ENSG00000099246

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000375802 ENSG00000099246 No_inf pgKDN_inf RAB18 protein_coding protein_coding 31.90995 25.04629 37.15426 1.520753 1.421203 0.5687429 9.1731614 10.706345 5.086083 2.065051 5.086083 -1.07235241 0.30321667 0.417925 0.137200 -0.280725 0.022533596 0.006682597 FALSE TRUE
ENST00000682173 ENSG00000099246 No_inf pgKDN_inf RAB18 protein_coding nonsense_mediated_decay 31.90995 25.04629 37.15426 1.520753 1.421203 0.5687429 0.7610485 2.283146 0.000000 1.319430 0.000000 -7.84118410 0.02960833 0.088825 0.000000 -0.088825 0.415014494 0.006682597   FALSE
ENST00000683446 ENSG00000099246 No_inf pgKDN_inf RAB18 protein_coding retained_intron 31.90995 25.04629 37.15426 1.520753 1.421203 0.5687429 5.8955466 0.000000 14.908690 0.000000 5.520081 10.54290519 0.15890000 0.000000 0.401825 0.401825 0.006682597 0.006682597   FALSE
ENST00000683755 ENSG00000099246 No_inf pgKDN_inf RAB18 protein_coding protein_coding 31.90995 25.04629 37.15426 1.520753 1.421203 0.5687429 1.5413327 0.000000 4.623998 0.000000 1.550544 8.85611362 0.04120833 0.000000 0.123625 0.123625 0.029028336 0.006682597 FALSE TRUE
ENST00000684501 ENSG00000099246 No_inf pgKDN_inf RAB18 protein_coding protein_coding 31.90995 25.04629 37.15426 1.520753 1.421203 0.5687429 8.5833679 6.228334 6.306326 2.326383 3.640966 0.01792478 0.27655000 0.267225 0.165475 -0.101750 0.835786232 0.006682597 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099246 E001 0.0000000       10 27504174 27504233 60 +      
ENSG00000099246 E002 0.1272623 0.0123547147 0.390314068   10 27504234 27504279 46 + 0.000 0.109 10.360
ENSG00000099246 E003 0.2459655 0.0163389570 0.807258001   10 27504280 27504285 6 + 0.083 0.109 0.451
ENSG00000099246 E004 0.3728195 0.0166271011 0.407249266   10 27504286 27504293 8 + 0.083 0.197 1.451
ENSG00000099246 E005 0.3728195 0.0166271011 0.407249266   10 27504294 27504298 5 + 0.083 0.197 1.451
ENSG00000099246 E006 0.8425346 0.0865118669 0.496757686 0.75767035 10 27504299 27504303 5 + 0.311 0.197 -0.871
ENSG00000099246 E007 0.8425346 0.0865118669 0.496757686 0.75767035 10 27504304 27504311 8 + 0.311 0.197 -0.871
ENSG00000099246 E008 0.8425346 0.0865118669 0.496757686 0.75767035 10 27504312 27504313 2 + 0.311 0.197 -0.871
ENSG00000099246 E009 1.2050307 0.0804706662 0.476547192 0.74302842 10 27504314 27504317 4 + 0.392 0.269 -0.771
ENSG00000099246 E010 1.8215170 0.0104988070 0.866114464 0.95386721 10 27504318 27504327 10 + 0.460 0.434 -0.134
ENSG00000099246 E011 3.9085702 0.0776481701 0.665082923 0.86071898 10 27504328 27504369 42 + 0.659 0.724 0.271
ENSG00000099246 E012 4.7593104 0.0440537612 0.641020996 0.84760172 10 27504370 27504376 7 + 0.732 0.789 0.229
ENSG00000099246 E013 4.8857524 0.0574351189 0.539008906 0.78755198 10 27504377 27504382 6 + 0.732 0.809 0.307
ENSG00000099246 E014 6.1993467 0.0243724550 0.929663352 0.97937143 10 27504383 27504412 30 + 0.862 0.846 -0.064
ENSG00000099246 E015 4.9540706 0.0727982038 0.449407963 0.72315600 10 27504413 27504437 25 + 0.823 0.699 -0.496
ENSG00000099246 E016 0.1170040 0.0117034648 0.736224579   10 27504438 27504448 11 + 0.083 0.000 -12.668
ENSG00000099246 E017 0.0000000       10 27504619 27504724 106 +      
ENSG00000099246 E018 0.0000000       10 27504979 27505075 97 +      
ENSG00000099246 E019 0.0000000       10 27505076 27505190 115 +      
ENSG00000099246 E020 0.0000000       10 27508902 27509033 132 +      
ENSG00000099246 E021 4.4626740 0.1211692653 0.432678683 0.71014552 10 27509875 27509888 14 + 0.794 0.647 -0.607
ENSG00000099246 E022 5.4413703 0.0905149666 0.363193771 0.65217940 10 27509889 27509930 42 + 0.862 0.724 -0.549
ENSG00000099246 E023 0.2356421 0.0156529775 0.369827594   10 27509931 27510490 560 + 0.152 0.000 -13.579
ENSG00000099246 E024 0.0000000       10 27512328 27512357 30 +      
ENSG00000099246 E025 0.1271363 0.0123603236 0.390270034   10 27513963 27513965 3 + 0.000 0.109 12.428
ENSG00000099246 E026 0.1271363 0.0123603236 0.390270034   10 27513966 27514054 89 + 0.000 0.109 12.428
ENSG00000099246 E027 0.0000000       10 27514055 27514119 65 +      
ENSG00000099246 E028 0.3543453 0.0157664222 0.179168813   10 27514120 27514420 301 + 0.212 0.000 -14.098
ENSG00000099246 E029 0.0000000       10 27526569 27526598 30 +      
ENSG00000099246 E030 9.9695474 0.0035102159 0.566019192 0.80455556 10 27526828 27526889 62 + 1.060 1.007 -0.193
ENSG00000099246 E031 1.6238837 0.4293763542 0.170142426 0.44226043 10 27526890 27528515 1626 + 0.212 0.587 2.186
ENSG00000099246 E032 4.3461123 0.0036929346 0.001822036 0.02374812 10 27528516 27531528 3013 + 0.519 0.896 1.576
ENSG00000099246 E033 0.0000000       10 27531529 27531615 87 +      
ENSG00000099246 E034 2.3692334 0.0823662709 0.021473148 0.13269848 10 27531616 27532382 767 + 0.311 0.700 1.937
ENSG00000099246 E035 0.1170040 0.0117034648 0.736224579   10 27532383 27532387 5 + 0.083 0.000 -12.668
ENSG00000099246 E036 0.0000000       10 27532388 27532487 100 +      
ENSG00000099246 E037 0.0000000       10 27532488 27532506 19 +      
ENSG00000099246 E038 9.3433945 0.0097436209 0.325325533 0.61782068 10 27532507 27532536 30 + 1.052 0.955 -0.357
ENSG00000099246 E039 11.1388436 0.0050199918 0.104762422 0.33838210 10 27532537 27532579 43 + 1.139 0.994 -0.526
ENSG00000099246 E040 0.3723461 0.1777210819 0.449392965   10 27532580 27533223 644 + 0.083 0.197 1.450
ENSG00000099246 E041 0.0000000       10 27533224 27533734 511 +      
ENSG00000099246 E042 20.4553603 0.0015876293 0.015265707 0.10640924 10 27533735 27533853 119 + 1.392 1.231 -0.562
ENSG00000099246 E043 0.7347164 0.0143527240 0.704086023 0.87968371 10 27533854 27533927 74 + 0.212 0.269 0.451
ENSG00000099246 E044 10.1059307 0.0034011557 0.822232106 0.93553577 10 27533928 27533940 13 + 1.052 1.031 -0.077
ENSG00000099246 E045 14.4921627 0.0029295666 0.966290163 0.99312496 10 27533941 27533994 54 + 1.189 1.185 -0.014
ENSG00000099246 E046 0.1265070 0.0123386117 0.390250757   10 27533995 27533998 4 + 0.000 0.109 12.428
ENSG00000099246 E047 6.6940973 0.0182264557 0.952272973 0.98810825 10 27537876 27537877 2 + 0.886 0.880 -0.026
ENSG00000099246 E048 26.8680560 0.0033106668 0.482117554 0.74704911 10 27537878 27538025 148 + 1.460 1.418 -0.145
ENSG00000099246 E049 11.5330868 0.0161086638 0.448326549 0.72237457 10 27538026 27538028 3 + 1.126 1.053 -0.262
ENSG00000099246 E050 40.8606351 0.0015761881 0.337330347 0.62909133 10 27538029 27538222 194 + 1.599 1.643 0.148
ENSG00000099246 E051 110.3782281 0.0001631455 0.085288713 0.30205672 10 27538223 27542001 3779 + 2.026 2.066 0.134
ENSG00000099246 E052 0.4801267 0.0153681642 0.492945713   10 27542002 27542205 204 + 0.212 0.109 -1.134
ENSG00000099246 E053 0.3709943 0.0166470959 0.406891248   10 27542206 27542752 547 + 0.083 0.197 1.451
ENSG00000099246 E054 0.2444846 0.0163702064 0.807450397   10 27542753 27543207 455 + 0.083 0.109 0.451

Help

Please Click HERE to learn more details about the results from DEXseq.