ENSG00000095139

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264028 ENSG00000095139 No_inf pgKDN_inf ARCN1 protein_coding protein_coding 106.5329 81.26923 127.6298 1.325958 0.6176545 0.6511191 78.55976 50.01215 99.77206 0.9614736 2.075242 0.9962134 0.7248500 0.61640 0.781700 0.165300 0.0005740077 0.0005740077 FALSE TRUE
ENST00000534182 ENSG00000095139 No_inf pgKDN_inf ARCN1 protein_coding protein_coding 106.5329 81.26923 127.6298 1.325958 0.6176545 0.6511191 26.12391 30.78716 26.54714 2.4525589 2.323194 -0.2136976 0.2585417 0.37765 0.208125 -0.169525 0.0119922038 0.0005740077 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000095139 E001 0.2357071 0.0156692230 4.516138e-01   11 118572390 118572408 19 + 0.141 0.000 -8.971
ENSG00000095139 E002 2.4114345 0.0060976016 4.378158e-01 7.140573e-01 11 118572409 118572423 15 + 0.566 0.459 -0.516
ENSG00000095139 E003 6.7201223 0.0021113087 1.653068e-02 1.119776e-01 11 118572424 118572435 12 + 0.966 0.705 -1.019
ENSG00000095139 E004 21.0406845 0.0011014638 1.266613e-01 3.772767e-01 11 118572436 118572550 115 + 1.370 1.275 -0.331
ENSG00000095139 E005 0.6063545 0.0196357154 9.421237e-01 9.837089e-01 11 118573620 118573783 164 + 0.197 0.211 0.122
ENSG00000095139 E006 45.0539562 0.0054827265 2.020565e-01 4.845367e-01 11 118581246 118581401 156 + 1.677 1.616 -0.207
ENSG00000095139 E007 41.6075497 0.0067748937 6.560139e-01 8.559419e-01 11 118581402 118581509 108 + 1.627 1.610 -0.059
ENSG00000095139 E008 77.7767931 0.0002115973 4.993427e-01 7.595339e-01 11 118583179 118583358 180 + 1.893 1.877 -0.053
ENSG00000095139 E009 88.1245155 0.0021918307 2.399929e-02 1.418807e-01 11 118583809 118584014 206 + 1.970 1.892 -0.264
ENSG00000095139 E010 77.9866653 0.0002106705 4.130613e-01 6.939915e-01 11 118584480 118584644 165 + 1.896 1.876 -0.070
ENSG00000095139 E011 76.3691750 0.0002641081 1.607215e-01 4.287087e-01 11 118590341 118590506 166 + 1.895 1.853 -0.141
ENSG00000095139 E012 83.6013596 0.0042973713 1.435248e-01 4.034644e-01 11 118592709 118592856 148 + 1.939 1.885 -0.182
ENSG00000095139 E013 76.7837849 0.0093582767 5.439928e-01 7.906359e-01 11 118593590 118593698 109 + 1.890 1.868 -0.074
ENSG00000095139 E014 106.8006762 0.0004274259 4.030762e-02 1.946741e-01 11 118597707 118597911 205 + 2.044 1.990 -0.184
ENSG00000095139 E015 439.3963782 0.0014865255 7.285422e-02 2.741657e-01 11 118600625 118601635 1011 + 2.644 2.619 -0.085
ENSG00000095139 E016 793.3669830 0.0008445924 4.268130e-09 3.237656e-07 11 118601636 118603033 1398 + 2.860 2.933 0.244

Help

Please Click HERE to learn more details about the results from DEXseq.