ENSG00000099331

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000593533 ENSG00000099331 No_inf pgKDN_inf MYO9B protein_coding retained_intron 111.5474 120.5559 101.5933 24.59925 7.121177 -0.2468754 16.041810 14.667782 16.489540 2.299288 1.7882368 0.1687918 0.14816667 0.128900 0.163425 0.034525 8.069698e-01 5.847601e-11 FALSE  
ENST00000595641 ENSG00000099331 No_inf pgKDN_inf MYO9B protein_coding protein_coding 111.5474 120.5559 101.5933 24.59925 7.121177 -0.2468754 6.705595 9.315369 4.938677 3.309778 3.2767729 -0.9141179 0.06298333 0.078850 0.054500 -0.024350 8.345018e-01 5.847601e-11 FALSE  
ENST00000597073 ENSG00000099331 No_inf pgKDN_inf MYO9B protein_coding protein_coding 111.5474 120.5559 101.5933 24.59925 7.121177 -0.2468754 10.503659 9.484173 10.440364 1.881414 1.9652749 0.1384390 0.09865833 0.085450 0.106875 0.021425 8.583501e-01 5.847601e-11 FALSE  
ENST00000598464 ENSG00000099331 No_inf pgKDN_inf MYO9B protein_coding retained_intron 111.5474 120.5559 101.5933 24.59925 7.121177 -0.2468754 10.205914 22.183253 8.434491 22.183253 8.4344908 -1.3940388 0.06133333 0.114475 0.069525 -0.044950 1.000000e+00 5.847601e-11    
ENST00000599420 ENSG00000099331 No_inf pgKDN_inf MYO9B protein_coding retained_intron 111.5474 120.5559 101.5933 24.59925 7.121177 -0.2468754 10.089124 11.701643 5.620268 1.463054 0.9976222 -1.0566678 0.09323333 0.109575 0.054400 -0.055175 4.968523e-01 5.847601e-11 FALSE  
ENST00000682292 ENSG00000099331 No_inf pgKDN_inf MYO9B protein_coding protein_coding 111.5474 120.5559 101.5933 24.59925 7.121177 -0.2468754 10.621382 6.643670 13.368975 3.199542 4.7467293 1.0077454 0.10065833 0.068200 0.129675 0.061475 8.467079e-01 5.847601e-11 FALSE  
MSTRG.14732.1 ENSG00000099331 No_inf pgKDN_inf MYO9B protein_coding   111.5474 120.5559 101.5933 24.59925 7.121177 -0.2468754 6.307224 0.000000 9.054339 0.000000 1.7540231 9.8240581 0.06037500 0.000000 0.093275 0.093275 5.847601e-11 5.847601e-11 FALSE  
MSTRG.14732.30 ENSG00000099331 No_inf pgKDN_inf MYO9B protein_coding   111.5474 120.5559 101.5933 24.59925 7.121177 -0.2468754 11.621078 12.832514 9.919398 2.581502 0.7500309 -0.3711494 0.10901667 0.122025 0.097600 -0.024425 9.389397e-01 5.847601e-11 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099331 E001 0.0000000       19 17075750 17075758 9 +      
ENSG00000099331 E002 0.3809057 0.0158498658 1.136525e-01   19 17075759 17075766 8 + 0.000 0.235 10.455
ENSG00000099331 E003 0.7437465 0.0140171386 4.522154e-01 7.254275e-01 19 17075767 17075776 10 + 0.177 0.291 0.929
ENSG00000099331 E004 1.1065249 0.0109052798 8.020585e-01 9.261434e-01 19 17075777 17075780 4 + 0.302 0.341 0.251
ENSG00000099331 E005 1.2251630 0.0103189457 9.335429e-01 9.808411e-01 19 17075781 17075785 5 + 0.353 0.341 -0.071
ENSG00000099331 E006 3.6370325 0.0111973953 1.201620e-01 3.664791e-01 19 17075786 17075826 41 + 0.761 0.560 -0.859
ENSG00000099331 E007 5.7013601 0.0026746586 3.927111e-02 1.919554e-01 19 17075827 17075874 48 + 0.931 0.704 -0.890
ENSG00000099331 E008 0.3807797 0.0317545522 1.160554e-01   19 17101656 17101659 4 + 0.000 0.235 12.836
ENSG00000099331 E009 7.1534107 0.0228768080 3.494466e-02 1.787976e-01 19 17101660 17101717 58 + 1.023 0.779 -0.927
ENSG00000099331 E010 47.7353855 0.0006751843 1.001198e-03 1.502466e-02 19 17101718 17102181 464 + 1.757 1.614 -0.486
ENSG00000099331 E011 46.2578358 0.0004392539 4.739754e-01 7.407961e-01 19 17102182 17102557 376 + 1.689 1.660 -0.102
ENSG00000099331 E012 5.5038884 0.0034470958 7.477909e-01 9.005148e-01 19 17103257 17103789 533 + 0.831 0.796 -0.135
ENSG00000099331 E013 7.4644309 0.0018403826 7.401413e-01 8.968699e-01 19 17145397 17145491 95 + 0.943 0.912 -0.118
ENSG00000099331 E014 0.0000000       19 17152644 17152706 63 +      
ENSG00000099331 E015 15.5075848 0.0269700067 3.265597e-01 6.189440e-01 19 17153967 17154066 100 + 1.263 1.172 -0.321
ENSG00000099331 E016 28.3749909 0.0006049646 3.571564e-01 6.468311e-01 19 17154315 17154415 101 + 1.493 1.443 -0.171
ENSG00000099331 E017 30.4425835 0.0005019960 2.677379e-01 5.611977e-01 19 17156909 17157038 130 + 1.526 1.469 -0.199
ENSG00000099331 E018 22.2044933 0.0021085845 1.031957e-01 3.357767e-01 19 17159395 17159484 90 + 1.416 1.314 -0.357
ENSG00000099331 E019 24.9441358 0.0006828606 4.293218e-01 7.075845e-01 19 17162350 17162466 117 + 1.437 1.392 -0.156
ENSG00000099331 E020 18.6135214 0.0022354522 7.008090e-02 2.678959e-01 19 17162988 17163122 135 + 1.219 1.347 0.451
ENSG00000099331 E021 1.2336930 0.1013444949 6.465237e-01 8.503871e-01 19 17167943 17168064 122 + 0.302 0.386 0.513
ENSG00000099331 E022 6.7636373 0.0330883703 5.344951e-01 7.845060e-01 19 17172336 17172374 39 + 0.846 0.924 0.298
ENSG00000099331 E023 19.9752525 0.0006974616 2.802864e-02 1.564255e-01 19 17172375 17172477 103 + 1.391 1.248 -0.496
ENSG00000099331 E024 14.9147728 0.0009126040 1.140519e-03 1.658026e-02 19 17172759 17172812 54 + 1.313 1.070 -0.865
ENSG00000099331 E025 20.1836611 0.0006555291 4.974161e-03 4.942454e-02 19 17172813 17172923 111 + 1.412 1.230 -0.634
ENSG00000099331 E026 13.3900916 0.0010183815 5.627571e-01 8.024492e-01 19 17172924 17172963 40 + 1.132 1.179 0.168
ENSG00000099331 E027 23.4007938 0.0006264474 7.697949e-01 9.111202e-01 19 17175663 17175741 79 + 1.395 1.379 -0.056
ENSG00000099331 E028 0.8696915 0.0130339293 2.839351e-01 5.776815e-01 19 17177797 17177886 90 + 0.177 0.341 1.251
ENSG00000099331 E029 0.9879139 0.0965471586 5.410346e-01 7.887541e-01 19 17180645 17180926 282 + 0.244 0.341 0.666
ENSG00000099331 E030 29.2446872 0.0004736121 4.658272e-01 7.347466e-01 19 17180927 17181040 114 + 1.500 1.462 -0.131
ENSG00000099331 E031 0.3549069 0.0296091088 9.504285e-02   19 17183737 17183828 92 + 0.244 0.000 -13.643
ENSG00000099331 E032 15.6861658 0.0008946524 9.578387e-01 9.899059e-01 19 17183829 17183868 40 + 1.219 1.224 0.019
ENSG00000099331 E033 2.8495487 0.0094710718 1.901601e-01 4.692317e-01 19 17183869 17184002 134 + 0.478 0.661 0.836
ENSG00000099331 E034 5.0994580 0.0088091956 1.524945e-02 1.063439e-01 19 17184511 17184864 354 + 0.603 0.899 1.202
ENSG00000099331 E035 38.4639650 0.0003636247 2.017132e-01 4.840898e-01 19 17184865 17184987 123 + 1.561 1.624 0.216
ENSG00000099331 E036 29.3996140 0.0004952299 7.782089e-01 9.148664e-01 19 17185921 17186001 81 + 1.489 1.476 -0.047
ENSG00000099331 E037 28.5561645 0.0042380041 1.227331e-01 3.707980e-01 19 17187935 17188045 111 + 1.517 1.424 -0.318
ENSG00000099331 E038 24.8756814 0.0081080750 8.984749e-01 9.666287e-01 19 17191097 17191219 123 + 1.416 1.408 -0.028
ENSG00000099331 E039 48.9322954 0.0009746584 2.746789e-01 5.681520e-01 19 17192746 17193062 317 + 1.722 1.675 -0.158
ENSG00000099331 E040 172.7360282 0.0004681949 1.747021e-01 4.485141e-01 19 17194556 17195473 918 + 2.255 2.225 -0.102
ENSG00000099331 E041 25.9049960 0.0005082973 2.290019e-01 5.177075e-01 19 17197792 17197858 67 + 1.464 1.396 -0.234
ENSG00000099331 E042 0.3706473 0.0165986985 6.170025e-01   19 17198118 17198183 66 + 0.097 0.170 0.929
ENSG00000099331 E043 43.5114008 0.0003261067 9.344280e-01 9.810672e-01 19 17198184 17198308 125 + 1.645 1.650 0.018
ENSG00000099331 E044 50.1345472 0.0002892579 9.166485e-01 9.737743e-01 19 17200293 17200426 134 + 1.705 1.711 0.021
ENSG00000099331 E045 73.1022557 0.0002134327 6.000927e-02 2.458137e-01 19 17200639 17200829 191 + 1.902 1.838 -0.216
ENSG00000099331 E046 49.6873616 0.0057058233 8.037456e-01 9.270952e-01 19 17201926 17202024 99 + 1.696 1.711 0.050
ENSG00000099331 E047 0.0000000       19 17202129 17202129 1 +      
ENSG00000099331 E048 70.3855659 0.0002264647 7.781689e-01 9.148664e-01 19 17202130 17202303 174 + 1.847 1.858 0.040
ENSG00000099331 E049 11.4473845 0.0015874831 2.816182e-01 5.749939e-01 19 17202842 17202844 3 + 1.043 1.135 0.335
ENSG00000099331 E050 25.8158229 0.0005425169 3.885842e-01 6.743645e-01 19 17202845 17202869 25 + 1.452 1.404 -0.167
ENSG00000099331 E051 24.9534096 0.0008978771 3.546076e-01 6.443389e-01 19 17202870 17202883 14 + 1.441 1.387 -0.184
ENSG00000099331 E052 9.3464698 0.0152483128 5.503416e-04 9.404982e-03 19 17202884 17203004 121 + 0.779 1.150 1.388
ENSG00000099331 E053 10.0673459 0.0252237369 7.821378e-03 6.807313e-02 19 17203005 17203146 142 + 0.862 1.158 1.092
ENSG00000099331 E054 50.6137497 0.0002788768 9.220825e-01 9.758113e-01 19 17203147 17203258 112 + 1.713 1.711 -0.008
ENSG00000099331 E055 36.2546472 0.0012056959 2.333975e-01 5.222829e-01 19 17205263 17205336 74 + 1.536 1.599 0.214
ENSG00000099331 E056 62.0708322 0.0021464013 7.375359e-01 8.958820e-01 19 17205960 17206152 193 + 1.790 1.807 0.054
ENSG00000099331 E057 47.1133565 0.0003444170 4.395477e-01 7.155186e-01 19 17206248 17206376 129 + 1.698 1.666 -0.108
ENSG00000099331 E058 19.4078601 0.0007109137 1.756700e-01 4.498214e-01 19 17206679 17206688 10 + 1.354 1.266 -0.307
ENSG00000099331 E059 28.5774696 0.0005116721 1.494767e-01 4.117907e-01 19 17206689 17206773 85 + 1.510 1.432 -0.269
ENSG00000099331 E060 8.7758608 0.0130118310 2.933740e-01 5.869656e-01 19 17206774 17206784 11 + 1.043 0.937 -0.393
ENSG00000099331 E061 1.3581555 0.0118473382 4.172589e-01 6.970318e-01 19 17206785 17206828 44 + 0.302 0.427 0.736
ENSG00000099331 E062 6.3334274 0.0022863705 1.982992e-01 4.797286e-01 19 17207113 17207212 100 + 0.931 0.796 -0.518
ENSG00000099331 E063 0.0000000       19 17207213 17207244 32 +      
ENSG00000099331 E064 0.2455571 0.0161697630 9.669858e-01   19 17209566 17209585 20 + 0.097 0.093 -0.071
ENSG00000099331 E065 31.4258830 0.0099104976 4.935099e-01 7.553982e-01 19 17209586 17209709 124 + 1.533 1.489 -0.150
ENSG00000099331 E066 5.8811620 0.0759046113 5.024430e-03 4.980474e-02 19 17209710 17209840 131 + 0.545 0.993 1.816
ENSG00000099331 E067 7.2179238 0.0337356433 7.077185e-03 6.353211e-02 19 17209841 17209988 148 + 0.700 1.043 1.321
ENSG00000099331 E068 24.8482768 0.0005472447 1.691928e-13 2.433399e-11 19 17209989 17210332 344 + 1.098 1.574 1.663
ENSG00000099331 E069 25.4904584 0.0009114693 5.950706e-02 2.446631e-01 19 17210333 17210380 48 + 1.358 1.472 0.393
ENSG00000099331 E070 13.9700649 0.0054906478 5.598821e-07 2.757688e-05 19 17210381 17210442 62 + 0.891 1.328 1.583
ENSG00000099331 E071 21.2451169 0.0025730120 3.652454e-06 1.430584e-04 19 17210443 17210590 148 + 1.148 1.469 1.123
ENSG00000099331 E072 15.3181406 0.0017851758 1.297229e-06 5.835257e-05 19 17210591 17210714 124 + 0.967 1.352 1.376
ENSG00000099331 E073 66.8862847 0.0002126025 7.151255e-01 8.851918e-01 19 17210715 17210848 134 + 1.837 1.826 -0.039
ENSG00000099331 E074 0.3629695 0.0165658961 5.512855e-01   19 17210849 17210852 4 + 0.177 0.093 -1.071
ENSG00000099331 E075 33.2586178 0.0026494230 7.413527e-01 8.974304e-01 19 17211647 17211650 4 + 1.523 1.543 0.067
ENSG00000099331 E076 77.3516754 0.0012532393 9.485210e-01 9.866788e-01 19 17211651 17211774 124 + 1.894 1.893 -0.002
ENSG00000099331 E077 17.9034853 0.0020220866 8.648102e-01 9.532336e-01 19 17211775 17211786 12 + 1.269 1.282 0.048
ENSG00000099331 E078 19.7115957 0.0105349416 1.404856e-01 3.988495e-01 19 17211787 17211894 108 + 1.251 1.366 0.402
ENSG00000099331 E079 71.0320087 0.0002241990 7.783677e-02 2.854456e-01 19 17211895 17212059 165 + 1.888 1.827 -0.205
ENSG00000099331 E080 372.7108715 0.0002787982 1.901946e-01 4.692317e-01 19 17212060 17213357 1298 + 2.560 2.582 0.074
ENSG00000099331 E081 0.2459655 0.0163791690 9.669176e-01   19 17214460 17214537 78 + 0.097 0.093 -0.071

Help

Please Click HERE to learn more details about the results from DEXseq.