ENSG00000095370

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000314830 ENSG00000095370 No_inf pgKDN_inf SH2D3C protein_coding protein_coding 27.86687 43.33172 21.8278 2.850717 1.188253 -0.9889287 9.965441 6.724205 10.562779 0.5196621 1.0376736 0.6507751 0.4467583 0.157350 0.491100 0.33375 0.002090617 0.002090617 FALSE TRUE
ENST00000373277 ENSG00000095370 No_inf pgKDN_inf SH2D3C protein_coding protein_coding 27.86687 43.33172 21.8278 2.850717 1.188253 -0.9889287 11.514159 23.484421 8.318685 3.1433366 0.6765347 -1.4961576 0.3568333 0.547025 0.379775 -0.16725 0.455263979 0.002090617 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000095370 E001 0.2533610 0.0160315722 6.222029e-01   9 127738252 127738316 65 - 0.000 0.127 9.476
ENSG00000095370 E002 0.4985061 0.0327229907 7.922970e-01   9 127738317 127738317 1 - 0.131 0.179 0.525
ENSG00000095370 E003 0.8701583 0.4891407796 9.536782e-01 9.885787e-01 9 127738318 127738322 5 - 0.232 0.266 0.259
ENSG00000095370 E004 2.7442605 0.1997664645 5.906813e-01 8.188681e-01 9 127738323 127738355 33 - 0.442 0.589 0.705
ENSG00000095370 E005 26.2264981 0.0013190844 3.382787e-01 6.300409e-01 9 127738356 127738485 130 - 1.360 1.419 0.206
ENSG00000095370 E006 113.5850864 0.0002515491 9.608398e-02 3.228478e-01 9 127738486 127738921 436 - 1.992 2.039 0.157
ENSG00000095370 E007 3.0217833 0.0864294506 6.168639e-02 2.495682e-01 9 127739383 127739681 299 - 0.314 0.659 1.748
ENSG00000095370 E008 47.5547152 0.0003228564 6.248725e-01 8.385803e-01 9 127739682 127739888 207 - 1.638 1.659 0.073
ENSG00000095370 E009 1.0131585 0.3245490659 1.121192e-01 3.518992e-01 9 127739889 127739957 69 - 0.000 0.372 12.805
ENSG00000095370 E010 34.4249077 0.0006078912 3.000912e-01 5.930166e-01 9 127740258 127740369 112 - 1.477 1.532 0.190
ENSG00000095370 E011 20.4937978 0.0006816349 5.484552e-01 7.934693e-01 9 127741788 127741844 57 - 1.271 1.312 0.142
ENSG00000095370 E012 25.7395350 0.0005932358 3.385148e-01 6.302323e-01 9 127741845 127741959 115 - 1.434 1.375 -0.203
ENSG00000095370 E013 1.1146481 0.0282341536 9.566020e-01 9.897060e-01 9 127742659 127742848 190 - 0.314 0.305 -0.059
ENSG00000095370 E014 28.1050165 0.0092942715 6.228356e-01 8.375390e-01 9 127742849 127742964 116 - 1.456 1.419 -0.125
ENSG00000095370 E015 30.8878612 0.0004909761 9.074255e-01 9.706042e-01 9 127744564 127744686 123 - 1.466 1.472 0.019
ENSG00000095370 E016 33.8319489 0.0004353294 6.606656e-01 8.583624e-01 9 127744687 127744815 129 - 1.525 1.501 -0.083
ENSG00000095370 E017 21.3659186 0.0006605006 5.265840e-01 7.788718e-01 9 127744816 127744897 82 - 1.287 1.329 0.147
ENSG00000095370 E018 26.7718613 0.0005707790 7.806538e-02 2.858370e-01 9 127744898 127745017 120 - 1.332 1.441 0.377
ENSG00000095370 E019 19.8079698 0.0006755907 9.555747e-02 3.218579e-01 9 127745018 127745072 55 - 1.200 1.319 0.419
ENSG00000095370 E020 18.2867201 0.0007680297 3.066154e-01 5.998184e-01 9 127745073 127745099 27 - 1.200 1.274 0.262
ENSG00000095370 E021 31.2526009 0.0005715021 9.804717e-01 9.978172e-01 9 127747147 127747271 125 - 1.477 1.475 -0.008
ENSG00000095370 E022 10.9095251 0.0029359065 9.243876e-01 9.770881e-01 9 127749211 127749211 1 - 1.051 1.042 -0.035
ENSG00000095370 E023 69.0277238 0.0002134580 5.620660e-01 8.021157e-01 9 127749212 127749665 454 - 1.827 1.804 -0.075
ENSG00000095370 E024 21.4397296 0.0146033113 7.799333e-01 9.152108e-01 9 127751172 127751300 129 - 1.332 1.312 -0.072
ENSG00000095370 E025 0.0000000       9 127754836 127755078 243 -      
ENSG00000095370 E026 0.0000000       9 127755079 127755084 6 -      
ENSG00000095370 E027 0.2537694 0.0160348741 6.223140e-01   9 127755085 127755304 220 - 0.000 0.127 11.636
ENSG00000095370 E028 11.7153118 0.0073391999 2.470093e-01 5.375757e-01 9 127761611 127761650 40 - 0.993 1.104 0.405
ENSG00000095370 E029 0.2541163 0.0160288261 6.223593e-01   9 127762121 127762131 11 - 0.000 0.127 11.636
ENSG00000095370 E030 0.9971685 0.0195369783 6.493407e-01 8.522434e-01 9 127762132 127762391 260 - 0.232 0.305 0.525
ENSG00000095370 E031 0.1265070 0.0123174077 1.000000e+00   9 127762392 127762418 27 - 0.000 0.068 10.691
ENSG00000095370 E032 1.7581319 0.0079261407 1.217134e-01 3.692594e-01 9 127766901 127767271 371 - 0.232 0.482 1.525
ENSG00000095370 E033 7.6287532 0.0118848940 7.070595e-02 2.693118e-01 9 127771186 127771438 253 - 0.748 0.961 0.825
ENSG00000095370 E034 22.7307625 0.0006254542 1.272505e-04 2.888523e-03 9 127773990 127774346 357 - 1.492 1.254 -0.825
ENSG00000095370 E035 8.9650121 0.0217057740 4.274689e-07 2.146658e-05 9 127774347 127774467 121 - 1.263 0.719 -2.031
ENSG00000095370 E036 0.7435314 0.1330833692 9.422586e-01 9.838116e-01 9 127775059 127775085 27 - 0.232 0.225 -0.059
ENSG00000095370 E037 4.3474566 0.0032504578 7.128461e-06 2.549512e-04 9 127778591 127778595 5 - 0.993 0.457 -2.244
ENSG00000095370 E038 6.4131348 0.0021413730 7.192927e-07 3.473083e-05 9 127778596 127778843 248 - 1.126 0.608 -2.019

Help

Please Click HERE to learn more details about the results from DEXseq.