ENSG00000090316

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303400 ENSG00000090316 No_inf pgKDN_inf MAEA protein_coding protein_coding 44.32322 37.52384 49.22779 1.311671 1.527504 0.3915743 36.861477 28.355373 44.36611 1.9659953 1.40877276 0.6456524 0.8237417 0.752925 0.901225 0.1483 0.001674929 0.001674929 FALSE TRUE
ENST00000515766 ENSG00000090316 No_inf pgKDN_inf MAEA protein_coding retained_intron 44.32322 37.52384 49.22779 1.311671 1.527504 0.3915743 2.663511 4.282435 1.30498 0.5596642 0.09675129 -1.7067553 0.0643500 0.114125 0.026625 -0.0875 0.025780396 0.001674929 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000090316 E001 0.6073281 1.483298e-02 7.529622e-01 9.027349e-01 4 1289887 1289889 3 + 0.227 0.183 -0.392
ENSG00000090316 E002 0.6073281 1.483298e-02 7.529622e-01 9.027349e-01 4 1289890 1289890 1 + 0.227 0.183 -0.392
ENSG00000090316 E003 0.7249587 1.425762e-02 4.995671e-01 7.597894e-01 4 1289891 1289893 3 + 0.282 0.183 -0.807
ENSG00000090316 E004 0.9705158 1.363734e-02 5.903339e-01 8.186857e-01 4 1289894 1289894 1 + 0.331 0.252 -0.544
ENSG00000090316 E005 0.9705158 1.363734e-02 5.903339e-01 8.186857e-01 4 1289895 1289896 2 + 0.331 0.252 -0.544
ENSG00000090316 E006 1.9230643 1.298090e-02 7.580660e-02 2.813392e-01 4 1289897 1289907 11 + 0.574 0.311 -1.392
ENSG00000090316 E007 1.9230643 1.298090e-02 7.580660e-02 2.813392e-01 4 1289908 1289913 6 + 0.574 0.311 -1.392
ENSG00000090316 E008 12.5298069 1.196392e-03 2.019332e-01 4.843056e-01 4 1289914 1289982 69 + 1.175 1.079 -0.345
ENSG00000090316 E009 0.1271363 1.232135e-02 4.782509e-01   4 1297956 1298069 114 + 0.000 0.101 11.168
ENSG00000090316 E010 0.1271363 1.232135e-02 4.782509e-01   4 1298070 1298115 46 + 0.000 0.101 11.168
ENSG00000090316 E011 0.2442663 1.618018e-02 9.270522e-01   4 1299530 1299969 440 + 0.090 0.101 0.193
ENSG00000090316 E012 0.0000000       4 1309443 1309466 24 +      
ENSG00000090316 E013 0.0000000       4 1309467 1309595 129 +      
ENSG00000090316 E014 0.0000000       4 1309596 1309712 117 +      
ENSG00000090316 E015 0.0000000       4 1309787 1309996 210 +      
ENSG00000090316 E016 37.1019889 4.031932e-04 4.103472e-01 6.921553e-01 4 1311979 1312161 183 + 1.596 1.563 -0.111
ENSG00000090316 E017 0.0000000       4 1312162 1312238 77 +      
ENSG00000090316 E018 0.0000000       4 1312239 1312586 348 +      
ENSG00000090316 E019 47.8032523 2.961143e-04 1.945397e-01 4.744643e-01 4 1315397 1315600 204 + 1.711 1.663 -0.162
ENSG00000090316 E020 41.6887590 2.684682e-03 2.626424e-01 5.554442e-01 4 1322381 1322503 123 + 1.653 1.605 -0.163
ENSG00000090316 E021 0.3813786 3.279156e-02 8.428676e-02   4 1323495 1323608 114 + 0.000 0.252 12.571
ENSG00000090316 E022 29.8595868 5.471319e-04 2.832081e-01 5.768550e-01 4 1327627 1327703 77 + 1.513 1.462 -0.174
ENSG00000090316 E023 1.8589901 7.544502e-03 1.306035e-01 3.833453e-01 4 1328634 1329056 423 + 0.331 0.558 1.193
ENSG00000090316 E024 0.9974567 1.232854e-01 1.582937e-01 4.251911e-01 4 1329057 1329343 287 + 0.164 0.410 1.779
ENSG00000090316 E025 2.3949477 6.126043e-02 5.086777e-04 8.855722e-03 4 1329344 1330003 660 + 0.164 0.736 3.281
ENSG00000090316 E026 5.9952567 7.384178e-03 4.040266e-05 1.110469e-03 4 1330004 1332166 2163 + 0.546 1.029 1.943
ENSG00000090316 E027 1.2614526 1.370845e-01 1.335267e-02 9.698581e-02 4 1332167 1332560 394 + 0.089 0.526 3.364
ENSG00000090316 E028 1.3870756 9.822944e-03 2.170187e-03 2.713815e-02 4 1332561 1332756 196 + 0.090 0.558 3.515
ENSG00000090316 E029 33.8617034 3.946774e-04 1.168793e-01 3.607759e-01 4 1332757 1332865 109 + 1.575 1.504 -0.246
ENSG00000090316 E030 38.7873327 3.853018e-04 2.699445e-01 5.635668e-01 4 1336861 1336994 134 + 1.621 1.576 -0.153
ENSG00000090316 E031 25.2151549 1.029064e-02 2.024340e-13 2.865637e-11 4 1336995 1338421 1427 + 1.062 1.621 1.955
ENSG00000090316 E032 13.6259825 5.152014e-03 1.684883e-01 4.397839e-01 4 1338422 1338425 4 + 1.213 1.106 -0.381
ENSG00000090316 E033 44.5964039 5.868671e-03 1.795973e-01 4.548193e-01 4 1338426 1338617 192 + 1.689 1.624 -0.220
ENSG00000090316 E034 4.9695233 2.545385e-02 8.937807e-03 7.459791e-02 4 1338618 1339073 456 + 0.574 0.921 1.416
ENSG00000090316 E035 231.3959695 9.443268e-05 5.944044e-01 8.216153e-01 4 1339074 1340147 1074 + 2.367 2.365 -0.005

Help

Please Click HERE to learn more details about the results from DEXseq.