ENSG00000089280

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000254108 ENSG00000089280 No_inf pgKDN_inf FUS protein_coding protein_coding 374.2654 394.9905 347.4141 2.895757 7.735299 -0.1851567 49.46196 22.23821 62.53981 7.653561 2.7542551 1.4913164 0.13458333 0.056125 0.179825 0.123700 5.663166e-01 6.025416e-07 FALSE  
ENST00000380244 ENSG00000089280 No_inf pgKDN_inf FUS protein_coding protein_coding 374.2654 394.9905 347.4141 2.895757 7.735299 -0.1851567 28.44861 23.37459 32.99610 6.819752 4.2625123 0.4971745 0.07721667 0.059275 0.095875 0.036600 4.733482e-01 6.025416e-07 FALSE  
ENST00000474990 ENSG00000089280 No_inf pgKDN_inf FUS protein_coding protein_coding_CDS_not_defined 374.2654 394.9905 347.4141 2.895757 7.735299 -0.1851567 76.45362 75.13162 67.74170 5.280202 4.1386174 -0.1493552 0.20391667 0.190200 0.194825 0.004625 9.792778e-01 6.025416e-07 FALSE  
ENST00000487509 ENSG00000089280 No_inf pgKDN_inf FUS protein_coding retained_intron 374.2654 394.9905 347.4141 2.895757 7.735299 -0.1851567 23.39439 42.75921 12.19907 1.314714 0.9370734 -1.8086193 0.06125833 0.108300 0.035275 -0.073025 6.025416e-07 6.025416e-07 TRUE  
ENST00000568901 ENSG00000089280 No_inf pgKDN_inf FUS protein_coding retained_intron 374.2654 394.9905 347.4141 2.895757 7.735299 -0.1851567 154.52054 173.95781 145.94876 7.322626 8.8235404 -0.2532596 0.41239167 0.440375 0.419450 -0.020925 8.517260e-01 6.025416e-07    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000089280 E001 0.1268540 1.240674e-02 7.279358e-01   16 31180138 31180138 1 + 0.000 0.083 9.047
ENSG00000089280 E002 0.6170858 2.012882e-02 9.115644e-01 9.717930e-01 16 31180139 31180146 8 + 0.196 0.212 0.146
ENSG00000089280 E003 1.2233726 1.007736e-02 6.367716e-01 8.448988e-01 16 31180147 31180147 1 + 0.385 0.312 -0.439
ENSG00000089280 E004 1.8391651 8.426236e-03 7.475888e-01 9.003446e-01 16 31180148 31180148 1 + 0.476 0.428 -0.247
ENSG00000089280 E005 3.0910208 4.595442e-03 5.140014e-01 7.707877e-01 16 31180149 31180149 1 + 0.552 0.640 0.391
ENSG00000089280 E006 5.3045762 1.158573e-02 7.154300e-01 8.853259e-01 16 31180150 31180150 1 + 0.767 0.811 0.173
ENSG00000089280 E007 52.7571472 1.554174e-03 1.180037e-05 3.943255e-04 16 31180151 31180227 77 + 1.827 1.634 -0.654
ENSG00000089280 E008 42.2362762 1.204119e-03 2.178547e-05 6.623323e-04 16 31182398 31182422 25 + 1.737 1.534 -0.690
ENSG00000089280 E009 0.0000000       16 31182513 31182664 152 +      
ENSG00000089280 E010 6.4977128 3.266653e-03 3.948117e-03 4.205762e-02 16 31182665 31183350 686 + 0.645 0.973 1.298
ENSG00000089280 E011 8.3763131 1.914255e-03 2.308729e-04 4.707712e-03 16 31183550 31183857 308 + 0.698 1.084 1.481
ENSG00000089280 E012 2.2272520 1.431077e-01 5.249182e-01 7.778371e-01 16 31183858 31183860 3 + 0.433 0.547 0.561
ENSG00000089280 E013 93.9602512 1.701328e-04 2.444023e-09 1.944188e-07 16 31183861 31184002 142 + 2.070 1.885 -0.624
ENSG00000089280 E014 86.5869396 1.828468e-04 8.570828e-07 4.065603e-05 16 31184209 31184396 188 + 2.023 1.863 -0.537
ENSG00000089280 E015 0.0000000       16 31184397 31184398 2 +      
ENSG00000089280 E016 0.2448930 1.657777e-02 8.142617e-01   16 31184894 31184938 45 + 0.109 0.083 -0.439
ENSG00000089280 E017 1.3535250 9.947762e-03 8.447163e-01 9.446688e-01 16 31184939 31184939 1 + 0.385 0.354 -0.176
ENSG00000089280 E018 31.3405770 6.916288e-03 4.043160e-02 1.950481e-01 16 31184940 31185079 140 + 1.574 1.446 -0.440
ENSG00000089280 E019 108.0517260 4.885857e-04 3.801219e-11 4.034554e-09 16 31185080 31185179 100 + 2.137 1.938 -0.665
ENSG00000089280 E020 57.8421087 4.408240e-03 9.721725e-11 9.745939e-09 16 31185180 31185498 319 + 1.536 1.869 1.129
ENSG00000089280 E021 17.4671810 7.674755e-04 8.258512e-06 2.898353e-04 16 31185499 31185556 58 + 1.029 1.367 1.201
ENSG00000089280 E022 256.1112785 1.106836e-04 1.317976e-67 4.181396e-64 16 31185557 31186801 1245 + 2.159 2.515 1.188
ENSG00000089280 E023 136.2619643 1.176268e-04 4.474326e-10 4.083220e-08 16 31186802 31186836 35 + 2.218 2.057 -0.538
ENSG00000089280 E024 343.7994224 5.998835e-05 3.822313e-98 2.576908e-94 16 31186837 31188151 1315 + 2.279 2.644 1.218
ENSG00000089280 E025 75.8155201 1.961494e-04 4.969638e-24 1.887552e-21 16 31188152 31188324 173 + 1.609 1.997 1.312
ENSG00000089280 E026 156.1437774 1.545559e-04 9.448647e-08 5.539167e-06 16 31188325 31188357 33 + 2.261 2.131 -0.433
ENSG00000089280 E027 19.8430432 7.294846e-04 1.202635e-06 5.482916e-05 16 31188467 31189119 653 + 1.073 1.422 1.231
ENSG00000089280 E028 3.5742994 4.182408e-02 9.176822e-01 9.740666e-01 16 31189120 31189122 3 + 0.645 0.660 0.063
ENSG00000089280 E029 314.1038671 1.017440e-03 1.200934e-09 1.005764e-07 16 31189123 31189226 104 + 2.560 2.436 -0.415
ENSG00000089280 E030 368.3801655 6.853844e-05 2.351339e-14 3.819793e-12 16 31189665 31189794 130 + 2.625 2.509 -0.388
ENSG00000089280 E031 240.4121208 8.057377e-05 1.950658e-02 1.250081e-01 16 31190040 31190141 102 + 2.402 2.356 -0.152
ENSG00000089280 E032 0.3730368 1.673527e-02 7.885503e-01   16 31190216 31190274 59 + 0.109 0.152 0.561
ENSG00000089280 E033 100.0902289 3.016965e-04 9.685738e-02 3.241394e-01 16 31190275 31190331 57 + 1.966 2.017 0.171
ENSG00000089280 E034 74.6236673 1.998698e-04 2.165434e-01 5.026556e-01 16 31190332 31190372 41 + 1.897 1.852 -0.149
ENSG00000089280 E035 74.6467145 2.296636e-04 4.446060e-02 2.061595e-01 16 31190373 31190398 26 + 1.912 1.841 -0.240
ENSG00000089280 E036 2.5124828 1.480494e-02 1.015840e-02 8.111983e-02 16 31190399 31190741 343 + 0.268 0.660 2.063
ENSG00000089280 E037 129.6367376 1.301966e-04 3.883942e-04 7.121401e-03 16 31190742 31190842 101 + 2.162 2.067 -0.317
ENSG00000089280 E038 100.3917928 1.972303e-04 4.442378e-04 7.959974e-03 16 31190963 31191110 148 + 2.059 1.952 -0.358
ENSG00000089280 E039 102.4452230 1.588447e-04 5.545948e-05 1.454273e-03 16 31191399 31191752 354 + 2.075 1.954 -0.405

Help

Please Click HERE to learn more details about the results from DEXseq.