ENSG00000091651

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000219097 ENSG00000091651 No_inf pgKDN_inf ORC6 protein_coding protein_coding 27.0512 28.99471 24.92045 0.8068373 1.382245 -0.2183782 5.623668 0.0000000 10.996020 0.0000000 1.3397659 10.1040771 0.2241917 0.000000 0.448375 0.448375 2.649683e-15 2.649683e-15 FALSE TRUE
ENST00000567000 ENSG00000091651 No_inf pgKDN_inf ORC6 protein_coding retained_intron 27.0512 28.99471 24.92045 0.8068373 1.382245 -0.2183782 2.230440 2.5386560 1.430842 0.8119679 0.3947477 -0.8228242 0.0813250 0.085650 0.055825 -0.029825 8.540557e-01 2.649683e-15 FALSE FALSE
ENST00000569239 ENSG00000091651 No_inf pgKDN_inf ORC6 protein_coding retained_intron 27.0512 28.99471 24.92045 0.8068373 1.382245 -0.2183782 10.536193 16.3822003 6.949689 0.7990521 0.8833696 -1.2359148 0.3813000 0.564025 0.275875 -0.288150 1.564689e-03 2.649683e-15 FALSE TRUE
ENST00000575571 ENSG00000091651 No_inf pgKDN_inf ORC6 protein_coding protein_coding_CDS_not_defined 27.0512 28.99471 24.92045 0.8068373 1.382245 -0.2183782 4.894969 5.3749423 2.396677 0.6239896 2.3966771 -1.1618883 0.1719250 0.185675 0.085050 -0.100625 1.280869e-01 2.649683e-15   FALSE
MSTRG.11117.2 ENSG00000091651 No_inf pgKDN_inf ORC6 protein_coding   27.0512 28.99471 24.92045 0.8068373 1.382245 -0.2183782 1.637343 0.9523123 1.749476 0.6053960 1.2175179 0.8705689 0.0632500 0.033300 0.078300 0.045000 9.602787e-01 2.649683e-15 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000091651 E001 0.7437487 0.014099472 0.259930378 0.55256336 16 46689630 46689642 13 + 0.155 0.325 1.373
ENSG00000091651 E002 0.8710110 0.013214091 0.140411000 0.39874299 16 46689643 46689658 16 + 0.155 0.379 1.695
ENSG00000091651 E003 1.8236752 0.008901232 0.779106993 0.91499838 16 46689659 46689681 23 + 0.468 0.427 -0.212
ENSG00000091651 E004 2.4197985 0.059495163 0.486687966 0.75025092 16 46689682 46689696 15 + 0.579 0.470 -0.520
ENSG00000091651 E005 3.2744428 0.005420252 0.489891043 0.75273592 16 46689697 46689706 10 + 0.668 0.578 -0.393
ENSG00000091651 E006 5.6759951 0.026818382 0.144606638 0.40481752 16 46689707 46689770 64 + 0.897 0.714 -0.720
ENSG00000091651 E007 0.3637832 0.137968806 0.781080282   16 46689771 46689829 59 + 0.155 0.107 -0.628
ENSG00000091651 E008 0.1176306 0.011806982 0.693773510   16 46690786 46690990 205 + 0.085 0.000 -8.865
ENSG00000091651 E009 6.6196577 0.014714530 0.008841141 0.07405468 16 46690991 46691057 67 + 0.992 0.690 -1.178
ENSG00000091651 E010 8.6079246 0.001786535 0.224208096 0.51174487 16 46691058 46691120 63 + 1.029 0.916 -0.419
ENSG00000091651 E011 15.1821594 0.001037941 0.296924764 0.59017285 16 46692382 46692545 164 + 1.239 1.166 -0.260
ENSG00000091651 E012 8.9345743 0.020984451 0.369396257 0.65759316 16 46693093 46693182 90 + 0.952 1.042 0.333
ENSG00000091651 E013 1.4800085 0.009707525 0.311578707 0.60478221 16 46693183 46694519 1337 + 0.317 0.470 0.858
ENSG00000091651 E014 0.3724075 0.016763740 0.436071869   16 46694937 46694938 2 + 0.085 0.192 1.373
ENSG00000091651 E015 0.9976717 0.011849594 0.073401430 0.27549288 16 46694939 46695084 146 + 0.155 0.427 1.958
ENSG00000091651 E016 3.7078774 0.042043132 0.056332349 0.23667332 16 46695109 46695561 453 + 0.527 0.799 1.161
ENSG00000091651 E017 9.6762022 0.001616569 0.201721321 0.48408978 16 46695562 46695674 113 + 0.973 1.084 0.409
ENSG00000091651 E018 3.1116668 0.005051017 0.004280816 0.04453733 16 46695675 46696016 342 + 0.399 0.779 1.735
ENSG00000091651 E019 8.3408937 0.002204789 0.118265300 0.36328287 16 46696017 46696085 69 + 0.897 1.042 0.543
ENSG00000091651 E020 0.8793160 0.034169440 0.024155766 0.14237189 16 46696086 46696219 134 + 0.085 0.427 2.958
ENSG00000091651 E021 62.9490550 0.000439848 0.269034349 0.56263670 16 46697458 46698394 937 + 1.818 1.786 -0.106

Help

Please Click HERE to learn more details about the results from DEXseq.