ENSG00000093144

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368291 ENSG00000093144 No_inf pgKDN_inf ECHDC1 protein_coding protein_coding 69.29058 70.58599 78.59927 2.150005 1.787702 0.1551133 4.268219 0.000000 8.399441 0.00000000 2.000022 9.7158661 0.06115833 0.000000 0.106875 0.106875 5.764046e-10 5.764046e-10 FALSE TRUE
ENST00000368295 ENSG00000093144 No_inf pgKDN_inf ECHDC1 protein_coding nonsense_mediated_decay 69.29058 70.58599 78.59927 2.150005 1.787702 0.1551133 8.783242 15.660966 5.885588 0.07753549 2.163839 -1.4103865 0.12564167 0.222575 0.075525 -0.147050 3.180099e-01 5.764046e-10 TRUE TRUE
ENST00000454859 ENSG00000093144 No_inf pgKDN_inf ECHDC1 protein_coding protein_coding 69.29058 70.58599 78.59927 2.150005 1.787702 0.1551133 42.471266 36.790932 53.219074 1.10310029 1.583782 0.5324722 0.61365833 0.521950 0.678900 0.156950 5.197660e-02 5.764046e-10 FALSE TRUE
ENST00000528402 ENSG00000093144 No_inf pgKDN_inf ECHDC1 protein_coding protein_coding 69.29058 70.58599 78.59927 2.150005 1.787702 0.1551133 5.982026 7.604113 6.007384 0.62676073 3.165325 -0.3395395 0.08552500 0.107675 0.074250 -0.033425 7.405846e-01 5.764046e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000093144 E001 1.2230555 0.0106448171 9.065338e-01 0.970223458 6 127288712 127288719 8 - 0.338 0.356 0.109
ENSG00000093144 E002 11.0424424 0.0014670947 3.277410e-01 0.620301388 6 127288720 127288761 42 - 1.037 1.121 0.302
ENSG00000093144 E003 156.3863198 0.0001265111 2.687676e-06 0.000109567 6 127288762 127289266 505 - 2.140 2.248 0.362
ENSG00000093144 E004 135.9848257 0.0001468410 7.999679e-02 0.290307283 6 127289267 127289631 365 - 2.114 2.158 0.146
ENSG00000093144 E005 23.4968836 0.0055750688 6.356346e-01 0.844548607 6 127289632 127289633 2 - 1.373 1.405 0.110
ENSG00000093144 E006 80.9796263 0.0001907341 7.803624e-01 0.915268722 6 127289634 127289779 146 - 1.909 1.918 0.031
ENSG00000093144 E007 67.7246131 0.0008734049 6.459880e-01 0.850210974 6 127289780 127289868 89 - 1.845 1.828 -0.057
ENSG00000093144 E008 35.4862009 0.0005089698 1.277303e-01 0.378899733 6 127289869 127289876 8 - 1.598 1.522 -0.259
ENSG00000093144 E009 59.0926435 0.0002468204 2.520803e-02 0.146137951 6 127289877 127289928 52 - 1.820 1.733 -0.292
ENSG00000093144 E010 64.4092587 0.0036051934 2.721523e-01 0.565985373 6 127289929 127289987 59 - 1.839 1.791 -0.164
ENSG00000093144 E011 59.9140104 0.0003049960 1.953001e-01 0.475563370 6 127289988 127290045 58 - 1.809 1.759 -0.168
ENSG00000093144 E012 57.9273020 0.0067992829 6.480388e-01 0.851391487 6 127290046 127290109 64 - 1.781 1.759 -0.074
ENSG00000093144 E013 115.4208714 0.0001384771 9.412615e-02 0.319301939 6 127290110 127290277 168 - 2.043 2.088 0.152
ENSG00000093144 E014 1.8692473 0.0794046287 8.551817e-02 0.302666642 6 127294504 127294744 241 - 0.288 0.579 1.569
ENSG00000093144 E015 0.9711764 0.0115153875 5.494321e-01 0.794193759 6 127313066 127313591 526 - 0.338 0.246 -0.628
ENSG00000093144 E016 49.4976451 0.0002990883 7.764609e-01 0.914152388 6 127314816 127314854 39 - 1.709 1.697 -0.040
ENSG00000093144 E017 30.4084696 0.0004992998 6.306806e-01 0.841500339 6 127314855 127314858 4 - 1.510 1.484 -0.088
ENSG00000093144 E018 32.2146966 0.0004416747 3.873957e-01 0.673312666 6 127314859 127314865 7 - 1.543 1.498 -0.154
ENSG00000093144 E019 35.4883031 0.0003872073 1.955554e-01 0.475884971 6 127314866 127314896 31 - 1.593 1.529 -0.219
ENSG00000093144 E020 2.6225340 0.0788521848 2.692168e-02 0.152440288 6 127314897 127315134 238 - 0.338 0.705 1.788
ENSG00000093144 E021 0.4893776 0.1070149270 9.306118e-01   6 127315135 127315138 4 - 0.168 0.179 0.110
ENSG00000093144 E022 6.0940843 0.0268389786 3.875504e-03 0.041521933 6 127315139 127315860 722 - 0.633 0.996 1.432
ENSG00000093144 E023 1.2317448 0.0101025976 4.563842e-01 0.728722263 6 127315934 127315974 41 - 0.288 0.402 0.694
ENSG00000093144 E024 0.6147850 0.0190367986 5.988562e-01 0.824043114 6 127315975 127316081 107 - 0.168 0.246 0.694
ENSG00000093144 E025 1.5932334 0.0084663825 6.824267e-01 0.868584822 6 127316256 127316449 194 - 0.383 0.444 0.332
ENSG00000093144 E026 19.7141026 0.0009709428 8.735644e-02 0.306378103 6 127316450 127316458 9 - 1.369 1.256 -0.394
ENSG00000093144 E027 31.9060225 0.0011628722 6.806785e-02 0.263220490 6 127316459 127316502 44 - 1.563 1.466 -0.335
ENSG00000093144 E028 0.3724725 0.0166982792 5.378182e-01   6 127326496 127326574 79 - 0.092 0.179 1.109
ENSG00000093144 E029 0.4987572 0.0255875271 2.872694e-01   6 127326881 127326997 117 - 0.092 0.246 1.694
ENSG00000093144 E030 0.3811266 0.0252924511 9.072486e-02   6 127326998 127327001 4 - 0.000 0.246 11.587
ENSG00000093144 E031 59.8802854 0.0005347785 1.223111e-01 0.369958213 6 127327002 127327144 143 - 1.814 1.753 -0.203
ENSG00000093144 E032 0.3628408 0.0166733401 6.315561e-01   6 127329822 127329882 61 - 0.168 0.098 -0.891
ENSG00000093144 E033 56.4979061 0.0002841658 1.665904e-01 0.436965673 6 127330809 127331030 222 - 1.786 1.731 -0.184
ENSG00000093144 E034 1.1240875 0.0134239021 7.166592e-02 0.271314556 6 127331830 127331867 38 - 0.168 0.444 1.917
ENSG00000093144 E035 0.0000000       6 127341569 127341638 70 -      
ENSG00000093144 E036 0.1186381 0.0118544492 5.801671e-01   6 127342356 127342875 520 - 0.092 0.000 -10.917
ENSG00000093144 E037 0.9965746 0.1014168456 1.558056e-01 0.421853694 6 127342961 127343335 375 - 0.168 0.402 1.695
ENSG00000093144 E038 27.7659441 0.0007447566 7.148581e-02 0.270904712 6 127343336 127343609 274 - 1.507 1.405 -0.350

Help

Please Click HERE to learn more details about the results from DEXseq.