ENSG00000093183

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264454 ENSG00000093183 No_inf pgKDN_inf SEC22C protein_coding protein_coding 16.01559 11.7452 17.92814 0.7470483 1.174821 0.6097317 2.6015139 0.0000000 4.703557 0.0000000 1.5771101 8.8806724 0.15364167 0.000000 0.277925 0.277925 0.03135684 0.03135684 FALSE TRUE
ENST00000273156 ENSG00000093183 No_inf pgKDN_inf SEC22C protein_coding protein_coding 16.01559 11.7452 17.92814 0.7470483 1.174821 0.6097317 8.6897739 6.4414381 9.675879 0.8130535 0.6655106 0.5862622 0.54343333 0.541725 0.542250 0.000525 1.00000000 0.03135684 FALSE TRUE
ENST00000449617 ENSG00000093183 No_inf pgKDN_inf SEC22C protein_coding nonsense_mediated_decay 16.01559 11.7452 17.92814 0.7470483 1.174821 0.6097317 0.2765447 0.6826614 0.000000 0.3789559 0.0000000 -6.1140784 0.02468333 0.065625 0.000000 -0.065625 0.17216183 0.03135684 FALSE TRUE
ENST00000451653 ENSG00000093183 No_inf pgKDN_inf SEC22C protein_coding protein_coding 16.01559 11.7452 17.92814 0.7470483 1.174821 0.6097317 2.8783769 3.8999033 1.767936 0.1978848 1.7679356 -1.1369299 0.19129167 0.335750 0.085550 -0.250200 0.05560373 0.03135684 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000093183 E001 0.0000000       3 42547969 42547970 2 -      
ENSG00000093183 E002 1.5799529 0.2480413802 0.88594005 0.96182070 3 42547971 42548003 33 - 0.418 0.395 -0.126
ENSG00000093183 E003 12.2875249 0.0011326627 0.80843825 0.92929046 3 42548004 42548182 179 - 1.111 1.129 0.064
ENSG00000093183 E004 39.4620131 0.0003567693 0.00997296 0.08010838 3 42548183 42548657 475 - 1.551 1.664 0.385
ENSG00000093183 E005 129.4711955 0.0001896942 0.90574075 0.96992399 3 42548658 42553448 4791 - 2.112 2.108 -0.013
ENSG00000093183 E006 5.0019922 0.0033407881 0.44689448 0.72112155 3 42555930 42555930 1 - 0.736 0.822 0.343
ENSG00000093183 E007 8.5277286 0.0018439473 0.50948759 0.76733336 3 42555931 42555995 65 - 0.948 1.008 0.224
ENSG00000093183 E008 11.0534534 0.0013247599 0.86937239 0.95510013 3 42557578 42557696 119 - 1.083 1.067 -0.057
ENSG00000093183 E009 0.1265070 0.0123460977 0.36033626   3 42561115 42561116 2 - 0.000 0.113 10.897
ENSG00000093183 E010 12.0184633 0.0012149308 0.67674471 0.86599578 3 42561117 42561214 98 - 1.124 1.089 -0.128
ENSG00000093183 E011 11.5174374 0.0013005837 0.35076436 0.64103162 3 42561215 42561296 82 - 1.124 1.045 -0.289
ENSG00000093183 E012 5.5782520 0.0814075216 0.56741260 0.80523699 3 42563523 42563523 1 - 0.849 0.759 -0.353
ENSG00000093183 E013 5.9397406 0.0723493582 0.52162705 0.77544645 3 42563524 42563544 21 - 0.873 0.781 -0.358
ENSG00000093183 E014 4.4674474 0.1923549141 0.27490893 0.56840859 3 42563545 42563546 2 - 0.796 0.630 -0.687
ENSG00000093183 E015 8.2310212 0.0060238903 0.27447363 0.56805299 3 42563547 42563608 62 - 1.004 0.893 -0.414
ENSG00000093183 E016 9.5804909 0.0013954352 0.49833045 0.75880730 3 42563609 42563686 78 - 1.045 0.982 -0.231
ENSG00000093183 E017 0.8813647 0.1751823814 0.03355215 0.17426828 3 42563765 42563844 80 - 0.080 0.444 3.140
ENSG00000093183 E018 0.2441403 0.0165832665 0.76181766   3 42563845 42563880 36 - 0.080 0.113 0.555
ENSG00000093183 E019 0.2356421 0.0158101135 0.40676607   3 42563881 42563888 8 - 0.147 0.000 -11.954
ENSG00000093183 E020 0.6151632 0.3693773008 0.59956534 0.82454408 3 42563889 42563926 38 - 0.147 0.276 1.139
ENSG00000093183 E021 0.7338663 0.2291624545 0.76873986 0.91059509 3 42563927 42563980 54 - 0.206 0.276 0.554
ENSG00000093183 E022 0.1176306 0.0117829027 0.80046758   3 42563981 42564415 435 - 0.080 0.000 -11.035
ENSG00000093183 E023 0.0000000       3 42565776 42565883 108 -      
ENSG00000093183 E024 0.2457744 0.0169384679 0.76283830   3 42566744 42566836 93 - 0.080 0.113 0.555
ENSG00000093183 E025 13.0531049 0.0011116912 0.08278861 0.29652816 3 42568865 42569073 209 - 1.197 1.056 -0.506
ENSG00000093183 E026 0.1265070 0.0123460977 0.36033626   3 42573400 42573547 148 - 0.000 0.113 10.897
ENSG00000093183 E027 0.1272623 0.0124393609 0.36030161   3 42579477 42579593 117 - 0.000 0.113 10.897
ENSG00000093183 E028 0.0000000       3 42580443 42580505 63 -      
ENSG00000093183 E029 0.0000000       3 42581312 42581365 54 -      
ENSG00000093183 E030 0.0000000       3 42581846 42582028 183 -      
ENSG00000093183 E031 0.0000000       3 42582193 42582327 135 -      
ENSG00000093183 E032 0.0000000       3 42587411 42587562 152 -      
ENSG00000093183 E033 0.3717469 0.0165995953 0.37108901   3 42600411 42600524 114 - 0.080 0.202 1.555
ENSG00000093183 E034 0.0000000       3 42600960 42601080 121 -      

Help

Please Click HERE to learn more details about the results from DEXseq.