ENSG00000099804

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000215574 ENSG00000099804 No_inf pgKDN_inf CDC34 protein_coding protein_coding 43.44454 44.47105 41.94988 1.478581 2.786719 -0.0841801 22.240705 18.9880390 23.237049 3.3423385 1.463761 0.2911971 0.52836667 0.432950 0.566400 0.133450 0.67996144 0.02346964 FALSE TRUE
ENST00000586283 ENSG00000099804 No_inf pgKDN_inf CDC34 protein_coding protein_coding 43.44454 44.47105 41.94988 1.478581 2.786719 -0.0841801 1.869077 0.3658929 3.906188 0.3658929 2.198560 3.3810566 0.04524167 0.007525 0.096275 0.088750 0.38273323 0.02346964 FALSE FALSE
ENST00000593036 ENSG00000099804 No_inf pgKDN_inf CDC34 protein_coding protein_coding_CDS_not_defined 43.44454 44.47105 41.94988 1.478581 2.786719 -0.0841801 2.113967 6.3419005 0.000000 3.1941378 0.000000 -9.3110445 0.04717500 0.141525 0.000000 -0.141525 0.02346964 0.02346964   FALSE
ENST00000606400 ENSG00000099804 No_inf pgKDN_inf CDC34 protein_coding retained_intron 43.44454 44.47105 41.94988 1.478581 2.786719 -0.0841801 6.279056 7.0084586 3.635698 2.7502061 2.103212 -0.9449591 0.13450000 0.153600 0.080825 -0.072775 0.80329529 0.02346964 FALSE TRUE
MSTRG.14131.1 ENSG00000099804 No_inf pgKDN_inf CDC34 protein_coding   43.44454 44.47105 41.94988 1.478581 2.786719 -0.0841801 9.838947 9.5111785 11.170949 1.4000596 2.928505 0.2318306 0.21834167 0.211850 0.256500 0.044650 0.86901130 0.02346964 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000099804 E001 2.6823525 0.0096675013 0.5643957885 0.80358241 19 531719 531759 41 + 0.603 0.530 -0.333
ENSG00000099804 E002 2.6823525 0.0096675013 0.5643957885 0.80358241 19 531760 531768 9 + 0.603 0.530 -0.333
ENSG00000099804 E003 28.4451747 0.0060704547 0.1412721484 0.39981234 19 531769 532031 263 + 1.510 1.428 -0.280
ENSG00000099804 E004 25.7216037 0.0005891512 0.6928900097 0.87442567 19 532032 532099 68 + 1.433 1.420 -0.042
ENSG00000099804 E005 16.1915172 0.0009948972 0.0240144118 0.14189832 19 532100 532108 9 + 1.308 1.158 -0.529
ENSG00000099804 E006 28.4559754 0.0006345901 0.0872505061 0.30614591 19 535837 535923 87 + 1.510 1.428 -0.281
ENSG00000099804 E007 16.6045660 0.0120966105 0.4876125270 0.75098929 19 536243 536278 36 + 1.205 1.277 0.252
ENSG00000099804 E008 21.5404684 0.0007170064 0.2605037462 0.55307465 19 536279 536340 62 + 1.308 1.388 0.278
ENSG00000099804 E009 0.8875663 0.1049169667 0.0101441211 0.08101777 19 536341 536715 375 + 0.000 0.427 11.526
ENSG00000099804 E010 0.9903107 0.0530483197 0.5614671705 0.80184318 19 536953 537012 60 + 0.244 0.341 0.667
ENSG00000099804 E011 40.2870788 0.0003933455 0.3282789284 0.62077106 19 537013 537147 135 + 1.632 1.599 -0.114
ENSG00000099804 E012 6.7927284 0.0074173157 0.1527823221 0.41697118 19 538678 538878 201 + 0.797 0.960 0.626
ENSG00000099804 E013 1.8955608 0.0265904354 0.0006569983 0.01079006 19 541217 541252 36 + 0.097 0.638 3.738
ENSG00000099804 E014 17.3779179 0.0008328719 0.4361338787 0.71255728 19 541339 541342 4 + 1.286 1.243 -0.151
ENSG00000099804 E015 17.7504179 0.0008166467 0.4863629793 0.75004761 19 541343 541345 3 + 1.291 1.254 -0.129
ENSG00000099804 E016 19.8839800 0.0007201993 0.8679662855 0.95472980 19 541346 541360 15 + 1.308 1.329 0.073
ENSG00000099804 E017 117.0354633 0.0054284963 0.0606210514 0.24720519 19 541361 542092 732 + 2.034 2.102 0.228

Help

Please Click HERE to learn more details about the results from DEXseq.