ENSG00000090861

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261772 ENSG00000090861 No_inf pgKDN_inf AARS1 protein_coding protein_coding 32.6219 23.14563 35.97497 0.396814 0.6940998 0.6360314 26.76481 16.437233 32.1799594 1.2408065 1.0316601 0.9687659 0.8068583 0.70915 0.894050 0.184900 0.02207382 0.02207382 FALSE TRUE
ENST00000674962 ENSG00000090861 No_inf pgKDN_inf AARS1 protein_coding retained_intron 32.6219 23.14563 35.97497 0.396814 0.6940998 0.6360314 1.12655 1.855867 0.3526332 0.2141983 0.2127443 -2.3632629 0.0403000 0.08065 0.010075 -0.070575 0.04310154 0.02207382 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000090861 E001 0.2459655 0.0161599567 8.157844e-01   16 70251983 70252027 45 - 0.083 0.109 0.438
ENSG00000090861 E002 0.8707291 0.0124658122 1.262940e-01 3.767654e-01 16 70252028 70252269 242 - 0.152 0.385 1.760
ENSG00000090861 E003 0.4778660 0.5003603693 7.400666e-01   16 70252270 70252297 28 - 0.212 0.109 -1.144
ENSG00000090861 E004 0.8588976 0.2499913320 4.639728e-01 7.336238e-01 16 70252298 70252302 5 - 0.212 0.330 0.855
ENSG00000090861 E005 0.7418937 0.0407329988 2.484211e-01 5.392772e-01 16 70252303 70252304 2 - 0.152 0.330 1.438
ENSG00000090861 E006 0.9792349 0.0120570525 6.756362e-01 8.656554e-01 16 70252305 70252306 2 - 0.265 0.330 0.438
ENSG00000090861 E007 1.1063712 0.0109536546 4.386768e-01 7.147265e-01 16 70252307 70252309 3 - 0.265 0.385 0.760
ENSG00000090861 E008 97.9106538 0.0015672841 3.377798e-01 6.295784e-01 16 70252310 70252906 597 - 1.978 2.010 0.110
ENSG00000090861 E009 26.1840970 0.0006041234 7.481386e-02 2.790464e-01 16 70253268 70253381 114 - 1.383 1.486 0.357
ENSG00000090861 E010 1.8497668 0.0083164681 1.807511e-01 4.564607e-01 16 70253382 70253665 284 - 0.354 0.552 1.023
ENSG00000090861 E011 1.1092613 0.0114252713 4.379820e-01 7.141808e-01 16 70253666 70253713 48 - 0.265 0.385 0.760
ENSG00000090861 E012 31.6157256 0.0050416939 4.433689e-01 7.182593e-01 16 70253714 70253800 87 - 1.489 1.536 0.159
ENSG00000090861 E013 34.5261309 0.0112579760 5.370410e-01 7.861462e-01 16 70253919 70254038 120 - 1.529 1.570 0.141
ENSG00000090861 E014 0.6080157 0.0189234327 9.092101e-01 9.712095e-01 16 70254039 70254268 230 - 0.212 0.196 -0.147
ENSG00000090861 E015 0.0000000       16 70254269 70254390 122 -      
ENSG00000090861 E016 0.0000000       16 70254391 70254483 93 -      
ENSG00000090861 E017 0.2362687 0.0156241656 3.634324e-01   16 70254484 70254620 137 - 0.152 0.000 -13.889
ENSG00000090861 E018 33.9243722 0.0004269817 4.138641e-01 6.943741e-01 16 70254621 70254734 114 - 1.521 1.564 0.147
ENSG00000090861 E019 1.7405426 0.0089218633 3.132290e-02 1.670493e-01 16 70254735 70255185 451 - 0.265 0.585 1.760
ENSG00000090861 E020 0.4712842 0.0404022358 9.181580e-02   16 70255442 70255719 278 - 0.265 0.000 -14.687
ENSG00000090861 E021 0.2454921 0.0163105628 8.154214e-01   16 70255720 70255727 8 - 0.083 0.109 0.438
ENSG00000090861 E022 27.6316614 0.0005128055 8.296693e-01 9.382722e-01 16 70255728 70255836 109 - 1.459 1.448 -0.036
ENSG00000090861 E023 16.3742861 0.0051067024 1.001164e-14 1.666568e-12 16 70255837 70258032 2196 - 0.851 1.478 2.253
ENSG00000090861 E024 10.9428377 0.0015602668 7.832028e-01 9.165837e-01 16 70258033 70258052 20 - 1.084 1.062 -0.080
ENSG00000090861 E025 28.3982720 0.0006788963 9.437449e-02 3.197387e-01 16 70258053 70258217 165 - 1.504 1.411 -0.319
ENSG00000090861 E026 0.3642603 0.2192001785 8.260495e-01   16 70258218 70258244 27 - 0.153 0.109 -0.563
ENSG00000090861 E027 0.8545807 0.0128631851 9.869084e-01 9.995478e-01 16 70258245 70258979 735 - 0.265 0.268 0.023
ENSG00000090861 E028 16.7799372 0.0021584289 5.308224e-01 7.816468e-01 16 70258980 70259023 44 - 1.266 1.222 -0.156
ENSG00000090861 E029 13.1221593 0.0111343444 4.986682e-01 7.590858e-01 16 70259024 70259035 12 - 1.173 1.113 -0.214
ENSG00000090861 E030 37.9245522 0.0004261954 2.583164e-01 5.506679e-01 16 70259036 70259186 151 - 1.610 1.557 -0.182
ENSG00000090861 E031 31.8751139 0.0093202843 5.416515e-01 7.892699e-01 16 70261044 70261150 107 - 1.532 1.490 -0.143
ENSG00000090861 E032 12.2833612 0.0200734489 6.320093e-01 8.422447e-01 16 70261151 70261157 7 - 1.141 1.093 -0.171
ENSG00000090861 E033 0.1271363 0.0123632560 3.961007e-01   16 70261158 70261413 256 - 0.000 0.109 12.695
ENSG00000090861 E034 16.6914086 0.0134671453 9.783862e-01 9.970446e-01 16 70262346 70262366 21 - 1.246 1.244 -0.008
ENSG00000090861 E035 13.9025942 0.0099071235 7.856653e-01 9.174779e-01 16 70262367 70262372 6 - 1.160 1.183 0.082
ENSG00000090861 E036 33.3934331 0.0043145591 7.748766e-01 9.135318e-01 16 70262373 70262472 100 - 1.526 1.543 0.057
ENSG00000090861 E037 15.1831854 0.0011201057 4.504848e-01 7.237763e-01 16 70262473 70262484 12 - 1.230 1.175 -0.195
ENSG00000090861 E038 17.6433398 0.0007929272 7.753031e-01 9.136938e-01 16 70262485 70262524 40 - 1.276 1.258 -0.064
ENSG00000090861 E039 0.4898235 0.0161256420 7.664113e-01   16 70264804 70264957 154 - 0.152 0.196 0.438
ENSG00000090861 E040 30.0688035 0.0005396004 7.859739e-01 9.175281e-01 16 70264958 70265102 145 - 1.495 1.482 -0.045
ENSG00000090861 E041 0.0000000       16 70265103 70265515 413 -      
ENSG00000090861 E042 22.1773615 0.0006204505 9.335301e-01 9.808411e-01 16 70265538 70265662 125 - 1.359 1.366 0.023
ENSG00000090861 E043 27.6558532 0.0005062477 8.502968e-01 9.469821e-01 16 70267659 70267809 151 - 1.449 1.461 0.042
ENSG00000090861 E044 19.8938176 0.0022034822 1.731488e-01 4.462468e-01 16 70268271 70268379 109 - 1.355 1.264 -0.318
ENSG00000090861 E045 0.0000000       16 70268380 70268395 16 -      
ENSG00000090861 E046 25.9892942 0.0102337329 2.844671e-01 5.782052e-01 16 70269618 70269763 146 - 1.459 1.387 -0.249
ENSG00000090861 E047 0.2537694 0.0159676891 1.557560e-01   16 70269764 70269834 71 - 0.000 0.196 13.630
ENSG00000090861 E048 22.3691176 0.0006899373 5.203297e-01 7.747076e-01 16 70270196 70270340 145 - 1.383 1.344 -0.134
ENSG00000090861 E049 19.6330271 0.0137482073 7.209751e-01 8.876249e-01 16 70271781 70271888 108 - 1.299 1.327 0.096
ENSG00000090861 E050 21.3454855 0.0028443029 6.015326e-01 8.257521e-01 16 70271889 70271972 84 - 1.330 1.366 0.124
ENSG00000090861 E051 20.8293466 0.0102192504 8.622354e-01 9.524393e-01 16 70276486 70276631 146 - 1.330 1.344 0.048
ENSG00000090861 E052 25.8399867 0.0048061911 1.761834e-01 4.503235e-01 16 70276966 70277154 189 - 1.462 1.376 -0.295
ENSG00000090861 E053 0.2340080 0.2570175041 4.237090e-01   16 70278900 70279045 146 - 0.152 0.000 -13.123
ENSG00000090861 E054 0.0000000       16 70279046 70279340 295 -      
ENSG00000090861 E055 0.2542726 0.2902757464 2.094261e-01   16 70279409 70279653 245 - 0.000 0.196 12.851
ENSG00000090861 E056 27.5498713 0.0005141926 6.317162e-04 1.044807e-02 16 70282620 70282784 165 - 1.529 1.333 -0.677
ENSG00000090861 E057 0.1271363 0.0123632560 3.961007e-01   16 70289216 70289317 102 - 0.000 0.109 12.695
ENSG00000090861 E058 11.3491976 0.0137676574 2.457737e-02 1.439570e-01 16 70289421 70289529 109 - 1.173 0.953 -0.799
ENSG00000090861 E059 0.2441403 0.0162126172 8.155383e-01   16 70289530 70289580 51 - 0.083 0.109 0.438
ENSG00000090861 E060 0.0000000       16 70289593 70289707 115 -      

Help

Please Click HERE to learn more details about the results from DEXseq.