.6750594023 12 120194680 120194745 66 - 0.475 0.344 -0.717

Help

Please Click HERE to learn more details about the results from DEXseq.