ENSG00000095015

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000399503 ENSG00000095015 No_inf pgKDN_inf MAP3K1 protein_coding protein_coding 11.43015 20.85139 7.429578 0.6361866 0.3219606 -1.487543 6.963187 10.57411 6.287010 0.3452873 0.1185191 -0.7491604 0.6782417 0.507175 0.85315 0.345975 0.01709627 0.01709627 FALSE TRUE
ENST00000469188 ENSG00000095015 No_inf pgKDN_inf MAP3K1 protein_coding retained_intron 11.43015 20.85139 7.429578 0.6361866 0.3219606 -1.487543 4.466965 10.27728 1.142568 0.3637035 0.4330315 -3.1579387 0.3217583 0.492825 0.14685 -0.345975 0.03344072 0.01709627 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000095015 E001 5.482692 0.0470786065 7.664855e-04 1.223790e-02 5 56815549 56816055 507 + 1.047 0.593 -1.798
ENSG00000095015 E002 2.216103 0.0143825066 1.562941e-01 4.225577e-01 5 56856600 56856750 151 + 0.615 0.404 -1.023
ENSG00000095015 E003 0.126854 0.0122797651 1.000000e+00   5 56859715 56859915 201 + 0.000 0.062 8.121
ENSG00000095015 E004 5.222438 0.0031052318 9.692022e-01 9.936412e-01 5 56864734 56864934 201 + 0.754 0.749 -0.023
ENSG00000095015 E005 7.500166 0.0024784067 2.436398e-01 5.336341e-01 5 56865340 56865456 117 + 0.783 0.915 0.509
ENSG00000095015 E006 8.332177 0.0023539576 9.942985e-01 1.000000e+00 5 56865829 56865977 149 + 0.925 0.923 -0.008
ENSG00000095015 E007 3.959605 0.0139054314 4.711324e-01 7.386214e-01 5 56871910 56872031 122 + 0.723 0.626 -0.412
ENSG00000095015 E008 4.578233 0.0041802381 3.705008e-01 6.588122e-01 5 56872641 56872722 82 + 0.783 0.671 -0.460
ENSG00000095015 E009 6.348262 0.0027793848 8.929582e-01 9.645020e-01 5 56872825 56873005 181 + 0.810 0.825 0.057
ENSG00000095015 E010 12.483217 0.0012358877 7.010031e-02 2.679511e-01 5 56875032 56875310 279 + 1.188 1.035 -0.554
ENSG00000095015 E011 6.021759 0.0023423937 1.425527e-02 1.014800e-01 5 56878980 56879101 122 + 0.981 0.712 -1.049
ENSG00000095015 E012 5.575023 0.0034503666 4.651035e-01 7.343486e-01 5 56880711 56880802 92 + 0.836 0.749 -0.345
ENSG00000095015 E013 11.765492 0.0014476712 1.741135e-01 4.477061e-01 5 56881083 56881272 190 + 1.142 1.022 -0.435
ENSG00000095015 E014 63.689069 0.0002490612 3.529280e-03 3.893436e-02 5 56881570 56882866 1297 + 1.838 1.726 -0.378
ENSG00000095015 E015 13.092367 0.0010853185 3.578214e-02 1.814474e-01 5 56883527 56883679 153 + 1.220 1.047 -0.622
ENSG00000095015 E016 11.762653 0.0012083919 1.729471e-01 4.458894e-01 5 56884664 56884826 163 + 1.142 1.022 -0.435
ENSG00000095015 E017 6.337903 0.0438899046 8.418419e-01 9.432421e-01 5 56885932 56885952 21 + 0.836 0.815 -0.082
ENSG00000095015 E018 11.937826 0.0244666615 9.848449e-01 9.989951e-01 5 56885953 56886063 111 + 1.062 1.064 0.009
ENSG00000095015 E019 13.032810 0.0012464333 6.239400e-01 8.381781e-01 5 56887378 56887520 143 + 1.130 1.087 -0.155
ENSG00000095015 E020 2.518595 0.0124353205 4.823594e-02 2.162005e-01 5 56887521 56888225 705 + 0.250 0.576 1.825
ENSG00000095015 E021 14.511959 0.0010165326 4.307745e-01 7.085511e-01 5 56888226 56888357 132 + 1.188 1.123 -0.232
ENSG00000095015 E022 257.593437 0.0001186450 3.001174e-10 2.800438e-08 5 56893531 56896152 2622 + 2.289 2.383 0.316

Help

Please Click HERE to learn more details about the results from DEXseq.