ENSG00000090238

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000398838 ENSG00000090238 No_inf pgKDN_inf YPEL3 protein_coding protein_coding 59.80514 109.7633 36.21171 4.0677 2.83896 -1.5996 37.850747 66.50447 26.754358 2.596922 2.8953188 -1.313355 0.65799167 0.606850 0.736925 0.130075 2.876458e-01 4.745025e-11 FALSE FALSE
ENST00000398841 ENSG00000090238 No_inf pgKDN_inf YPEL3 protein_coding protein_coding 59.80514 109.7633 36.21171 4.0677 2.83896 -1.5996 5.289917 11.01340 2.000685 1.028722 0.3032701 -2.454810 0.08357500 0.101675 0.057725 -0.043950 5.361992e-01 4.745025e-11 FALSE FALSE
ENST00000565479 ENSG00000090238 No_inf pgKDN_inf YPEL3 protein_coding protein_coding_CDS_not_defined 59.80514 109.7633 36.21171 4.0677 2.83896 -1.5996 4.681589 7.11871 2.213203 1.606142 1.5233195 -1.681002 0.08870833 0.064425 0.072550 0.008125 8.175674e-01 4.745025e-11 FALSE FALSE
ENST00000568674 ENSG00000090238 No_inf pgKDN_inf YPEL3 protein_coding protein_coding_CDS_not_defined 59.80514 109.7633 36.21171 4.0677 2.83896 -1.5996 2.111535 0.00000 4.238481 0.000000 2.7639908 8.730803 0.05245000 0.000000 0.103225 0.103225 2.349955e-01 4.745025e-11 FALSE FALSE
ENST00000570099 ENSG00000090238 No_inf pgKDN_inf YPEL3 protein_coding nonsense_mediated_decay 59.80514 109.7633 36.21171 4.0677 2.83896 -1.5996 7.150257 19.13407 0.000000 4.315568 0.0000000 -10.902682 0.07763333 0.173075 0.000000 -0.173075 4.745025e-11 4.745025e-11   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000090238 E001 3.0205943 0.0049750545 0.2405640845 0.529812705 16 30092314 30092339 26 - 0.377 0.571 0.979
ENSG00000090238 E002 4.1524883 0.0037837485 0.1503917428 0.412977205 16 30092340 30092348 9 - 0.454 0.678 1.029
ENSG00000090238 E003 70.6657413 0.0002358913 0.0445822105 0.206358305 16 30092349 30092576 228 - 1.694 1.783 0.299
ENSG00000090238 E004 42.2392073 0.0009101900 0.8828381893 0.960560720 16 30092577 30092636 60 - 1.551 1.546 -0.019
ENSG00000090238 E005 74.1091169 0.0002347372 0.1404096177 0.398742989 16 30092637 30092760 124 - 1.829 1.774 -0.185
ENSG00000090238 E006 36.1653511 0.0003907917 0.2179028909 0.504290785 16 30092761 30092777 17 - 1.534 1.467 -0.231
ENSG00000090238 E007 37.3453570 0.0014864713 0.6138896200 0.832127542 16 30092778 30092799 22 - 1.516 1.490 -0.092
ENSG00000090238 E008 0.2543986 0.0159678760 1.0000000000   16 30093745 30093761 17 - 0.000 0.100 9.225
ENSG00000090238 E009 2.0347505 0.2324348239 0.0506619621 0.222508328 16 30093762 30093934 173 - 0.000 0.489 11.546
ENSG00000090238 E010 4.0538929 0.0069809796 0.0024570414 0.029725902 16 30093935 30094110 176 - 0.165 0.701 3.125
ENSG00000090238 E011 3.7722407 0.0037366548 0.2338547478 0.522850473 16 30094111 30094384 274 - 0.454 0.641 0.872
ENSG00000090238 E012 2.4038904 0.0194623644 0.0492124992 0.218726897 16 30094385 30094475 91 - 0.165 0.523 2.341
ENSG00000090238 E013 5.5505761 0.0026232798 0.0246555356 0.144289459 16 30094476 30094788 313 - 0.454 0.792 1.493
ENSG00000090238 E014 48.5589712 0.0049708376 0.3593555609 0.648785467 16 30094789 30094852 64 - 1.642 1.596 -0.158
ENSG00000090238 E015 38.7807489 0.0004297722 0.1650262402 0.434553522 16 30094853 30094897 45 - 1.568 1.495 -0.250
ENSG00000090238 E016 2.3838429 0.0131334942 0.5138735825 0.770660340 16 30094898 30094930 33 - 0.377 0.488 0.586
ENSG00000090238 E017 3.1373770 0.0048669590 0.4649425685 0.734270442 16 30094931 30094997 67 - 0.454 0.571 0.563
ENSG00000090238 E018 3.0007658 0.0083273459 0.9048054179 0.969526507 16 30094998 30095102 105 - 0.519 0.540 0.097
ENSG00000090238 E019 32.6010389 0.0004196527 0.0195870013 0.125364513 16 30095103 30095146 44 - 1.540 1.407 -0.456
ENSG00000090238 E020 46.5456864 0.0003782747 0.4086121361 0.690870778 16 30095252 30095335 84 - 1.619 1.580 -0.133
ENSG00000090238 E021 32.3728413 0.0041209731 0.6916953424 0.873674393 16 30095336 30095434 99 - 1.413 1.441 0.096
ENSG00000090238 E022 28.0552170 0.0005484852 0.0002797618 0.005486791 16 30095435 30095977 543 - 1.144 1.420 0.971
ENSG00000090238 E023 3.1446439 0.0530610003 0.2462662903 0.536955292 16 30095978 30095995 18 - 0.377 0.586 1.045
ENSG00000090238 E024 3.7534497 0.0789914090 0.8588273814 0.950836416 16 30095996 30096096 101 - 0.576 0.614 0.170
ENSG00000090238 E025 29.8086730 0.0004896171 0.2892898547 0.582943668 16 30096097 30096255 159 - 1.451 1.387 -0.220
ENSG00000090238 E026 0.0000000       16 30096616 30096744 129 -      
ENSG00000090238 E027 0.0000000       16 30096745 30096915 171 -      

Help

Please Click HERE to learn more details about the results from DEXseq.