ENSG00000099622

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000320936 ENSG00000099622 No_inf pgKDN_inf CIRBP protein_coding protein_coding 127.1288 164.5519 101.0854 7.397059 1.967954 -0.702913 34.931056 36.808544 41.003141 4.606628 3.6042653 0.1556536 0.28773333 0.224700 0.404250 0.179550 0.01771183 0.01492513 FALSE TRUE
ENST00000413636 ENSG00000099622 No_inf pgKDN_inf CIRBP protein_coding protein_coding 127.1288 164.5519 101.0854 7.397059 1.967954 -0.702913 7.921273 14.830996 0.000000 9.764334 0.0000000 -10.5353722 0.05303333 0.084775 0.000000 -0.084775 0.81644909 0.01492513 FALSE TRUE
ENST00000585630 ENSG00000099622 No_inf pgKDN_inf CIRBP protein_coding protein_coding 127.1288 164.5519 101.0854 7.397059 1.967954 -0.702913 13.109904 7.689853 16.913151 4.470238 2.4485776 1.1360953 0.11281667 0.043950 0.168725 0.124775 0.25892737 0.01492513 FALSE TRUE
ENST00000621399 ENSG00000099622 No_inf pgKDN_inf CIRBP protein_coding retained_intron 127.1288 164.5519 101.0854 7.397059 1.967954 -0.702913 5.899038 14.461383 1.574598 5.221693 1.5745979 -3.1910142 0.03743333 0.083900 0.014750 -0.069150 0.40919197 0.01492513   FALSE
ENST00000628979 ENSG00000099622 No_inf pgKDN_inf CIRBP protein_coding protein_coding 127.1288 164.5519 101.0854 7.397059 1.967954 -0.702913 14.445909 18.523637 16.024803 6.488590 0.7662933 -0.2089394 0.11764167 0.115400 0.158700 0.043300 0.83122176 0.01492513 FALSE TRUE
MSTRG.14190.19 ENSG00000099622 No_inf pgKDN_inf CIRBP protein_coding   127.1288 164.5519 101.0854 7.397059 1.967954 -0.702913 20.143531 36.599597 8.927175 4.615461 3.0021963 -2.0343311 0.14774167 0.227425 0.088200 -0.139225 0.43704388 0.01492513 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099622 E001 0.2363338 1.565730e-02 8.162230e-02   19 1259384 1259638 255 + 0.228 0.000 -11.669
ENSG00000099622 E002 0.1186381 1.179161e-02 2.549102e-01   19 1261156 1261165 10 + 0.129 0.000 -13.031
ENSG00000099622 E003 0.2451451 1.629635e-02 5.894040e-01   19 1261166 1261341 176 + 0.129 0.069 -0.996
ENSG00000099622 E004 0.0000000       19 1261342 1261381 40 +      
ENSG00000099622 E005 0.0000000       19 1261382 1261453 72 +      
ENSG00000099622 E006 0.0000000       19 1261454 1261641 188 +      
ENSG00000099622 E007 0.6259894 1.486474e-02 5.317628e-01 7.823053e-01 19 1261821 1262143 323 + 0.129 0.229 1.004
ENSG00000099622 E008 0.3804973 1.584465e-02 3.230785e-01   19 1264253 1264324 72 + 0.000 0.182 12.467
ENSG00000099622 E009 0.3809057 1.585418e-02 3.229920e-01   19 1264325 1264463 139 + 0.000 0.182 12.467
ENSG00000099622 E010 0.3611417 1.673953e-02 2.441625e-01   19 1264464 1264698 235 + 0.228 0.069 -1.996
ENSG00000099622 E011 0.3707734 1.676961e-02 1.000000e+00   19 1266653 1266701 49 + 0.129 0.129 0.004
ENSG00000099622 E012 0.3526461 2.767741e-02 2.487054e-02   19 1266798 1267087 290 + 0.309 0.000 -14.396
ENSG00000099622 E013 0.2362687 1.564809e-02 8.167397e-02   19 1267088 1267153 66 + 0.228 0.000 -13.960
ENSG00000099622 E014 0.2362687 1.564809e-02 8.167397e-02   19 1267154 1267165 12 + 0.228 0.000 -13.960
ENSG00000099622 E015 0.3634051 1.657053e-02 2.441958e-01   19 1267166 1267228 63 + 0.228 0.069 -1.996
ENSG00000099622 E016 0.1271363 1.234404e-02 1.000000e+00   19 1267229 1267292 64 + 0.000 0.069 10.949
ENSG00000099622 E017 0.0000000       19 1267293 1267338 46 +      
ENSG00000099622 E018 0.0000000       19 1267339 1267366 28 +      
ENSG00000099622 E019 0.0000000       19 1267367 1267411 45 +      
ENSG00000099622 E020 0.0000000       19 1267412 1267443 32 +      
ENSG00000099622 E021 0.0000000       19 1269266 1269267 2 +      
ENSG00000099622 E022 0.0000000       19 1269268 1269304 37 +      
ENSG00000099622 E023 0.2356421 1.561712e-02 8.169319e-02   19 1269305 1269326 22 + 0.228 0.000 -13.960
ENSG00000099622 E024 0.2356421 1.561712e-02 8.169319e-02   19 1269327 1269329 3 + 0.228 0.000 -13.960
ENSG00000099622 E025 0.5982032 1.500493e-02 3.438390e-02 1.771214e-01 19 1269330 1269330 1 + 0.377 0.069 -2.996
ENSG00000099622 E026 0.7168413 1.416062e-02 1.260560e-02 9.333751e-02 19 1269331 1269331 1 + 0.436 0.069 -3.318
ENSG00000099622 E027 0.7168413 1.416062e-02 1.260560e-02 9.333751e-02 19 1269332 1269332 1 + 0.436 0.069 -3.318
ENSG00000099622 E028 0.8441037 1.297739e-02 4.188330e-02 1.991167e-01 19 1269333 1269334 2 + 0.436 0.129 -2.318
ENSG00000099622 E029 0.8441037 1.297739e-02 4.188330e-02 1.991167e-01 19 1269335 1269335 1 + 0.436 0.129 -2.318
ENSG00000099622 E030 0.8441037 1.297739e-02 4.188330e-02 1.991167e-01 19 1269336 1269336 1 + 0.436 0.129 -2.318
ENSG00000099622 E031 5.0603445 2.751403e-03 4.509478e-01 7.241534e-01 19 1269337 1269346 10 + 0.815 0.727 -0.352
ENSG00000099622 E032 7.8567431 1.891561e-03 2.700547e-02 1.527027e-01 19 1269347 1269347 1 + 1.056 0.838 -0.815
ENSG00000099622 E033 8.1110157 1.766679e-03 4.386105e-02 2.045661e-01 19 1269348 1269349 2 + 1.056 0.860 -0.733
ENSG00000099622 E034 10.0878557 1.384250e-03 4.936996e-02 2.191178e-01 19 1269350 1269350 1 + 1.129 0.953 -0.642
ENSG00000099622 E035 10.9571654 1.247853e-03 6.899984e-02 2.654188e-01 19 1269351 1269351 1 + 1.150 0.993 -0.571
ENSG00000099622 E036 18.3422669 7.835611e-04 1.554605e-02 1.077574e-01 19 1269352 1269355 4 + 1.364 1.197 -0.586
ENSG00000099622 E037 47.4620495 3.420712e-04 1.664796e-03 2.214828e-02 19 1269356 1269407 52 + 1.745 1.606 -0.473
ENSG00000099622 E038 42.8183365 3.300165e-04 1.239452e-02 9.226739e-02 19 1269408 1269410 3 + 1.688 1.571 -0.397
ENSG00000099622 E039 0.0000000       19 1269912 1269915 4 +      
ENSG00000099622 E040 5.2841101 1.542872e-02 1.674795e-01 4.380833e-01 19 1270867 1270879 13 + 0.879 0.713 -0.659
ENSG00000099622 E041 7.9984666 2.016953e-03 1.071324e-01 3.430060e-01 19 1270880 1270882 3 + 1.028 0.870 -0.594
ENSG00000099622 E042 7.1338551 5.789112e-03 1.353496e-01 3.910129e-01 19 1270883 1270927 45 + 0.984 0.827 -0.595
ENSG00000099622 E043 52.9437101 2.743866e-04 6.415700e-03 5.928120e-02 19 1270928 1270942 15 + 1.776 1.662 -0.388
ENSG00000099622 E044 88.7067408 1.853369e-04 1.242679e-02 9.243230e-02 19 1270943 1271029 87 + 1.976 1.895 -0.274
ENSG00000099622 E045 54.3718062 1.081010e-03 7.656104e-02 2.829218e-01 19 1271030 1271036 7 + 1.764 1.687 -0.259
ENSG00000099622 E046 2.8572332 7.771207e-03 7.708508e-01 9.116340e-01 19 1271037 1271120 84 + 0.534 0.577 0.197
ENSG00000099622 E047 1.0974011 1.137707e-02 1.771085e-01 4.515326e-01 19 1271121 1271139 19 + 0.436 0.229 -1.318
ENSG00000099622 E048 102.6993163 2.546737e-04 1.050145e-02 8.292611e-02 19 1271140 1271246 107 + 2.037 1.959 -0.262
ENSG00000099622 E049 5.1127096 2.687371e-03 2.165318e-01 5.026556e-01 19 1271247 1271328 82 + 0.649 0.804 0.637
ENSG00000099622 E050 48.6757053 7.996653e-03 8.007533e-02 2.904763e-01 19 1271329 1271361 33 + 1.732 1.631 -0.341
ENSG00000099622 E051 31.3651630 1.026289e-02 1.102075e-01 3.483928e-01 19 1271362 1271365 4 + 1.551 1.442 -0.373
ENSG00000099622 E052 40.6967007 1.026190e-02 3.166919e-02 1.681279e-01 19 1271366 1271467 102 + 1.678 1.542 -0.466
ENSG00000099622 E053 3.4747821 5.682477e-02 9.170573e-01 9.739400e-01 19 1271468 1271550 83 + 0.614 0.633 0.083
ENSG00000099622 E054 54.3034796 2.582451e-04 7.259425e-05 1.810961e-03 19 1271551 1271632 82 + 1.817 1.653 -0.554
ENSG00000099622 E055 3.7021812 3.844587e-03 4.511567e-01 7.242931e-01 19 1271633 1271980 348 + 0.712 0.615 -0.411
ENSG00000099622 E056 43.2568322 3.255685e-04 1.874120e-03 2.433195e-02 19 1271981 1271981 1 + 1.709 1.565 -0.489
ENSG00000099622 E057 97.0714540 9.717860e-04 1.518167e-04 3.335268e-03 19 1271982 1272051 70 + 2.042 1.917 -0.420
ENSG00000099622 E058 97.6998383 6.453871e-03 3.519103e-05 9.895689e-04 19 1272052 1272426 375 + 1.819 2.018 0.667
ENSG00000099622 E059 403.3458945 7.067335e-05 9.120831e-04 1.398700e-02 19 1272427 1272916 490 + 2.608 2.560 -0.157
ENSG00000099622 E060 57.8218794 2.573063e-04 4.156021e-01 6.957317e-01 19 1272917 1272924 8 + 1.761 1.729 -0.110
ENSG00000099622 E061 83.6872888 2.460814e-04 3.028022e-01 5.959462e-01 19 1272925 1272968 44 + 1.920 1.886 -0.116
ENSG00000099622 E062 79.2614040 1.997825e-04 6.710525e-01 8.634542e-01 19 1272969 1273025 57 + 1.863 1.879 0.055
ENSG00000099622 E063 136.0744553 1.305397e-04 1.395009e-05 4.557141e-04 19 1273026 1273493 468 + 2.018 2.142 0.413
ENSG00000099622 E064 15.4652401 1.728789e-03 3.469938e-07 1.794131e-05 19 1273494 1273503 10 + 0.815 1.291 1.746
ENSG00000099622 E065 24.9396040 6.226623e-04 1.779504e-06 7.684207e-05 19 1273504 1273553 50 + 1.128 1.466 1.183
ENSG00000099622 E066 24.5126824 5.581486e-04 1.342648e-04 3.023566e-03 19 1273554 1273600 47 + 1.181 1.445 0.923
ENSG00000099622 E067 44.6410185 4.674752e-03 6.422687e-06 2.324840e-04 19 1273601 1273715 115 + 1.430 1.698 0.915
ENSG00000099622 E068 164.9146070 1.087133e-04 2.321276e-27 1.117819e-24 19 1273716 1274306 591 + 1.968 2.263 0.988
ENSG00000099622 E069 32.8987149 4.550555e-04 1.166451e-02 8.891651e-02 19 1274307 1274350 44 + 1.395 1.542 0.503
ENSG00000099622 E070 36.5619211 3.673406e-04 7.014370e-04 1.137784e-02 19 1274351 1274440 90 + 1.407 1.596 0.649
ENSG00000099622 E071 6.4857520 2.173248e-03 1.956811e-01 4.760212e-01 19 1274441 1274444 4 + 0.740 0.890 0.589
ENSG00000099622 E072 20.1109591 7.181299e-03 6.587877e-01 8.574650e-01 19 1274445 1274648 204 + 1.270 1.306 0.126
ENSG00000099622 E073 15.5324828 2.016515e-03 7.030225e-04 1.139173e-02 19 1274649 1274651 3 + 0.968 1.263 1.063
ENSG00000099622 E074 34.1289181 5.768939e-03 2.989209e-04 5.786791e-03 19 1274652 1274880 229 + 1.337 1.579 0.832

Help

Please Click HERE to learn more details about the results from DEXseq.