ENSG00000090339

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264832 ENSG00000090339 No_inf pgKDN_inf ICAM1 protein_coding protein_coding 212.984 39.50009 271.4766 0.6812011 2.556006 2.780588 134.15778 19.40992 172.6492 0.6418556 1.668910 3.152318 0.5898500 0.491700 0.636250 0.14455 0.005077245 0.005077245 FALSE TRUE
ENST00000423829 ENSG00000090339 No_inf pgKDN_inf ICAM1 protein_coding protein_coding 212.984 39.50009 271.4766 0.6812011 2.556006 2.780588 76.36831 18.75385 95.4162 0.8543958 4.216647 2.346430 0.3919167 0.474225 0.351125 -0.12310 0.049613612 0.005077245 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000090339 E001 0.5882882 1.563342e-01 0.914612178 0.97309389 19 10271093 10271119 27 + 0.171 0.001 -8.331
ENSG00000090339 E002 21.8803872 9.271414e-04 0.282342744 0.57601806 19 10271120 10271226 107 + 1.226 1.127 -0.353
ENSG00000090339 E003 108.9801583 1.460391e-04 0.019961658 0.12688718 19 10274765 10275028 264 + 1.902 1.804 -0.330
ENSG00000090339 E004 1.2151255 1.027120e-02 0.039687851 0.19305782 19 10282258 10282342 85 + 0.199 0.542 2.098
ENSG00000090339 E005 3.1488569 5.337885e-03 0.006933032 0.06270772 19 10283112 10283281 170 + 0.422 0.818 1.765
ENSG00000090339 E006 3.5073295 1.882252e-02 0.005861166 0.05551741 19 10283282 10283480 199 + 0.453 0.857 1.757
ENSG00000090339 E007 29.2722334 5.085622e-04 0.317315739 0.61008374 19 10283481 10283494 14 + 1.344 1.264 -0.278
ENSG00000090339 E008 53.5553959 3.777489e-04 0.212382286 0.49760306 19 10283495 10283557 63 + 1.596 1.522 -0.253
ENSG00000090339 E009 140.6491373 1.314699e-04 0.006869289 0.06227740 19 10283558 10283786 229 + 2.011 1.912 -0.334
ENSG00000090339 E010 74.1336367 2.246248e-04 0.905912360 0.97000331 19 10284033 10284128 96 + 1.725 1.720 -0.016
ENSG00000090339 E011 128.3047852 2.949105e-03 0.535073372 0.78488488 19 10284129 10284320 192 + 1.955 1.982 0.090
ENSG00000090339 E012 170.2232602 1.362418e-04 0.498592370 0.75899394 19 10284403 10284657 255 + 2.077 2.099 0.074
ENSG00000090339 E013 109.0166355 2.848762e-04 0.874127233 0.95698783 19 10284783 10285028 246 + 1.888 1.895 0.025
ENSG00000090339 E014 558.3839029 8.681755e-05 0.026429167 0.15067702 19 10285115 10286615 1501 + 2.589 2.622 0.109

Help

Please Click HERE to learn more details about the results from DEXseq.