ENSG00000090376

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261233 ENSG00000090376 No_inf pgKDN_inf IRAK3 protein_coding protein_coding 12.20329 18.86347 6.696327 1.08646 0.4155696 -1.492765 2.5131214 1.233244 4.5729120 0.7362320 0.2425674 1.8821555 0.30306667 0.062375 0.687475 0.625100 1.734301e-03 5.280042e-06 FALSE TRUE
ENST00000545837 ENSG00000090376 No_inf pgKDN_inf IRAK3 protein_coding protein_coding 12.20329 18.86347 6.696327 1.08646 0.4155696 -1.492765 0.9296441 1.118832 0.7990412 0.1994153 0.1346315 -0.4805453 0.08919167 0.059575 0.117800 0.058225 6.540994e-01 5.280042e-06 FALSE FALSE
ENST00000617296 ENSG00000090376 No_inf pgKDN_inf IRAK3 protein_coding miRNA 12.20329 18.86347 6.696327 1.08646 0.4155696 -1.492765 2.7414773 5.383420 0.5846984 0.4274137 0.5846984 -3.1809703 0.17445833 0.288975 0.075100 -0.213875 1.468811e-01 5.280042e-06   FALSE
MSTRG.6778.4 ENSG00000090376 No_inf pgKDN_inf IRAK3 protein_coding   12.20329 18.86347 6.696327 1.08646 0.4155696 -1.492765 1.1893786 1.960411 0.0000000 1.1322264 0.0000000 -7.6223528 0.06880000 0.096475 0.000000 -0.096475 7.000467e-01 5.280042e-06   FALSE
MSTRG.6778.5 ENSG00000090376 No_inf pgKDN_inf IRAK3 protein_coding   12.20329 18.86347 6.696327 1.08646 0.4155696 -1.492765 2.7555137 5.890323 0.0000000 0.6063614 0.0000000 -9.2046500 0.20686667 0.317825 0.000000 -0.317825 5.280042e-06 5.280042e-06 FALSE TRUE
MSTRG.6778.6 ENSG00000090376 No_inf pgKDN_inf IRAK3 protein_coding   12.20329 18.86347 6.696327 1.08646 0.4155696 -1.492765 1.4531712 3.277239 0.7396758 0.2050166 0.2924434 -2.1325379 0.10924167 0.174775 0.119650 -0.055125 8.100521e-01 5.280042e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000090376 E001 0.2444846 0.0163853494 4.949639e-01   12 66189195 66189213 19 + 0.140 0.063 -1.273
ENSG00000090376 E002 0.8615704 0.0169107827 4.590744e-01 7.307848e-01 12 66189214 66189256 43 + 0.331 0.212 -0.858
ENSG00000090376 E003 2.5405548 0.0061283389 5.067831e-04 8.836704e-03 12 66189257 66189432 176 + 0.801 0.323 -2.273
ENSG00000090376 E004 0.7524964 0.0143513004 4.889291e-01 7.520214e-01 12 66194088 66194204 117 + 0.140 0.252 1.049
ENSG00000090376 E005 5.7942082 0.0024746315 1.109019e-01 3.495839e-01 12 66196880 66198078 1199 + 0.915 0.733 -0.714
ENSG00000090376 E006 0.8695655 0.0131678101 9.589314e-01 9.903220e-01 12 66198079 66198136 58 + 0.246 0.252 0.049
ENSG00000090376 E007 0.3639133 0.1974791624 2.249855e-01   12 66198137 66198220 84 + 0.246 0.063 -2.274
ENSG00000090376 E008 6.9283036 0.0019939289 3.147535e-01 6.076605e-01 12 66203711 66203893 183 + 0.935 0.824 -0.425
ENSG00000090376 E009 0.5087973 0.0469705498 2.602558e-01 5.529158e-01 12 66208236 66208269 34 + 0.000 0.212 10.375
ENSG00000090376 E010 4.6658002 0.0957505273 1.268771e-01 3.775650e-01 12 66209456 66209520 65 + 0.873 0.634 -0.969
ENSG00000090376 E011 4.1673515 0.1594222057 1.261604e-01 3.766312e-01 12 66210147 66210201 55 + 0.850 0.583 -1.104
ENSG00000090376 E012 7.7189589 0.0018654149 1.051886e-03 1.557300e-02 12 66211446 66211597 152 + 1.107 0.781 -1.227
ENSG00000090376 E013 4.4670484 0.0032650656 8.864366e-01 9.620112e-01 12 66217171 66217235 65 + 0.715 0.693 -0.089
ENSG00000090376 E014 4.8052452 0.0029398324 1.267948e-01 3.774563e-01 12 66226723 66226837 115 + 0.851 0.665 -0.750
ENSG00000090376 E015 5.2694173 0.0026850673 8.052400e-03 6.943215e-02 12 66228252 66228370 119 + 0.954 0.650 -1.206
ENSG00000090376 E016 2.7304678 0.0057190231 8.111487e-01 9.305245e-01 12 66244241 66244407 167 + 0.564 0.527 -0.174
ENSG00000090376 E017 6.2032515 0.0260138877 7.193411e-01 8.868075e-01 12 66244486 66244562 77 + 0.850 0.803 -0.185
ENSG00000090376 E018 8.7667918 0.0465638051 1.473640e-01 4.086760e-01 12 66244563 66244684 122 + 1.067 0.890 -0.654
ENSG00000090376 E019 4.9212422 0.0034531165 3.968298e-02 1.930578e-01 12 66244948 66245010 63 + 0.895 0.650 -0.984
ENSG00000090376 E020 12.1684324 0.0115943613 8.184724e-01 9.339397e-01 12 66245098 66245262 165 + 1.094 1.068 -0.092
ENSG00000090376 E021 0.2541163 0.0161143687 7.472926e-01   12 66246590 66246620 31 + 0.000 0.119 9.546
ENSG00000090376 E022 147.8514484 0.0001294295 6.680559e-01 8.618602e-01 12 66247695 66251081 3387 + 2.135 2.122 -0.045
ENSG00000090376 E023 182.7836592 0.0001371291 9.497917e-09 6.793908e-07 12 66251082 66254622 3541 + 2.135 2.245 0.366

Help

Please Click HERE to learn more details about the results from DEXseq.