ENSG00000089351

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000598118 ENSG00000089351 No_inf pgKDN_inf GRAMD1A protein_coding retained_intron 41.02251 35.24357 38.29907 0.3410158 1.01576 0.1199165 1.391199 2.361185 0.4215622 0.2309016 0.1792169 -2.4579678 0.0353750 0.067125 0.011175 -0.05595 0.0771237497 0.0004518071 FALSE TRUE
ENST00000680623 ENSG00000089351 No_inf pgKDN_inf GRAMD1A protein_coding protein_coding 41.02251 35.24357 38.29907 0.3410158 1.01576 0.1199165 31.741156 21.935658 33.6035531 1.6832262 0.8883973 0.6151075 0.7674833 0.623850 0.877700 0.25385 0.0004518071 0.0004518071 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000089351 E001 0.0000000       19 34994784 34994825 42 +      
ENSG00000089351 E002 0.0000000       19 34995994 34996291 298 +      
ENSG00000089351 E003 0.0000000       19 34999387 34999436 50 +      
ENSG00000089351 E004 7.1270791 0.0019805821 2.649836e-02 0.1508192082 19 35000323 35000371 49 + 1.004 0.778 -0.864
ENSG00000089351 E005 8.9663026 0.0015546089 8.292638e-02 0.2967653895 19 35000372 35000425 54 + 1.068 0.909 -0.589
ENSG00000089351 E006 7.3844960 0.0018939694 5.746769e-02 0.2397109514 19 35000426 35000455 30 + 1.004 0.815 -0.719
ENSG00000089351 E007 5.9493131 0.1056826013 3.851324e-01 0.6712126103 19 35000456 35000486 31 + 0.894 0.778 -0.449
ENSG00000089351 E008 0.2542726 0.2381301400 2.467465e-01   19 35001140 35001244 105 + 0.000 0.184 12.273
ENSG00000089351 E009 0.5079806 0.0589111617 3.615204e-02 0.1825604577 19 35002422 35002543 122 + 0.000 0.312 13.273
ENSG00000089351 E010 0.1186381 0.0117786696 6.174496e-01   19 35002745 35002825 81 + 0.089 0.000 -10.958
ENSG00000089351 E011 0.4990093 0.0200828915 2.585182e-01   19 35005747 35005931 185 + 0.089 0.253 1.795
ENSG00000089351 E012 23.5262857 0.0032156431 5.108943e-01 0.7682643865 19 35009119 35009329 211 + 1.408 1.369 -0.135
ENSG00000089351 E013 7.9280541 0.0074170714 7.670482e-01 0.9097500946 19 35009423 35009443 21 + 0.963 0.936 -0.102
ENSG00000089351 E014 0.0000000       19 35009444 35009445 2 +      
ENSG00000089351 E015 0.1272623 0.0122765836 4.681985e-01   19 35009673 35009887 215 + 0.000 0.101 11.273
ENSG00000089351 E016 20.0691557 0.0059989249 2.105200e-01 0.4949946115 19 35009888 35009972 85 + 1.363 1.277 -0.302
ENSG00000089351 E017 25.1263444 0.0005706204 1.462219e-02 0.1032466619 19 35010092 35010195 104 + 1.479 1.338 -0.486
ENSG00000089351 E018 24.5563397 0.0005833050 9.407753e-01 0.9832324738 19 35010284 35010379 96 + 1.408 1.406 -0.005
ENSG00000089351 E019 3.8256669 0.0040712882 1.035232e-01 0.3362873418 19 35010380 35010639 260 + 0.572 0.778 0.873
ENSG00000089351 E020 12.0723471 0.0011859856 3.621293e-02 0.1827555186 19 35011474 35011483 10 + 1.024 1.197 0.625
ENSG00000089351 E021 18.6396146 0.0007314423 2.366058e-01 0.5255364868 19 35011484 35011554 71 + 1.251 1.333 0.286
ENSG00000089351 E022 1.9828528 0.1494254626 1.902756e-01 0.4693163371 19 35012988 35013255 268 + 0.330 0.591 1.348
ENSG00000089351 E023 22.9324205 0.0006260471 6.096752e-01 0.8301746289 19 35013256 35013368 113 + 1.392 1.364 -0.098
ENSG00000089351 E024 0.8692483 0.0125110980 1.864345e-01 0.4643986466 19 35013369 35013540 172 + 0.163 0.365 1.532
ENSG00000089351 E025 16.9128081 0.0161985399 4.406528e-01 0.7163478814 19 35013541 35013606 66 + 1.217 1.289 0.253
ENSG00000089351 E026 22.9184629 0.0087042405 3.305878e-01 0.6231188492 19 35013607 35013691 85 + 1.341 1.415 0.257
ENSG00000089351 E027 36.7365352 0.0003871964 7.201215e-01 0.8872665655 19 35014189 35014387 199 + 1.583 1.569 -0.049
ENSG00000089351 E028 2.3963696 0.2575027727 1.137562e-02 0.0875618388 19 35014388 35014879 492 + 0.163 0.739 3.297
ENSG00000089351 E029 4.2666226 0.0048723041 2.130246e-05 0.0006484661 19 35014969 35015823 855 + 0.374 0.923 2.433
ENSG00000089351 E030 25.6228035 0.0006915620 1.351389e-01 0.3908440418 19 35015824 35015967 144 + 1.380 1.469 0.307
ENSG00000089351 E031 28.1742514 0.0005798109 2.882461e-01 0.5818531389 19 35019191 35019309 119 + 1.434 1.495 0.210
ENSG00000089351 E032 29.1634317 0.0005153796 1.795350e-01 0.4547308721 19 35019391 35019533 143 + 1.441 1.517 0.259
ENSG00000089351 E033 29.2476428 0.0004745003 5.302893e-01 0.7814378486 19 35021502 35021605 104 + 1.462 1.499 0.126
ENSG00000089351 E034 53.4561868 0.0006333705 5.738099e-01 0.8090198249 19 35021691 35021864 174 + 1.745 1.725 -0.067
ENSG00000089351 E035 38.4186917 0.0003638149 1.534675e-02 0.1068015303 19 35021951 35022038 88 + 1.646 1.534 -0.382
ENSG00000089351 E036 1.3769406 0.0181268033 1.803476e-02 0.1185015651 19 35022900 35022911 12 + 0.163 0.528 2.380
ENSG00000089351 E037 34.9232010 0.0004861904 8.041435e-01 0.9272786476 19 35023236 35023297 62 + 1.560 1.550 -0.032
ENSG00000089351 E038 31.3297489 0.0005257150 3.385606e-01 0.6302707394 19 35023298 35023343 46 + 1.531 1.484 -0.162
ENSG00000089351 E039 39.4895455 0.0003496574 2.681909e-01 0.5616886587 19 35023427 35023547 121 + 1.630 1.581 -0.166
ENSG00000089351 E040 2.3489668 0.0103628805 1.540207e-01 0.4190986814 19 35023548 35023830 283 + 0.414 0.619 0.988
ENSG00000089351 E041 61.6283418 0.0003624578 6.112021e-01 0.8308704974 19 35026049 35026471 423 + 1.786 1.807 0.073

Help

Please Click HERE to learn more details about the results from DEXseq.