ENSG00000090863

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000447066 ENSG00000090863 No_inf pgKDN_inf GLG1 protein_coding protein_coding 40.57782 32.91679 43.44296 1.204106 1.159053 0.4001927 4.583743 1.797714 5.920167 0.7217714 0.6071500 1.7139065 0.10839167 0.05500 0.137225 0.082225 0.4532845 0.0218901 FALSE TRUE
ENST00000562090 ENSG00000090863 No_inf pgKDN_inf GLG1 protein_coding nonsense_mediated_decay 40.57782 32.91679 43.44296 1.204106 1.159053 0.4001927 3.514251 0.000000 5.672747 0.0000000 2.1036191 9.1504448 0.08013333 0.00000 0.131400 0.131400 0.0218901 0.0218901 TRUE TRUE
ENST00000567951 ENSG00000090863 No_inf pgKDN_inf GLG1 protein_coding nonsense_mediated_decay 40.57782 32.91679 43.44296 1.204106 1.159053 0.4001927 13.189624 10.683748 13.373984 0.4920909 2.1448467 0.3237401 0.32362500 0.32430 0.306275 -0.018025 0.9372689 0.0218901 FALSE TRUE
MSTRG.11481.3 ENSG00000090863 No_inf pgKDN_inf GLG1 protein_coding   40.57782 32.91679 43.44296 1.204106 1.159053 0.4001927 15.389438 14.479822 15.632890 0.6693903 0.3308587 0.1104672 0.38550833 0.44175 0.360400 -0.081350 0.6417767 0.0218901 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000090863 E001 0.9654499 2.019780e-01 3.286344e-01 6.211083e-01 16 74447427 74447439 13 - 0.376 0.183 -1.396
ENSG00000090863 E002 1.3467025 7.854723e-02 9.669397e-01 9.933545e-01 16 74447440 74447442 3 - 0.376 0.363 -0.073
ENSG00000090863 E003 295.7745953 9.429187e-05 1.066862e-25 4.566676e-23 16 74447443 74452026 4584 - 2.382 2.551 0.565
ENSG00000090863 E004 32.2967407 4.285448e-04 6.391790e-01 8.465200e-01 16 74452027 74452131 105 - 1.510 1.534 0.082
ENSG00000090863 E005 125.4927126 1.473875e-04 4.537050e-01 7.264051e-01 16 74452132 74452789 658 - 2.112 2.091 -0.068
ENSG00000090863 E006 103.7640784 1.574944e-04 7.332669e-01 8.939164e-01 16 74452790 74453170 381 - 2.015 2.025 0.031
ENSG00000090863 E007 35.9639685 3.776017e-04 5.737637e-01 8.090198e-01 16 74453171 74453188 18 - 1.554 1.581 0.093
ENSG00000090863 E008 73.3675117 2.339933e-04 5.957982e-01 8.222680e-01 16 74453189 74453334 146 - 1.880 1.861 -0.064
ENSG00000090863 E009 50.7415560 5.881110e-04 6.027147e-01 8.266361e-01 16 74456649 74456755 107 - 1.703 1.725 0.073
ENSG00000090863 E010 43.4562625 3.248632e-04 6.617376e-01 8.587987e-01 16 74457874 74457994 121 - 1.657 1.637 -0.069
ENSG00000090863 E011 0.2537694 1.601741e-02 2.000792e-01   16 74457995 74458294 300 - 0.000 0.183 9.885
ENSG00000090863 E012 35.3535603 3.931805e-04 3.022639e-05 8.708495e-04 16 74459682 74459789 108 - 1.651 1.438 -0.728
ENSG00000090863 E013 1.9966071 6.937203e-03 2.265427e-02 1.370539e-01 16 74461489 74461783 295 - 0.282 0.617 1.776
ENSG00000090863 E014 1.9872573 6.937838e-03 7.833110e-02 2.865375e-01 16 74461784 74462093 310 - 0.332 0.588 1.329
ENSG00000090863 E015 34.7147711 4.233950e-04 1.926434e-01 4.724961e-01 16 74462094 74462195 102 - 1.584 1.517 -0.227
ENSG00000090863 E016 55.9553120 3.532160e-03 3.738740e-01 6.615718e-01 16 74462488 74462630 143 - 1.776 1.733 -0.143
ENSG00000090863 E017 0.9797704 1.985837e-02 8.534945e-01 9.483216e-01 16 74462631 74463355 725 - 0.282 0.311 0.191
ENSG00000090863 E018 51.6861590 2.750678e-04 2.466720e-01 5.373059e-01 16 74463356 74463479 124 - 1.744 1.696 -0.165
ENSG00000090863 E019 44.2101435 3.264839e-04 1.044669e-01 3.377889e-01 16 74465676 74465813 138 - 1.689 1.616 -0.249
ENSG00000090863 E020 16.6962117 7.906168e-04 4.013772e-01 6.845395e-01 16 74467756 74467758 3 - 1.276 1.216 -0.212
ENSG00000090863 E021 33.0547061 9.134937e-04 3.379400e-01 6.297580e-01 16 74467759 74467848 90 - 1.507 1.557 0.170
ENSG00000090863 E022 3.3482431 3.125359e-02 5.618661e-02 2.363504e-01 16 74467849 74468253 405 - 0.486 0.756 1.191
ENSG00000090863 E023 2.8630836 4.952630e-03 8.712368e-03 7.329525e-02 16 74468254 74468945 692 - 0.376 0.736 1.694
ENSG00000090863 E024 35.3018755 1.801172e-03 9.885197e-01 1.000000e+00 16 74468946 74469063 118 - 1.560 1.560 0.001
ENSG00000090863 E025 2.3597975 5.887174e-03 5.877917e-02 2.430572e-01 16 74469064 74469984 921 - 0.376 0.643 1.307
ENSG00000090863 E026 25.9678903 5.343118e-04 3.818530e-01 6.681792e-01 16 74469985 74470073 89 - 1.455 1.403 -0.177
ENSG00000090863 E027 29.1535046 4.827675e-04 5.595588e-01 8.005954e-01 16 74471173 74471286 114 - 1.495 1.462 -0.112
ENSG00000090863 E028 21.1709814 6.366590e-04 5.174308e-01 7.729218e-01 16 74472349 74472411 63 - 1.325 1.366 0.141
ENSG00000090863 E029 0.7502944 3.154240e-01 1.781993e-01 4.529644e-01 16 74472412 74472525 114 - 0.090 0.363 2.513
ENSG00000090863 E030 0.5971958 1.498562e-02 2.235216e-01 5.111390e-01 16 74472526 74472589 64 - 0.282 0.101 -1.809
ENSG00000090863 E031 0.7244581 1.388048e-02 5.121051e-01 7.691995e-01 16 74472590 74472634 45 - 0.282 0.183 -0.809
ENSG00000090863 E032 2.5942460 5.700699e-03 1.668172e-01 4.372202e-01 16 74472635 74472950 316 - 0.452 0.643 0.892
ENSG00000090863 E033 1.9931775 7.089144e-03 2.263476e-02 1.369666e-01 16 74474172 74474545 374 - 0.282 0.617 1.776
ENSG00000090863 E034 22.4605718 1.021790e-03 7.860249e-01 9.175479e-01 16 74474546 74474632 87 - 1.379 1.361 -0.060
ENSG00000090863 E035 28.6612066 4.895837e-04 4.610356e-01 7.320564e-01 16 74477396 74477533 138 - 1.491 1.450 -0.142
ENSG00000090863 E036 14.3855425 1.068162e-03 5.762077e-01 8.104837e-01 16 74480241 74480274 34 - 1.207 1.164 -0.153
ENSG00000090863 E037 26.9524358 5.591363e-04 1.234978e-02 9.204978e-02 16 74480275 74480394 120 - 1.510 1.366 -0.498
ENSG00000090863 E038 27.3305775 5.004601e-04 1.605611e-02 1.098982e-01 16 74483023 74483124 102 - 1.513 1.376 -0.474
ENSG00000090863 E039 30.1072412 4.763929e-04 5.567750e-03 5.355646e-02 16 74485796 74485917 122 - 1.560 1.408 -0.521
ENSG00000090863 E040 37.9224673 6.522846e-03 8.142039e-02 2.933223e-01 16 74491001 74491215 215 - 1.637 1.534 -0.351
ENSG00000090863 E041 27.5495856 6.837449e-03 3.929579e-02 1.919554e-01 16 74492957 74493140 184 - 1.516 1.380 -0.468
ENSG00000090863 E042 13.9489020 3.002520e-03 3.377708e-02 1.748975e-01 16 74494760 74494831 72 - 1.249 1.079 -0.606
ENSG00000090863 E043 19.0768804 6.696438e-03 7.672636e-02 2.832222e-01 16 74496441 74496599 159 - 1.362 1.229 -0.463
ENSG00000090863 E044 8.6574747 1.967312e-03 6.172923e-01 8.342683e-01 16 74496600 74496628 29 - 1.007 0.959 -0.177
ENSG00000090863 E045 8.1925121 1.739134e-03 8.582672e-01 9.505500e-01 16 74496629 74496644 16 - 0.955 0.972 0.062
ENSG00000090863 E046 25.1109648 5.832089e-04 3.218908e-01 6.148701e-01 16 74503531 74503735 205 - 1.444 1.385 -0.204
ENSG00000090863 E047 7.2110503 2.068382e-02 9.148699e-01 9.732459e-01 16 74503736 74503746 11 - 0.909 0.920 0.044
ENSG00000090863 E048 11.9119980 3.945622e-03 1.889361e-01 4.675334e-01 16 74508839 74508925 87 - 1.162 1.049 -0.406
ENSG00000090863 E049 5.9158532 2.380996e-03 2.366656e-02 1.407157e-01 16 74532121 74532153 33 - 0.944 0.692 -0.989
ENSG00000090863 E050 0.1176306 1.178152e-02 6.140124e-01   16 74563106 74563325 220 - 0.090 0.000 -9.610
ENSG00000090863 E051 9.5865658 1.402672e-03 1.230939e-01 3.713058e-01 16 74606657 74606827 171 - 1.087 0.947 -0.517
ENSG00000090863 E052 5.4356937 2.832887e-03 3.598671e-02 1.819885e-01 16 74606828 74606938 111 - 0.909 0.669 -0.956
ENSG00000090863 E053 6.1490071 3.122731e-03 1.336306e-02 9.702790e-02 16 74606939 74607144 206 - 0.966 0.692 -1.072

Help

Please Click HERE to learn more details about the results from DEXseq.