ENSG00000099290

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000282633 ENSG00000099290 No_inf pgKDN_inf WASHC2A protein_coding protein_coding 7.328361 9.331636 5.935529 0.7910997 0.1779761 -0.65187 2.8536347 1.4135847 4.3859432 0.8781354 0.7157558 1.62664439 0.42911667 0.151725 0.734325 0.582600 0.06730966 0.04299124 FALSE TRUE
ENST00000399339 ENSG00000099290 No_inf pgKDN_inf WASHC2A protein_coding protein_coding 7.328361 9.331636 5.935529 0.7910997 0.1779761 -0.65187 0.7673883 1.7035051 0.0000000 1.0232491 0.0000000 -7.42080670 0.09961667 0.179625 0.000000 -0.179625 0.59060442 0.04299124 FALSE TRUE
ENST00000454806 ENSG00000099290 No_inf pgKDN_inf WASHC2A protein_coding protein_coding 7.328361 9.331636 5.935529 0.7910997 0.1779761 -0.65187 0.3095218 0.6936516 0.1209481 0.4860012 0.1209481 -2.42586601 0.03978333 0.085950 0.019975 -0.065975 0.84772341 0.04299124 FALSE TRUE
ENST00000492914 ENSG00000099290 No_inf pgKDN_inf WASHC2A protein_coding protein_coding_CDS_not_defined 7.328361 9.331636 5.935529 0.7910997 0.1779761 -0.65187 0.6409221 0.8331628 0.8160505 0.4837023 0.4900875 -0.02958113 0.08818333 0.079125 0.144625 0.065500 0.94138093 0.04299124   TRUE
MSTRG.3404.10 ENSG00000099290 No_inf pgKDN_inf WASHC2A protein_coding   7.328361 9.331636 5.935529 0.7910997 0.1779761 -0.65187 2.3945050 4.3179266 0.4577306 0.5979000 0.4577306 -3.20992636 0.29266667 0.460800 0.076350 -0.384450 0.04299124 0.04299124 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099290 E001 0.0000000       10 50067888 50067906 19 +      
ENSG00000099290 E002 0.0000000       10 50067907 50067922 16 +      
ENSG00000099290 E003 0.0000000       10 50067923 50067923 1 +      
ENSG00000099290 E004 0.0000000       10 50067924 50067953 30 +      
ENSG00000099290 E005 0.3522653 0.026966013 0.055014304   10 50067954 50068008 55 + 0.271 0.000 -11.687
ENSG00000099290 E006 0.5879724 0.015400053 0.007599859 0.06671399 10 50068105 50068227 123 + 0.388 0.000 -14.796
ENSG00000099290 E007 0.0000000       10 50069510 50069546 37 +      
ENSG00000099290 E008 1.8160630 0.008017993 0.054139452 0.23159196 10 50069547 50069711 165 + 0.589 0.309 -1.474
ENSG00000099290 E009 0.0000000       10 50078126 50078152 27 +      
ENSG00000099290 E010 0.6181209 0.016094213 0.932275687 0.98028418 10 50078675 50078692 18 + 0.198 0.210 0.111
ENSG00000099290 E011 0.6181209 0.016094213 0.932275687 0.98028418 10 50078693 50078737 45 + 0.198 0.210 0.111
ENSG00000099290 E012 0.1186381 0.012015920 0.384700774   10 50080758 50080875 118 + 0.110 0.000 -13.006
ENSG00000099290 E013 0.0000000       10 50080876 50080931 56 +      
ENSG00000099290 E014 0.0000000       10 50084072 50084165 94 +      
ENSG00000099290 E015 1.5780924 0.008490882 0.156719132 0.42311106 10 50085497 50085558 62 + 0.519 0.309 -1.152
ENSG00000099290 E016 0.0000000       10 50085559 50085619 61 +      
ENSG00000099290 E017 2.5384073 0.005824165 0.022308743 0.13584733 10 50087275 50087322 48 + 0.702 0.390 -1.474
ENSG00000099290 E018 2.7846249 0.005440303 0.024286226 0.14285673 10 50090776 50090886 111 + 0.726 0.425 -1.381
ENSG00000099290 E019 1.1061838 0.033752304 0.883833477 0.96094644 10 50091431 50091449 19 + 0.333 0.309 -0.152
ENSG00000099290 E020 2.0842175 0.007134608 0.672860921 0.86447161 10 50091450 50091518 69 + 0.519 0.458 -0.304
ENSG00000099290 E021 1.1055170 0.011394453 0.880752456 0.95989862 10 50092162 50092233 72 + 0.333 0.309 -0.152
ENSG00000099290 E022 0.0000000       10 50093268 50093386 119 +      
ENSG00000099290 E023 0.2458395 0.016461940 0.799400270   10 50093860 50093917 58 + 0.110 0.082 -0.474
ENSG00000099290 E024 0.7423645 0.016610594 0.667464424 0.86152988 10 50095148 50095207 60 + 0.198 0.263 0.526
ENSG00000099290 E025 3.4704456 0.004173765 0.280962665 0.57421146 10 50095599 50095778 180 + 0.556 0.694 0.604
ENSG00000099290 E026 4.3092920 0.003734487 0.915166540 0.97340786 10 50097675 50097802 128 + 0.726 0.712 -0.059
ENSG00000099290 E027 3.6940377 0.018332531 0.882401671 0.96044820 10 50099978 50100064 87 + 0.677 0.656 -0.087
ENSG00000099290 E028 3.7911199 0.004600012 0.277924122 0.57121423 10 50104042 50104143 102 + 0.749 0.614 -0.567
ENSG00000099290 E029 2.1840099 0.011016017 0.108407478 0.34535630 10 50106334 50106364 31 + 0.620 0.390 -1.126
ENSG00000099290 E030 1.3419524 0.010106574 0.405772066 0.68844231 10 50106365 50106465 101 + 0.436 0.309 -0.737
ENSG00000099290 E031 1.2510354 0.010167450 0.142452787 0.40162303 10 50110101 50110270 170 + 0.198 0.425 1.526
ENSG00000099290 E032 0.7617499 0.013382500 0.025350447 0.14654352 10 50113895 50113997 103 + 0.000 0.351 13.411
ENSG00000099290 E033 0.0000000       10 50117906 50118058 153 +      
ENSG00000099290 E034 0.0000000       10 50119587 50119649 63 +      
ENSG00000099290 E035 3.0924962 0.007658767 0.542008700 0.78941150 10 50119650 50119769 120 + 0.556 0.636 0.356
ENSG00000099290 E036 3.0924962 0.007658767 0.542008700 0.78941150 10 50125113 50125241 129 + 0.556 0.636 0.356
ENSG00000099290 E037 0.3810317 0.050280140 0.187675389   10 50125369 50125449 81 + 0.000 0.210 12.593
ENSG00000099290 E038 1.2337596 0.107812642 0.907521593 0.97064680 10 50126057 50126179 123 + 0.333 0.351 0.112
ENSG00000099290 E039 0.6265540 0.252218244 0.406875426 0.68946900 10 50126180 50126508 329 + 0.110 0.263 1.527
ENSG00000099290 E040 0.3802764 0.020002392 0.183065573   10 50127160 50127222 63 + 0.000 0.210 12.615
ENSG00000099290 E041 0.0000000       10 50127583 50127795 213 +      
ENSG00000099290 E042 8.0094238 0.002258398 0.945134652 0.98496497 10 50129419 50129784 366 + 0.944 0.949 0.019
ENSG00000099290 E043 9.4028088 0.001619309 0.229725476 0.51828051 10 50129785 50130039 255 + 0.944 1.048 0.386
ENSG00000099290 E044 3.9604878 0.003763248 0.374373278 0.66203020 10 50130901 50131078 178 + 0.620 0.729 0.459
ENSG00000099290 E045 15.4795104 0.001107742 0.059210259 0.24424062 10 50132806 50133437 632 + 1.127 1.256 0.458
ENSG00000099290 E046 0.0000000       10 50133438 50133509 72 +      

Help

Please Click HERE to learn more details about the results from DEXseq.